A5012068864- Photodynamic Therapy Research Studies
- Nanoplatforms for cancer theranostics
- Porphyrin and Phthalocyanine Chemistry
- Retinal Diseases and Treatments
- Chemical Thermodynamics and Molecular Structure
- Refrigeration and Air Conditioning Technologies
- Legionella and Acanthamoeba research
- bioluminescence and chemiluminescence research
- Phase Equilibria and Thermodynamics
- Thermal properties of materials
- Heat Transfer and Boiling Studies
- Glycosylation and Glycoproteins Research
- Advanced Chemical Sensor Technologies
- Scientific Measurement and Uncertainty Evaluation
- Free Radicals and Antioxidants
- Galectins and Cancer Biology
University of Lisbon
2006-2024
University of Coimbra
2023-2024
University of Aveiro
2014
Abstract The efficiency of 5,10,15,20‐tetrakis(1‐methylpyridinium‐4‐yl)porphyrin tetra‐iodide (Tetra‐Py + ‐Me) in the photodynamic inactivation single‐species biofilms Staphylococcus aureus , Pseudomonas aeruginosa and Candida albicans mixed S. C. was evaluated. effect on extracellular matrix P. also assessed. Irradiation with white light up to an energy dose 64.8 J cm −2 presence 20 μ m Tetra‐Py ‐Me caused significant all (3–6 log reductions), although susceptibility attenuated relation...
PorGal 8 , a porphyrin conjugated with dendritic galactose units, binds to galectin-1 in bladder cancer cells and induces localized cell death after light activation. Although it has been previously shown that photodynamic treatment (PDT) affects the cytoskeleton of cells, is still unclear how this change contributes PDT-induced death. In work, association between changes cytoskeletal constituents triggered by PDT was investigated two lines derived from transitional carcinoma (UM-UC-3...
Photodynamic Therapy (PDT) has been successfully used to treat different tumour types since its approval. However, the search for more powerful and selective photosensitisers (PSs) is still a hot research area on porphyrin (Por), chlorin (Chl), phthalocyanine (Pc) dyes. In this study, three new PSs of these families compounds were synthesized characterized as thioglycerol derivatives (tetra-thioglycerolporphyrin 1, tetra-thioglycerol 2, octa-thioglycerolphthalocyaninatozinc(II) 3). Their...