Estefanía Espín

ORCID: 0000-0002-7926-0010
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About
Contact & Profiles
Research Areas
  • Adrenal Hormones and Disorders
  • Sexual Differentiation and Disorders
  • Cytokine Signaling Pathways and Interactions
  • COVID-19 Clinical Research Studies
  • COVID-19 and Mental Health
  • Global Maternal and Child Health
  • Hormonal and reproductive studies
  • Long-Term Effects of COVID-19
  • Global Health Care Issues
  • Complementary and Alternative Medicine Studies
  • Cancer, Hypoxia, and Metabolism
  • Vaccine Coverage and Hesitancy
  • Rheumatoid Arthritis Research and Therapies
  • Breastfeeding Practices and Influences
  • SARS-CoV-2 and COVID-19 Research
  • MicroRNA in disease regulation
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Healthcare Systems and Reforms
  • Communication and COVID-19 Impact
  • Maternal and Neonatal Healthcare
  • Innovation and Socioeconomic Development
  • Infant Nutrition and Health
  • Neonatal Respiratory Health Research
  • Psychedelics and Drug Studies
  • Radiopharmaceutical Chemistry and Applications

St. Paul's Hospital
2023

Prevention of Organ Failure
2023

Universidad de Las Américas
2019-2021

Central University of Ecuador
2021

University of the Americas
2020

INCLIVA Health Research Institute
2015

OBJECTIVE: To determine whether there is a relationship between access to health systems and out-of-pocket spending with socio demographic characteristics in Ecuador.METHODS: Retrospective analysis of national level data on household medical expenditure from the National Survey Household Income Expenditure Urban Rural Houses conducted by Ecuadorian Institute Statistics Census Databases as well other scientific, institutional, technical-administrative datasets.RESULTS: Families lowest...

10.5539/gjhs.v9n1p201 article EN cc-by Global Journal of Health Science 2016-05-19

Congenital adrenal hyperplasia (CAH) is a group of rare orphan disorders caused by mutations in seven different enzymes that impair cortisol biosynthesis. The 17α-hydroxylase deficiency (17OHD) one the less common forms CAH, corresponding to approximately 1% cases, with an estimated annual incidence 1 50,000 newborns. Cases description - two phenotypically female Ecuadorian sisters, both primary amenorrhea, absence secondary sexual characteristics, and osteoporosis. High blood pressure was...

10.1080/09513590.2019.1650342 article EN cc-by-nc-nd Gynecological Endocrinology 2019-08-29

e11592 Background: Despite the therapeutic success of trastuzumab, only 30% tumors that overexpress HER2 respond. The PI3K/AKT pathway appears to be an important mechanism resistance. It is known receptor and PI3K pathways can modulated by different miRNAs. purpose this study was investigate mechanisms in resistance trastuzumab evaluation inhibitory drugs relevant microRNAs context de novo Methods: cell line HCC1954, with treated inhibitors BKM120 (PI3K), MK2206 (Akt1/2/3), everolimus (mTOR)...

10.1200/jco.2015.33.15_suppl.e11592 article EN Journal of Clinical Oncology 2015-05-20

<p><strong>OBJECTIVE:</strong> The aim of this study was to analyze trends in infant breastfeeding and artificial milk consumption Ecuador from 2007 2014.</p><p><strong>METHODS: </strong>This descriptive observational includes all the available data collected adapted National Health Nutrition Survey Ecuador, ENSANUT, Ecuadorian Institute Census Statistics, national report International Marketing Services Enfarma EP. Descriptive inferential statistics...

10.5539/gjhs.v8n11p184 article EN cc-by Global Journal of Health Science 2016-03-23

On March 11, 2020, the World Health Organization (WHO) recognized COVID-19, disease caused by SARS-CoV-2 virus, as a pandemic. 1 This pandemic has claimed 640,016 lives worldwide, officially reported to WHO. 2 In parallel, an epidemic equally dangerous for human health; "infodemic" spread. Infodemic is term coined define information excess, some accurate and not, during epidemic, which could damage public health. 3 spreads rapidly, influencing behavior of population, avoiding their adherence...

10.21931/rb/2020.05.03.2 article EN Bionatura 2020-08-13

Congenital adrenal hyperplasia (CAH) is a group of rare orphan disorders, caused by mutations in seven different enzymes that impair cortisol biosynthesis. The 17α-hydroxylase deficiency (17OHD) one the less common forms CAH, corresponding to approximately 1% cases, with an estimated annual incidence 1 50 000 newborns. Two phenotypically female Ecuadorian sisters, both primary amenorrhea, absence secondary sexual characteristics, and osteoporosis. High blood pressure was present older...

10.3390/mol2net-05-06245 article EN cc-by Proceedings of MOL2NET 2018, International Conference on Multidisciplinary Sciences, 4th edition 2019-08-01

We hypothesize that high altitudes could have an adverse effect on neonatal health outcomes, especially among at-risk neonates. The current study aims to assess the association between higher survival time

10.1371/journal.pone.0253413 article EN cc-by PLoS ONE 2021-07-14

La Artritis Reumatoide (AR) es una enfermedad inflamatoria sistémica que afecta del 0.5 hasta el 2 % de la población mundial. En Ecuador, prevalencia reportada 0.9 %. Recientemente se han estudiado los polimorfismos en varios genes con fin encontrar su relación enfermedad. Dos más estudiados son -308 y -238 gen TNF-α. Nosotros analizamos presencia estos cuarenta individuos previamente diagnosticados AR veinticinco sanos mediante RCP-TR (endpoint genotyping). Se empleó ELISA para medio...

10.26807/remcb.v34i1-2.244 article ES Revista Ecuatoriana de Medicina y Ciencias Biológicas 2017-08-14
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