W.K. Seow

ORCID: 0000-0002-7876-4524
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About
Contact & Profiles
Research Areas
  • Dental Health and Care Utilization
  • Oral microbiology and periodontitis research
  • dental development and anomalies
  • Bone and Dental Protein Studies
  • Berberine and alkaloids research
  • Dental Erosion and Treatment
  • Cleft Lip and Palate Research
  • Urological Disorders and Treatments
  • Dental Trauma and Treatments
  • Oral and Maxillofacial Pathology
  • Dental Radiography and Imaging
  • Endodontics and Root Canal Treatments
  • Oral and Craniofacial Lesions
  • Forensic Anthropology and Bioarchaeology Studies
  • Streptococcal Infections and Treatments
  • Fluoride Effects and Removal
  • Infant Nutrition and Health
  • Antifungal resistance and susceptibility
  • Periodontal Regeneration and Treatments
  • Pediatric health and respiratory diseases
  • Dental Anxiety and Anesthesia Techniques
  • Dental Research and COVID-19
  • Infective Endocarditis Diagnosis and Management
  • Dental materials and restorations
  • Immune Response and Inflammation

The University of Queensland
2011-2020

In-Q-Tel
2015

The University of Adelaide
2007

The University of Notre Dame Australia
2007

Mater Misericordiae Hospital
2003

QIMR Berghofer Medical Research Institute
2003

Boston Children's Hospital
1988-2001

Mater Children's Hospital
1985-1994

Chinese Academy of Medical Sciences & Peking Union Medical College
1994

University of Pittsburgh
1992

We hypothesize that S. mutans colonization occurs more frequently in pre-term children due to their relative immaturity. In this study of 172 predentate, six-month-old infants, we found 50% and 60% full-term harbored mutans. The was confirmed by repeat sampling. Although there were minor differences, factors associated with infection infants generally similar. both groups, increased frequency sugar ranked the most important factor (p < 0.001), followed breast-feeding habits which allowed...

10.1177/00220345010800120701 article EN Journal of Dental Research 2001-12-01

Abstract This paper aims to critically review current knowledge about the key factors involved in oral colonization of cariogenic group bacteria, mutans streptococci (MS) young children. MS, consisting mainly species Streptococcus and sobrinus , are commonly cultured from mouths infants, with prevalence infection ranging around 30 per cent 3 month old predentate children over 80 24 primary teeth. MS is usually transmitted through their mothers, risk transmission increases high maternal...

10.1111/j.1834-7819.2007.tb00471.x article EN Australian Dental Journal 2007-06-01

The aim of this case-control study 617 children was to investigate early childhood caries (ECC) risk indicators in a non-fluoridated region Australia. ECC cases were recruited from childcare facilities, public hospitals and private specialist clinics source different socioeconomic backgrounds. Non-ECC controls the same facilities. A multinomial logistic modelling approach used for statistical analysis. results showed that large percentage tested positive Streptococcus mutans if their mothers...

10.1159/000189704 article EN Caries Research 2009-01-01

Amelogenesis imperfecta (AI) represents hereditary conditions affecting the quality and quantity of enamel. Six genes are known to cause AI (AMELX, ENAM, MMP20, KLK4, FAM83H, WDR72). Our aim was determine distribution different gene mutations in a large population evaluate phenotype-genotype relationships. Affected unaffected family members were evaluated clinically radiographically by one examiner. Genotyping completed using genomic DNA obtained from blood or saliva. A total 494 individuals...

10.1159/000324339 article EN Cells Tissues Organs 2011-01-01

We previously reported that, before tooth eruption, over one-half of infants aged 6 mos were already infected with Streptococcus mutans. The aim this investigation was to determine the colonization S. mutans after eruption in same cohort 111 (35 pre-term, 76 full-term). Our results showed that increased increasing age, so by 24 84% harbored bacteria (p < 0.01). mean and median ages dentate 15.7 16.0 mos, respectively. Factors associated sweetened fluids taken bed 0.01), frequent sugar...

10.1177/154405910308200703 article EN Journal of Dental Research 2003-07-01

X-linked amelogenesis imperfectas (AI) resulting from mutations in the amelogenin gene (AMELX) are phenotypically and genetically diverse. Amelogenin is predominant matrix protein developing enamel essential for normal formation. To date, 12 allelic AMELX have been described that purportedly result markedly different expressed products. We hypothesize these unique functionally altered proteins associated with distinct imperfecta phenotypes. The phenotypes fall generally into three...

10.1080/03008200390152124 article EN Connective Tissue Research 2003-01-01

Abstract Background: Although a few growth media are available for selective isolation of the cariogenic bacteria, Streptococcus mutans (S. mutans), it is still unclear as to which most efficacious. This study compared selectivity and sensitivity five different growing laboratory strain S. (NCTC 10449), enumerating from teeth group young children, aged 2–10 years. Methods: The tested in this were mitis salivarius with bacitracin (MSB), salivariuskanamycin‐bacitracin (MSKB),...

10.1111/j.1834-7819.2002.tb00298.x article EN Australian Dental Journal 2002-03-01
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