A5021586937- Medical Imaging Techniques and Applications
- Drug-Induced Adverse Reactions
- Cell Adhesion Molecules Research
- Biochemical and Molecular Research
- CRISPR and Genetic Engineering
- Drug-Induced Hepatotoxicity and Protection
- Inflammatory mediators and NSAID effects
- T-cell and B-cell Immunology
- Advanced Radiotherapy Techniques
- RNA modifications and cancer
- Monoclonal and Polyclonal Antibodies Research
- Lung Cancer Diagnosis and Treatment
Dana-Farber Cancer Institute
2023-2024
University of Massachusetts Boston
2023
Brigham Young University
2018-2021
Abstract αβ T-cell receptors (TCRs) recognize aberrant peptides bound to major histocompatibility complex molecules (pMHCs) on unhealthy cells, amplifying specificity and sensitivity through physical load placed the TCR-pMHC bond during immunosurveillance. To understand this mechanobiology, TCRs stimulated by abundantly sparsely arrayed epitopes (NP 366-374 /D b PA 224-233 , respectively) following in vivo influenza A virus infection were studied with optical tweezers. While certain NP...