A5103272552- Electrochemical sensors and biosensors
- Electrochemical Analysis and Applications
- Diamond and Carbon-based Materials Research
- Carbon Nanotubes in Composites
- Semiconductor materials and devices
- Neuroscience and Neural Engineering
- Conducting polymers and applications
- Analytical Chemistry and Sensors
- Graphene research and applications
- Advancements in Battery Materials
- Graphene and Nanomaterials Applications
- Medicinal Plants and Neuroprotection
- Force Microscopy Techniques and Applications
- Photoreceptor and optogenetics research
- Ion channel regulation and function
- Pain Mechanisms and Treatments
- Advanced biosensing and bioanalysis techniques
- X-ray Spectroscopy and Fluorescence Analysis
- Cholinesterase and Neurodegenerative Diseases
- Electrocatalysts for Energy Conversion
- Poisoning and overdose treatments
- Forensic Toxicology and Drug Analysis
- X-ray Diffraction in Crystallography
- Advanced Sensor and Energy Harvesting Materials
- Molecular Sensors and Ion Detection
Aalto University
2015-2024
Canatu (Finland)
2023
SLAC National Accelerator Laboratory
2022
Stanford Synchrotron Radiation Lightsource
2022
VTT Technical Research Centre of Finland
2022
Espoo Music Institute
2015-2020
Department of Chemistry and Material Sciences
2017
Detailed information about the physicochemical properties of a given surface is important in order to understand and predict performance materials electrochemical applications. Here we present detailed X-ray absorption spectroscopy study two different tetrahedral amorphous-carbon (ta-C) thin films their subsequent characterization. The results show marked differences ta-C bulk properties, namely amount functional groups sp3/sp2 ratios, respectively. In particular, variation oxygen content...
Successful deployment of carbon nanomaterials in many applications, such as sensing, energy storage, and catalysis, relies on the selection, synthesis, tailoring surface properties. Predictive analysis behavior is difficult without detailed knowledge differences between various their functionalization, thus leaving selection process to traditional trial-and-error work. The present characterization fills this gap for nanomaterial properties with respect chemical states functionalization. We...
In clinical settings, the dosing and differential diagnosis of poisoning morphine (MO) codeine (CO) is challenging due to interindividual variations in metabolism. However, direct electrochemical detection these analytes from biological matrices inherently interference large concentrations anions, such as ascorbic acid (AA) uric (UA), well fouling electrode by proteins. this work, a disposable Nafion-coated single-walled carbon nanotube network (SWCNT) was developed. We show facile electron...
We prepare disposable single-walled carbon nanotube network electrodes for the detection of potent opioid fentanyl, currently a leading cause overdose deaths in USA. show repeatable dry transfer (SWCNT) networks to produce robust electrodes. This process directly produces highly conductive SWCNT without need any further modifications required conventional The realized electrode showed low background currents combined with spontaneous enrichment resulting high signal-to-noise ratio. With this...
In the present study, we designed an ultrasensitive sensing platform for evaluation of physiologically relevant values basal dopamine (DA) in a culture medium as complex biological environment. The proposed was fabricated via integration molecular imprinting technology with carbon hybrid nanomaterials. Carbon nanofibers (CNFs) were grown by using plasma-enhanced chemical vapor deposition (PECVD) on tetrahedral amorphous (ta-C) thin films silicon wafers. prepared ta-C/CNFs platforms...
We introduce a composite membrane comprised of multiwalled carbon nanotubes (MWCNTs) dispersed in matrix sulfated nanofibrillar cellulose (SNFC) and Nafion. The high negative charge densities the SNFC Nafion ionomers enhance cationic selectivity composite. is characterized by scanning electron (SEM) transmission (TEM) microscopies as well Fourier transform infrared (FTIR) Raman spectroscopies. Tetrahedral amorphous (ta-C) electrodes modified with are investigated potential dopamine (DA)...
Oxycodone is a strong opioid frequently used as an analgesic. Although proven efficacious in the management of moderate to severe acute pain and cancer pain, use oxycodone imposes risk adverse effects such addiction, overdose, death. Fast accurate determination blood concentration would enable personalized dosing monitoring analgesic well quick diagnostics possible overdose emergency care. However, addition parent drug, several metabolites are always present after dose oxycodone, date, there...
