A5013699602- Mental Health Treatment and Access
- Suicide and Self-Harm Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Cardiac Health and Mental Health
- Workplace Health and Well-being
- Schizophrenia research and treatment
- Child and Adolescent Psychosocial and Emotional Development
- Health disparities and outcomes
- Psychosomatic Disorders and Their Treatments
- Migration, Health and Trauma
- Tryptophan and brain disorders
- Employment and Welfare Studies
- Health, psychology, and well-being
- Psychology, Coaching, and Therapy
- Psychiatric care and mental health services
- Stress Responses and Cortisol
- Posttraumatic Stress Disorder Research
- Chronic Disease Management Strategies
- Mental Health Research Topics
- Child Abuse and Trauma
- COVID-19 and Mental Health
- Health, Environment, Cognitive Aging
- Gun Ownership and Violence Research
- Maternal Mental Health During Pregnancy and Postpartum
- Digital Mental Health Interventions
Ludwig-Maximilians-Universität München
2017-2025
LMU Klinikum
2019-2025
German Center for Pediatric and Adolescent Rheumatology
2024-2025
Philipps University of Marburg
2016-2022
Helmholtz Zentrum München
2011-2019
Ruhr University Bochum
2019
Jena University Hospital
2019
Universität Hamburg
2019
University Medical Center Hamburg-Eppendorf
2019
Heidelberg University
2019
To investigate risk factors associated with low subjective well-being (SWB) in men and women (≥65 years) separately a special focus on emotional distress. A cross-sectional analysis was conducted among 3602 participants (50.6% women) aged 65-90 years (mean age 72.8 years, SD ± 5.8) from the population-based KORA-Age study 2008/2009. SWB assessed using WHO-5 index (score range: 0 to 100). dichotomized into "low" ≤ 50) "high" > SWB. The association between potential by logistic regressions...
Background A link between severe mental stress and shorter telomere length (TL) has been suggested. We analysed the impact of Posttraumatic Stress Disorder (PTSD) on TL in general population postulated a dose-dependent association subjects suffering from partial PTSD compared to full PTSD. Methods Data are derived population-based KORA F4 study (2006–2008), located southern Germany including 3,000 individuals (1,449 men 1,551 women) with valid complete data. Leukocyte was measured using...
Abstract Depression constitutes a leading cause of disability worldwide. Despite extensive research on its interaction with psychobiological factors, associated pathways are far from being elucidated. Metabolomics, assessing the final products complex biochemical reactions, has emerged as valuable tool for exploring molecular pathways. We conducted metabolome-wide association analysis to investigate link between serum metabolome and depressed mood (DM) in 1411 participants KORA (Cooperative...
Abstract Background Antidepressants are first-line medications for many psychiatric disorders. However, their widespread long-term use in some indications (e.g., mild depression and insomnia) is concerning. Particularly older adults with comorbidities polypharmacy, who more susceptible to adverse drug reactions, the risks benefits of treatment should be regularly reviewed. The aim this consensus process was identify explicit criteria potentially inappropriate antidepressant (indicators)...
Omega-3 polyunsaturated fatty acids (PUFA) may affect the risk of cognitive decline in older adults.Cross-sectional analysis was conducted among 720 (50.4% women) participants aged 68-92 years (mean age: 77.6, SD ±6.2) population-based KORA-Age study. Eicosapentaenoic acid and docosahexaenoic (omega-3 index) were measured erythrocytes as a percentage total acids. The categories low (<5.7), intermediate (5.7-6.8), high (>6.8) levels omega-3 index built using tertiles. association between...
Abstract Aims Several psychosocial factors have been shown to increase the risk of Type 2 diabetes mellitus. This study investigated association between structural social support and incidence mellitus in men women. Methods Data were derived from three population‐based MONICA / KORA surveys conducted 1984–1995 Augsburg region (southern Germany) followed up by 2009. The population comprised 8952 participants (4669 men/4283 women) aged 30–74 years without at baseline. Structural was assessed...
General practitioners play an important role in the first-line care of individuals with mental health conditions. However, factors such as time constraints, limited experience managing conditions and high rates comorbidity may hinder adequate treatment. To improve psychological care, adopting a transdiagnostic approach shows potential. Research on interventions delivered by general is scarce. Thus, intervention adapted from Unified Protocol for Transdiagnostic Treatment Emotional Disorders...
Importance Collaborative care is a multicomponent intervention for patients with chronic disease in primary care. Previous meta-analyses have proven the effectiveness of collaborative depression; however, individual participant data (IPD) are needed to identify which components principal drivers this effect. Objective To assess biggest its reducing symptoms depression Data Sources were obtained from MEDLINE, Embase, Cochrane Library, PubMed, and PsycInfo as well references relevant...
Abstract We present a cross-sectional analysis of 1391 outpatients and 280 inpatients participating in subprojects the Research Training Group POKAL, whom 1609 had PHQ-9 score ≥ 5 62 reported depression with antidepressant use. Antidepressant use was lower among than (28.5% vs. 82.5%), higher levels SSRI monotherapy (44.1% 25.5%). Of users, 80.1% potentially inadequate treatment response, 21.7% high-risk those severe symptoms, 42.1% were undertreated. Key risk factors anxiety (for response)...
Zusammenfassung Hintergrund Patienten mit Suizidabsicht suchen vor dem Suizid oft ihren Hausarzt auf. Hausärzte können Schwierigkeiten haben, Suizidalität anzusprechen und Warnsignale zu erkennen. Diese qualitative Studie untersucht die Erfahrungen von Hausärzten im Umgang suizidalen Patienten, um Herausforderungen erleichternde Faktoren identifizieren. Methodik Befragung 21 mittels semistrukturierten Interviews, transkribiert qualitativ nach Kuckartz analysiert wurden. Ergebnisse bemühen...
Objective Investigating the association between mental health, quality of life, and SARS-CoV-2 infection in individuals need care compared to independent living individuals. Individuals include both home residents those receiving either through an outpatient service or from family members. Methods This cross-sectional study assessed symptoms depression (PHQ-9 > 9) anxiety (GAD-7 9), life (EQ-5D-5L, EQ-VAS), dementia (SIS), socio-demographic variables total sample (N = 978, 64.4% female,...
Abstract Background Constant high-level numbers of railway suicides indicate that prevention strategies against are urgently needed. The main question the present study was whether pre-crash suicide behaviour can be identified, using German Federal Police officers experience with suicidal events in related environments. Methods To collect information on behaviour, a questionnaire used and made available intranet. A total 202 subjects (mean age: 41 years, sex: 84.9% male) were included...
Suicide prediction during psychiatric in-patient treatment remains an unresolved challenge.To identify determinants of railway suicides in individuals receiving treatment.The study population was drawn from patients admitted to six hospitals Germany a 10-year period (1997-2006). Data 101 suicide cases were compared with control group discharged matched for age, gender and diagnosis.Predictors change therapist (OR = 22.86, P 0.004), suicidal ideation 7.92, P<0.001), negative or unchanged...
We evaluated a team-based program of exercises for patients with panic disorder or without agoraphobia (PDA) in primary care.419 PDA (mean age 46.2 years, standard deviation 14.4 years; 74% female) were included this cluster-randomized, controlled intervention trial. The blinded respect to their group assignment at baseline. Patients the (36 primary-care practices, 230 patients) underwent 23-week exercise combined case management, while control (37 189 received care. Symptoms anxiety...
To assess suicide mortality in comparison to traffic accidents and homicide deaths Germany the year 2010 compare years of life lost (YLL) due these unnatural deaths.