We aimed to assess the efficacy of greater occipital nerve (GON) blockade at chronic migraine (CM) treatment.Patients with CM were randomly divided into two groups 42. GON was administered four times (once per week) saline in group A or bupivacaine B. After 4 weeks treatment, blinding removed; A, achieved using bupivacaine, while B continued receive and once month, then followed for 2 months. Primary endpoint difference number headache days, duration headache, pain scores.Seventy-two 84...

Paracetamol, a centrally acting inhibitor of cyclooxygenase, has less gastrointestinal and platelet-inhibiting side effects is clinically better tolerated than nonsteroidal anti-inflammatory drugs. Therefore, it will be ideally suited for postoperative pain relief. In this prospective, double-blind, randomized, placebo-controlled study, we evaluated the analgesic efficacy, opioid-sparing effect on opioid-related adverse intravenous (IV) paracetamol in combination with IV morphine after...

Splanchnic nerve blockade is employed in the treatment of abdominal pain, resistant to medical management due various etiologies, particularly cases involving pancreatic cancer and pancreatitis. Different techniques are utilized during procedure, with radiofrequency ablation (RFA) neurolysis using neurolytic agents being two most frequently used methods. We retrospectively examined effects RFA combination a agent on pain scores. A total 15 patients (10 males, 5 females) diagnosed (11 cases),...

Peripheral nerve blocks have been used in primary headache treatment since a long time. In this study, we aimed to examine the efficiency of greater occipital (GON) block migraine prophylaxis.Data from without aura patients who had GON were collected and divided into two groups: Group PGON (n=25), which included under medical prophylaxis block, (n=53), only blocks. Migraine was diagnosed using International Headache Society (IHS) classification. Data 78 analyzed. attack frequency, duration,...

We investigated the postoperative analgesic efficacy and effect on total tramadol consumption of intravenous dexketoprofen trometamol, a new nonsteroidal anti-inflammatory drug, in patients that had undergone lumbar disc surgery.Sixty were included this placebo-controlled, randomized, double-blind study. General anesthesia was applied to both groups. Group D (n=30) received (50 mg) intravenously 30 minutes before end surgery at 12th hour, whereas group C 2 mL 0.9% NaCL same time points. All...

Background: A hypoperfusion–reperfusion human model is observed during and soon after laparoscopic surgery. The aim of the study was to research preventive effects etomidate, thiopental, propofol in induction on hypoperfusion– reperfusion phenomenon cholecystectomy. Methods: Thirty‐six consecutive ASA I–II patients were randomized into three groups 12 each. Anaesthesia induced with etomidate group 1, thiopental 2, 3. Venous blood samples obtained at different time points for measurement...

Tourniquet use is a common tool in surgical procedures of the limbs. Hydroxyethyl starch (HES) 130/0.4 not only has role replacement liquid deficits due to trauma, bleeding or shock, but it also effective enhancing tissue oxygen tension and regulation microcirculation. The aim this study was investigate how 6% HES affects ischaemia reperfusion skeletal muscle.An ischaemia/reperfusion model (3 2 h, respectively) applied 14 rabbits. Group S (n = 7) infused with 0.9% NaCl (0.2 ml kg(-1)...

To present a case of an epileptic seizure related to intravenous (IV) tramadol for pain control following total abdominal hysterectomy operation on patient with mental retardation and cerebellar ataxia.Tramadol is analgesic dual mechanism action has several side effects, one which seizure.A 42-year-old female ataxia presented after administration IV postoperative pain. Magnetic resonance imaging scans were normal, but laboratory tests showed hypocalcemia. Next, calcium replacement was...

We evaluated the characteristics of headache in migraine without aura and episodic tension-type diagnosed according to International Headache Society (IHS) Classification. Fifty 50 patients were selected prospectively. Fifty-eight percent migraineurs had pain a pulsating quality; 88% severe 74% unilateral pain; aggravation by routine physical activity was reported 96%. Episodic pressing quality 52%, moderate 40%, bilateral 82% aggravated 16%. Nausea and/or vomiting, photophobia phonophobia...

Paracetamol is one of the most widely used analgesics and antipyretics in world. It commonly analgesic antipyretic agent pregnancy. known to have toxic effects on liver, lung, kidney. In this study, we investigated long-term chronic paracetamol exposure kidney newborn rats at different trimesters

To examine the effects of right and left stellate ganglion block (SGB) on blood pressure RR, QT, QTc intervals in patients with primary Raynaud's phenomenon. Materials methods: Right SGBs were performed 8 mL 0.5% bupivacaine 10 There was an interval at least 1 week between blocks each patient. The RR QT measured before 5, 10, 15, 20, 30 min after block. calculated using Bazett's formula. Results: longer 20 SGB when compared preblock value (P = 0.037 for P 0.008 QT). shorter than values...