Sebastian Fischer

ORCID: 0000-0002-9609-3197
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About
Contact & Profiles
Research Areas
  • Financial Markets and Investment Strategies
  • Effects of Vibration on Health
  • Genetic Associations and Epidemiology
  • Corporate Finance and Governance
  • Machine Learning and Data Classification
  • Ergonomics and Musculoskeletal Disorders
  • Semantic Web and Ontologies
  • Metabolism and Genetic Disorders
  • Machine Learning and Algorithms
  • Pharmaceutical Practices and Patient Outcomes
  • Data Mining Algorithms and Applications
  • Corporate Social Responsibility Reporting
  • Auditing, Earnings Management, Governance
  • Protein Tyrosine Phosphatases
  • Treatment of Major Depression
  • Genomics and Rare Diseases
  • Digital Imaging for Blood Diseases
  • Metabolomics and Mass Spectrometry Studies
  • Advancements in Materials Engineering
  • Mitochondrial Function and Pathology
  • Human-Animal Interaction Studies
  • Bacillus and Francisella bacterial research
  • Medical Imaging Techniques and Applications
  • Biomedical Research and Pathophysiology
  • Imbalanced Data Classification Techniques

LMU Klinikum
2024

University of Lucerne
2024

Ludwig-Maximilians-Universität München
2020-2024

Statistisches Bundesamt
2021

University of St. Gallen
2017-2020

Emory University
2017-2019

Swiss Finance Institute
2018

Siemens (Germany)
2015

Max Planck Institute for Medical Research
2014

Max Planck Society
2014

Abstract We examine the effect of introduction Morningstar's Sustainability Rating in March 2016 on mutual fund flows. Exploiting this shock to availability sustainability information, we find strong evidence that retail investors shift money away from low‐rated and into high‐rated funds. An average receives between $ 4.1 million 10.1 higher net flows an suffers 1.0 5.0 lower than average‐rated during first year after publication Rating. Institutional react much more weakly

10.1111/eufm.12181 article EN European Financial Management 2018-05-22

Abstract Background Antidepressants are first-line medications for many psychiatric disorders. However, their widespread long-term use in some indications (e.g., mild depression and insomnia) is concerning. Particularly older adults with comorbidities polypharmacy, who more susceptible to adverse drug reactions, the risks benefits of treatment should be regularly reviewed. The aim this consensus process was identify explicit criteria potentially inappropriate antidepressant (indicators)...

10.1186/s12916-024-03397-w article EN cc-by BMC Medicine 2024-05-13

: media-1vid110.1542/5849572227001PEDS-VA_2018-2516Video Abstract OBJECTIVES: For decades, infants with Duarte galactosemia (DG) have been identified by newborn screening (NBS), but whether they should be treated dietary restrictions of galactose has remained unknown. To clarify, we conducted a study and developmental outcomes in 206 children DG (case patients) 144 controls, all whom were 6 to 12 years old.We recruited case patients from states where NBS; unaffected siblings served as...

10.1542/peds.2018-2516 article EN PEDIATRICS 2018-12-28

Vaccination is the most important preventive measure for protection against infectious diseases in humans and companion animals. Nevertheless, scepticism about safety importance of vaccines increasing human veterinary medicine. Although owner attitudes towards vaccination have been investigated cats, there are no similar studies dogs. The goals this study were therefore to investigate status dogs Germany, determine compliance with identify factors that play a role owners' decisions their...

10.1371/journal.pone.0238371 article EN cc-by PLoS ONE 2020-08-27

while many drug groups are associated with falls in older people, less is known about absolute increases risk and how these risks vary across different of drugs or individuals.we conducted a population based nested case-control study among people aged ≥65 years the Scottish regions Tayside Fife. Cases were individuals hospitalised fracture between 2010 2020, to whom we matched up 10 controls. We examined relative as 'Fall-Risk-Increasing Drugs' (FRIDs), alone combination, younger (≥75 years)...

10.1093/ageing/afad079 article EN Age and Ageing 2023-06-01

A major challenge for third generation data mining and knowledge discovery systems is the integration of different tools services understanding, integration, preprocessing, mining, evaluation deployment, which are distributed across network computer systems. In this paper we outline how an intelligent assistant that intended to support end-users in difficult time consuming task designing KDD-Workflows out these can be built. The should user checking correctness workflows, understanding goals...

10.5167/uzh-25868 article EN 2009-09-01

The molecular chaperone ClpB/Hsp104, a member of the AAA+ superfamily (ATPases associated with various cellular activities), rescues proteins from aggregated state in collaboration DnaK/Hsp70 system. ClpB/Hsp104 forms hexameric, ring-shaped complex that functions as tightly regulated, ATP-powered disaggregation machine. Highly conserved and essential arginine residues, often called fingers, are located at subunit interfaces complex, which also harbor catalytic sites. Several proteins,...

10.1074/jbc.m114.608828 article EN cc-by Journal of Biological Chemistry 2014-09-25

The present study deals with variation in the use of lexico-grammatical patterns and emphasizes need to embrace individual variation. Targeting pattern that’s adj (as right , nice or okay ) as a case study, we tailor-made Python script systematically retrieve grammatical semantic information about all instances this construction BNC2014 well sociolinguistic enabling us social among speakers who have used pattern. dataset amounts 4,394 tokens produced by 445 using 159 adjective types 931...

10.3389/frai.2020.547531 article EN cc-by Frontiers in Artificial Intelligence 2021-01-26

We examine the effect of introduction Morningstar's Sustainability Rating in March 2016 on U.S. mutual equity fund flows. Using panel regressions, propensity score matching, and an event study methodology we find strong robust evidence that retail investors shift money away from low-rated into high-rated funds. The is driven by publication Morningstar not due to a general attractiveness sustainable Institutional do react Rating. estimate average receives between $ 4.1 million 10.1 higher...

10.2139/ssrn.3068724 article EN SSRN Electronic Journal 2017-01-01

There has been increasing interest in identifying genes within the human genome that influence multiple diverse phenotypes. In presence of pleiotropy, joint testing these phenotypes is not only biologically meaningful but also statistically more powerful than univariate analysis each separate phenotype accounting for testing. Although many cross-phenotype association tests exist, majority such methods assume samples composed unrelated subjects and therefore are applicable to family-based...

10.1002/gepi.22116 article EN Genetic Epidemiology 2018-02-20

The molecular causes of idiopathic scoliosis have not yet been clarified to any appreciable extent and are probably heterogeneous. occurrence scolioses in congenital diseases the connective tissue points changes metabolism. Collagen is most essential structural component bone. It was aim our investigations examine synthesis collagen Types I II order identify a possible defect. In woman patient examined by authors, pathologically changed alpha-chain Type found as probable cause this...

10.1055/s-2008-1051634 article EN Zeitschrift für Orthopädie und ihre Grenzgebiete 2008-03-18
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