A5043966207- Enzyme Structure and Function
- Protein Structure and Dynamics
- Origins and Evolution of Life
- Dendrimers and Hyperbranched Polymers
- Radiation Therapy and Dosimetry
- Molecular Communication and Nanonetworks
- Photosynthetic Processes and Mechanisms
- Radiation Dose and Imaging
- Metalloenzymes and iron-sulfur proteins
- Advanced Radiotherapy Techniques
- Electrochemical Analysis and Applications
- Advanced Drug Delivery Systems
- Protein Kinase Regulation and GTPase Signaling
- Cystic Fibrosis Research Advances
- Advanced biosensing and bioanalysis techniques
- Legume Nitrogen Fixing Symbiosis
- RNA and protein synthesis mechanisms
- Electrochemical sensors and biosensors
- Hemoglobin structure and function
- HVDC Systems and Fault Protection
- Crystallization and Solubility Studies
- Crystallography and molecular interactions
- Protein purification and stability
- Porphyrin Metabolism and Disorders
- Advanced Proteomics Techniques and Applications
Terna (Italy)
2022
University of Modena and Reggio Emilia
2019
University of Trento
2015-2017
Instituto di Biofisica
2015
University of Genoa
2012-2014
Artificial cells capable of both sensing and sending chemical messages to bacteria have yet be built. Here we show that artificial are able sense synthesize quorum signaling molecules can chemically communicate with V. fischeri, harveyi, E. coli, P. aeruginosa. Activity was assessed by fluorescence, luminescence, RT-qPCR, RNA-seq. Two potential applications for this technology were demonstrated. First, the extent which could imitate natural quantified a type cellular Turing test. in response...
Research Article| December 01, 2016 Metal Catalysts and the Origin of Life Luca Belmonte; Belmonte 1CIBIO, University Trentovia Sommarive 9, Povo, ItalyE-mail: luca.belmonte@unitn.it Search for other works by this author on: GSW Google Scholar Sheref S. Mansy * *mansy@science.unitn.it Author Article Information Publisher: Mineralogical Society America First Online: 13 Jul 2017 Online Issn: 1811-5217 Print 1811-5209 © Elements (2016) 12 (6): 413–418....
Based on UV-Vis, NMR, and EPR spectroscopies DFT molecular dynamics calculations, a model prebiotic [2Fe-2S] tripeptide was shown to accept donate electrons. Duplications of the sequence led protoferredoxin with increased stability. primitive peptides may have contributed formation contemporary ferredoxins.
Model prebiotic dipeptide sequences were identified by bioinformatics and DFT molecular dynamics calculations. The peptides then synthesized evaluated for metal affinity specificity. Cysteine containing dipeptides not associated with affinities that followed the Irving-Williams series but did follow concentration trends found in seawater.
A new R tool is described that rapidly identifies, ranks, and clusters sequence patterns coordinated to metallocofactors. This tool, PdPDB, fills a void because, unlike currently available tools, PdPDB searches through sequences with metal coordination as the primary determinant can identify consisting of amino acids, nucleotides, small molecule ligands at once. was tested by analyzing structures coordinate Fe2+/3+, [2Fe-2S], [4Fe-4S], Zn2+, Mg2+ cofactors. confirmed previously identified...
The recent application of Mass Spectrometry (MS) to Nucleic Acid Programmable Protein Array (NAPPA) technique for proteins identification by non-classical methods leads the needs more sophisticated algorithm peak recognition.NAPPA allows functional be synthesized in situ directly from printed cDNAs but faces difficulty generated presence master mix and lysate molecules peaks appearing as background overall spectra.A wide range tools are available analyze conventional mass spectra...
Dbl family Rho guanine nucleotide exchange factors (RhoGEFs) play a central role in cell biology by catalyzing the of guanosine 5′-triphosphate for 5′-diphosphate (GDP) on RhoA. Insights into oncogenic constitutive activity Lbc RhoGEF were gained analyzing structure and dynamics protein different functional states comparison with close homologue, leukemia-associated RhoGEF. Higher intrinsic flexibility, less dense extended network, stable allosteric communication pathways Lbc, compared to...
X-ray atomic structure of recombinant Hell's gate globin I (HGbI) from Methylacidophilum infernorum was calculated the diffraction data two different types crystals: obtained by classical hanging drop and LB nanotemplate method under same crystallization conditions. After accurate comparison crystallographic parameters electron density maps structures they appears to be quite similar, while quality crystals grown higher then those method. Indeed, resolution crystal 1.65 Å, showed only 3.2 Å...
This work is a status report of the job in progress finalized to estimation dose distribution inside head patient undergoing high resolution CT (Computed Tomography) for diagnosis pathologies related inner ear. Geant4 (GEometry ANd Tracking) has been used simulate and propagate particles human tissues. The ear very complex structure, particular section includes many small structures, which are located compact region (a few square centimeters), them have dimensions below millimeter....
In the context of ongoing energy transition, electrical power system will undergo a significant infrastructure and management evolution. The progressive decarbonisation with decommissioning synchronous generation units, in face massive penetration from Renewable Energy Sources (RES), requires new challenges for global Transmission System Operators (TSOs). Main issues are related to sharply decreasing inertia, lowering short-circuit levels, reduction voltage regulation reactive systems,...