- Viral Infections and Vectors
- Rock Mechanics and Modeling
- Geomechanics and Mining Engineering
- Mosquito-borne diseases and control
- Geoscience and Mining Technology
- Viral Infections and Outbreaks Research
- Colorectal Cancer Surgical Treatments
- Coal Properties and Utilization
- Mining and Resource Management
- Physical Unclonable Functions (PUFs) and Hardware Security
- Tailings Management and Properties
- Cell Image Analysis Techniques
- Respiratory viral infections research
- Animal Disease Management and Epidemiology
- Drilling and Well Engineering
- Grouting, Rheology, and Soil Mechanics
- Landslides and related hazards
- Integrated Circuits and Semiconductor Failure Analysis
- DNA and Biological Computing
- Influenza Virus Research Studies
- Advanced Steganography and Watermarking Techniques
- Plant and Fungal Interactions Research
- Stoma care and complications
- vaccines and immunoinformatics approaches
- Tunneling and Rock Mechanics
Guizhou Minzu University
2021-2024
Guizhou University
2008-2024
RWTH Aachen University
2017-2018
Fraunhofer Institute for Applied and Integrated Security
2017
Dongguan People’s Hospital
2013
National Institute for Viral Disease Control and Prevention
2009-2012
Halliburton (United Kingdom)
2012
Panyu Hospital of Chinese Medicine
2012
Central South University
2012
South China Normal University
2011
The discovery of an emerging viral disease, severe fever with thrombocytopenia syndrome (SFTS), caused by SFTS virus (SFTSV), has prompted the need to understand pathogenesis SFTSV. We are unique in establishing infectious model C57/BL6 mice, resulting hallmark symptoms and leukocytopenia. Viral RNA histopathological changes were identified spleen, liver, kidney. However, replication was only found which suggested spleen be principle target organ Moreover, number macrophages platelets...
The development of new therapeutic targets and strategies to control highly pathogenic avian influenza (HPAI) H5N1 virus infection in humans is urgently needed. Broadly cross-neutralizing recombinant human antibodies obtained from the survivors provide an important role immunotherapy for definition critical epitopes vaccine development.We have characterized two baculovirus-expressed (rhAbs), AVFluIgG01 AVFluIgG03, generated by screening a Fab antibody phage library derived patient recovered...
Aiming at the problem of coal face failure lower seam under influence repeated mining in close seams, with working 17,101 as a background, samples mechanics test clarified strength characteristics mining, through similar simulation experiments, development stable roof structure and surrounding rock cracks seams are further explored. And based on this, establish model to comprehensively analyze multiple structural instabilities stability face. Finally, numerical is used supplement verify...
This study aims to effectively solve the problem of destruction coal roof and floor overlying rock after mining protective layer, determines whether gas in protected layer can be released. We do this based on engineering background Weng’an Coal Mine; research analysis movement rocks; evolution cracks pressure relief characteristics layer; through theoretical similar simulation experiments. Through numerical simulation, it was found that depressurized due decompression rate 0.2–0.8. In...
In order to effectively solve the problem of gas concentration overrun in upper corner goaf and tailentry during mining panel 9303 Anshun Coal Mine, based on advantages controllable trajectory wide coverage area directional drilling technology, high long boreholes are arranged extract pressure relief gas. Firstly, principle borehole drainage technology is introduced, fracture evolution overlying strata obtained through using numerical simulation, theoretical calculation, field practice,...
Due to their complex geological structure, it is difficult systematically analyze the surface subsidence of coal mines in southwest China, and factors that cause are also different from other mines. Focusing on problem caused by mining China’s mines, a grade evaluation system for constructed based analytic hierarchy process, ten indicators established perspectives disturbance structure. A matter–element model extension theory cloud then constructed. mine Anshun, Guizhou, taken as an example...
Abstract Background Hantaan virus (HTNV) is the causative agent of most severe form a rodent-borne disease known as hemorrhagic fever with renal syndrome (HFRS). A safe and effective HTNV vaccine needed. Vaccination DNA constructs expressing fused antigen bioactive factors, has shown promising improvement immunogenicity for viral agents in animal models, but effect fusion strategy on not been investigated. Results plasmids encoding nucleocapsid protein (N) glycoprotein (Gn Gc) to...
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