A disposable electrochemical test strip for the quantitative point-of-care (POC) determination of acetaminophen (paracetamol) in plasma and finger-prick whole blood was fabricated. The industrially scalable dry transfer process single-walled carbon nanotubes (SWCNTs) screen printing silver were combined to produce integrated strips. Nafion coating stabilized potential Ag reference electrode enabled selective detection spiked as well samples. strips able detect small 40 μL samples with a...
Four different types of crystalline and fibrillar nanocellulosic materials with functional groups (sulfate, carboxylate, amino-silane) are produced used to disperse commercial multiwalled carbon nanotubes (MWCNT). Aqueous nanocellulose/MWCNT dispersions drop-cast on tetrahedral amorphous (ta-C) substrates obtain highly stable composite electrodes. Their electrochemical properties studied using cyclic voltammetry (CV) measurements Ru(NH3)62+/3+, IrCl62–/3– redox probes, in electrolytes ionic...
Disposable single-use electrochemical sensor strips were used for quantitative detection of small concentrations morphine in untreated capillary whole blood. Single-walled carbon nanotube (SWCNT) networks fabricated on a polymer substrate to produce flexible, reproducible with integrated reference and counter electrodes, compatible industrial-scale processes. A thin Nafion coating was top the sensors enable direct These shown detect clinically relevant both buffer blood samples. Small 38 μL...
In this study we present for the first time tetrahedral amorphous carbon (ta-C)—a partially reduced graphene oxide (PRGO) hybrid electrode nanomaterial platform electrochemical sensing of dopamine (DA). Graphene was synthesized with modified Hummer's method. Before modification ta-C by drop casting, partial reduction GO carried out to improve properties and adhesion thin film. A facile nitric acid treatment that slightly reoxidized surface chemistry subsequently performed further electrodes....
Linking structural and compositional features with the observed electrochemical performance is often ambiguous sensitive to known unknown impurities. Here an extensive experimental investigation augmented by computational analyses linked characterization of in situ nitrogen-doped tetrahedral amorphous carbon thin films (ta-C:N). Raman spectroscopy combined X-ray reflectivity shows nitrogen disrupting sp3 C–C structure reference ta-C, supported observations graphitic substitution absorption...
Abstract Nanocellulose has emerged as a promising green dispersant for carbon nanotubes (CNTs), and there is an increasing trend in developing nanocellulose/CNT hybrid materials electrochemical detection of various small molecules. However, have been very few comprehensive studies investigating the role nanocellulosic material properties upon electroanalytical performance resultant electrodes. In this work, we demonstrate influence both nanocellulose functionalization geometry, utilizing...
Hydrogen peroxide (H2O2) is an important molecule produced in various enzymatic reactions. It especially electrochemical, biosensors detecting electroinactive analytes, such as glucose, cholesterol, and glutamate. Thus, there a strong need for materials that have high affinity H2O2 oxidation or reduction well enable immobilization sustain enzyme activity without any additional polymer layers. Carbon nanofibers (CNFs) directly grown on tetrahedral amorphous carbon (ta-C) are feasible...
Abstract Age structure in most developed countries is changing fast as the average lifespan increasing significantly, calling for solutions to provide improved treatments age-related neurological diseases and disorders. In order address these problems, a reliable way of recording information about neurotransmitters from vitro vivo applications needed better understand disorders well currently used treatments. Likewise, recent developments medicine, especially with opioid crisis, are...
Protein fouling is a critical issue in the development of electrochemical sensors for medical applications, as it can significantly impact their sensitivity, stability, and reliability. Modifying planar electrodes with conductive nanomaterials that possess high surface area, such carbon nanotubes (CNTs), has been shown to improve resistance sensitivity. However, inherent hydrophobicity CNTs poor dispersibility solvents pose challenges optimizing electrode architectures maximum Fortunately,...
Complex experimental investigation of the physical properties prospective electrode material based on Ti/ta-C bilayers in relation to their electrochemical behaviour, supported by computational simulation.
Biofouling affects the redox kinetics of outer and inner sphere probes on carbon surfaces drastically differently.