- Heart Failure Treatment and Management
- Potassium and Related Disorders
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Healthcare Systems and Public Health
- Electrolyte and hormonal disorders
- Cardiac pacing and defibrillation studies
- Blood Pressure and Hypertension Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Protease and Inhibitor Mechanisms
- Clusterin in disease pathology
- Breast Cancer Treatment Studies
- Congenital Diaphragmatic Hernia Studies
- Chemotherapy-induced cardiotoxicity and mitigation
- HER2/EGFR in Cancer Research
- Advanced Antenna and Metasurface Technologies
- Dialysis and Renal Disease Management
- Coronary Interventions and Diagnostics
- Cancer-related cognitive impairment studies
- Cardiovascular and exercise physiology
- Cardiac Structural Anomalies and Repair
- Acute Ischemic Stroke Management
- Cardiac Health and Mental Health
- Cancer Treatment and Pharmacology
Hospital Universitari de Girona Doctor Josep Trueta
2019-2025
Hospital Universitari Sant Joan D'Alacant
2019-2024
Hospital Del Mar
2019-2021
Abstract Aims Information about current use of finerenone in patients with heart failure (HF) clinical practice is scarce, and its effectiveness scarce. We aim to assess both the baseline profile prognostic role HF, irrespective ejection fraction. Methods results The study a multicentre, observational registry, including regional tertiary hospitals. registry incorporates contributions from cardiology, internal medicine, nephrology departments, ensuring comprehensive data collection. Patients...
Abstract Aims The outpatient diuretic dose is a marker of resistance and prognosis in chronic heart failure (HF). Still, the impact preadmission on efficiency (DE) acute HF not fully known. Methods results We conducted an observational prospective study. All patients admitted for treated with intravenous at least one criterion congestion admission were evaluated. Decongestion [physical examination, hemoconcentration, N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) change, lung...
Introduction and Objectives: Dyspnea is the most common symptom among hospitalized patients with heart failure (HF) but besides dyspnea questionnaires (which reflect subjective patient sensation are not fully validated in HF) there no measurable physiological variables providing objective assessment of a setting acute HF patients. Studies performed respiratory suggest that measurement electromyographic (EMG) activity muscles surface electrodes correlates well dyspnea. Our aim was to test...
Diuretic resistance (DR) is a common condition during heart failure (HF) hospitalization, and related to worse prognosis. Although the risk factors for DR HF hospitalization are widely described, we do not know whether of chronic could be predicted admission.We conducted multicenter, prospective observational study between July 2017 2019. All patients admitted acute with intravenous diuretic treatment at least one criterion congestion on admission were invited participate. Patients renal...
Abstract Funding Acknowledgements None. Introduction The prevalence of atrial fibrillation (AF) and ischaemic heart disease (IHD) increases with age, conditioning a complex relatively frequent scenario in clinical practice. Our objective was to know the variables associated prognosis cohort patients AF IHD our country after year follow-up. Methods An observational, prospective multicentre study that included Spain. Baseline, clinical, laboratory echocardiographic characteristics were...
Abstract Funding Acknowledgements None. Introduction The selection of antithrombotic treatment in patients with ischaemic heart disease (IHD) and atrial fibrillation (AF) represents a challenge when trying to balance haemorrhagic risk. However, there is little "real-life" data on the selected its short long-term prognosis. Methods A Prospective multicentre study that includes IHD [acute coronary syndrome (ACS) or chronic (CCS)] AF admitted 13 Spanish centres. objective describe...
Albuminuria could potentially emerge as a novel marker of congestion in acute heart failure. However, the current evidence linking albuminuria and patients with congestive failure (CHF) remains somewhat scarce. This study aimed to evaluate prevalence cohort CHF, identify independent factors associated analyse correlation different parameters. is subanalysis Spanish Cardiorenal Registry, which we enrolled 864 outpatients value urinary albumin:creatinine ratio (UACR) at first visit. The median...
Introduction and Objectives: A comprehensive assessment of congestion, including circulating biomarkers, is recommended in patients with acute heart failure. The biomarkers natriuretic peptides (NPs) carbohydrate antigen-125 (CA125) could be useful for congestion ambulatory chronic failure (CHF), but there only limited information about their applicability this context. Therefore, study aimed to examine the association plasma CA125 NP levels clinical ultrasound parameters CHF. Methods: This...
586 Background: We previously conducted a phase II study to evaluate NEO regimen of docetaxel/carboplatin/trastuzumab (TCH) in 48 pts with clinical stage II-IIIB HER2 overexpressing breast cancer. The pCR rate was 42%. current sought retrospectively investigate the correlation between total protein expression (H2T) and homodimers (H2D), by novel quantitative assay, pre-therapy tumor specimens from this trial percent change size (ΔTS) following ddTCH therapy. Methods: Pre-therapy...
Abstract Background Elderly patients are usually under-represented in randomized controlled trials, therefore there is less data providing prognostic information for this particular group. NSTEMI clinical practice guidelines indicate that older should receive the same therapeutic strategy than younger patients. Methods Observational retrospective study including 8771 admitted acute coronary syndrome two tertiary referral hospitals between 2003 and 2017: 5673 (64.3%) 3098 STEMI (35.7%). 999...
Abstract Background Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) remains a challenge in cardiology clinical practice. 2016 European Society of Cardiology Working Group position paper (ESC-WGPP) recommend to treat them as the rest myocardial infarctions, mainly dual antiplatelet therapy (DAT), beta blockers, Angiotensin Converter Enzyme Inhibitors (ACEI), and statins. The aim this study is analyse use optimal medical treatment (OMT) ischemic heart disease (IHD) on...
Abstract The new European Society of Cardiology guideline for ST-segment elevation myocardial infarction recommends that left and right bundle branch block should be considered equal recommending urgent angiography in patients with suspected infarction. This consideration is not taken into account the management coronary syndrome without ST (NSTEMI). We evaluate evolution acute long-term block. Patients methods included 8771 admitted to two tertiary hospitals between 2003 2017 an syndrome,...
Abstract Funding Acknowledgements none OnBehalf Background Chemotherapy cardiotoxicity is a serious complication in breast and haematological malignancies. However, its primary prevention with angiotensin converting enzyme inhibitors (ACEI)/angiotensin II receptor antagonists (ARB) and/or beta-blockers (BB) medication has discrepant results. The aim of our study was to establish whether using these treatments prevents any them superior the others. Methods A systematic review meta-analysis...
Abstract Background Previous studies using experimental models and clinical retrospective samples have pointed to a potential role of glycosylated apolipoprotein J (ApoJ-Glyc) as marker for the early detection myocardial ischaemia. Ischaemia induces intracellular accumulation non-glycosylated ApoJ that mirrors reduction in ApoJ-Glyc serum levels patients presenting with ST-segment elevation infarction (STEMI). Purpose The EDICA (Early Detection Myocardial Suspected Acute Coronary Syndromes...
Abstract Background The timing for the initiation of dual antiplatelet treatment (DAPT) in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS) is controversial and 2020 ESC guidelines suppressed recommendation routine pre-treatment. aim our study was to assess effect pretreatment on clinical outcomes according available evidence. Methods We conducted a meta-analysis main studies P2Y12 receptor inhibitors NSTE-ACS. After systematic review, we included four randomized...