A5037343636- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- COVID-19 and healthcare impacts
- Intraperitoneal and Appendiceal Malignancies
- Trauma and Emergency Care Studies
- Cervical Cancer and HPV Research
- Sarcoma Diagnosis and Treatment
- Assisted Reproductive Technology and Twin Pregnancy
- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Endometriosis Research and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Advances in Oncology and Radiotherapy
- Minimally Invasive Surgical Techniques
- Cancer Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Colorectal Cancer Surgical Treatments
- Estrogen and related hormone effects
- Salivary Gland Tumors Diagnosis and Treatment
- Uterine Myomas and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Prenatal Screening and Diagnostics
- Congenital limb and hand anomalies
- Cancer Risks and Factors
- Angiogenesis and VEGF in Cancer
Hospital Universitario La Paz
2020-2024
University of Birmingham
2020-2021
NIHR Birmingham Biomedical Research Centre
2021
Yorkshire Cancer Research
2021
Urology Foundation
2021
Association for Cancer Surgery
2021
Universidad Autónoma de Madrid
2021
Hospital La Paz Institute for Health Research
2021
Stryker (United Kingdom)
2020
Pfizer (United Kingdom)
2020
Serum levels of procalcitonin and C-reactive protein (CRP) have been used to predict anastomotic leakage after colorectal surgery, but information is scarce in advanced ovarian cancer (AOC) surgery with bowel resection. This study aimed assess the predictive value CRP detecting AOC The also determine optimal postoperative reference values best day for evaluating these markers.
Objective: To evaluate the oncological outcomes of patients with low-volume metastasis compared to those macrometastasis and negative nodes in endometrial cancer. Methods: A single institutional retrospective study was carried out, which included all cancer who underwent surgical treatment between January 2007 December 2016. We analyzed progression-free survival (PFS) overall (OS) after sentinel node biopsy full nodal staging according their final pathological status, focusing on impact size...
Introduction Recent evidence has shown adverse oncological outcomes when minimally invasive surgery is used in early-stage cervical cancer. The objective of this study was to compare disease-free survival patients that had undergone radical hysterectomy and pelvic lymphadenectomy, either by laparoscopy or laparotomy. Methods We performed a multicenter, retrospective cohort with cancer stage IA1 lymph-vascular invasion, IA2, IB1 (FIGO 2009 classification), between January 1, 2006 December 31,...
To evaluate the role of sentinel lymph node biopsy (SLNB) to avoid staging lymphadenectomies by detecting nodal metastasis in intermediate- and high-risk endometrial cancer (EC).A single institutional retrospective study was performed including all patients with EC who underwent surgical between January 2012 December 2019. Patients disseminated disease detected on imaging techniques or at time surgery were excluded. evaluable if they SLNB pelvic (PLD) paraaortic (PALD) dissection. We...
The objective of this study was to evaluate the efficacy one-step nucleic acid amplification (OSNA) for detection sentinel lymph node (SLN) metastasis compared standard pathological ultrastaging in patients with early-stage endometrial cancer (EC). A total 526 SLNs from 191 EC were included study, and 379 (147 patients) evaluated by both methods, OSNA ultrastaging. central 1 mm portion each subjected semi-serial sectioning at 200 μm intervals examined hematoxylin–eosin immunohistochemistry...
Internal mammary chain (IMC) is one of the main local lymph drainages in breast cancer. However, internal sentinel node biopsy (IMC-SLNB) not always performed. The purpose this research to evaluate outcomes IMC-SLNB our institution from 2008 2014. We analyzed 1346 women with Six-hundred twenty-two biopsies were carried out, out ten IMC territory. Adjuvant radiotherapy area was added when positive. feasible, it may change tumour stage, modify adjuvant therapy and prognosis selected patients.
(1) Background: To establish similarities in the risk of axillary lymph node metastasis between different groups women with breast cancer according to immunohistochemical (IHC) parameters. (2) Methods: Data was collected retrospectively, from 2000 2013, 1058 node-positive tumours. All patients were divided St Gallen 2013 criteria and IHC features. The proportion involvement (pN > pN0; pN pN1mi; pN1) calculated for each group. Similarities nodal dissemination explored by cluster analysis...
The main objective was to analyze the rate of bilateral sentinel lymph node (SLN) detection in endometrial cancer using indocyanine green (ICG) as a unique tracer compared Technetium99 + ICG. As secondary objectives, we analyzed drainage pattern and factors that might affect oncological outcomes. A case-control ambispective study carried out on consecutive patients at our center. Data SLN biopsy with ICG collected prospectively were retrospective data use double-tracer technique including In...
The benefit of adjuvant radiotherapy (RT) after radical hysterectomy in patients with cervical cancer remains controversial. aim this study was to determine the impact on survival RT according Sedlis criteria. Patients early-stage who underwent between 2005 and 2022 at a single tertiary institution were included. A multivariate analysis performed determinate if an independent prognostic factor for recurrence or death. We also analyzed whether there statistically significant difference...
The SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) pandemic changed the distribution of healthcare resources, leading in many cases to suspension all non-essential treatments and procedures representing a challenge for medical professionals. objective this study was evaluate whether clinical protocols gynecologic oncology care were modified as result assess surgeons' perceptions regarding management cancers".Data collected through an anonymous voluntary survey sent via email...
The benefit of adjuvant radiotherapy (RT) after radical hysterectomy in patients with cervical cancer remains controversial. aim this study was to determine RT's impact on survival accordance Sedlis criteria. Patients early-stage undergoing between 2005 and 2022 at a single tertiary care institution were included. A multivariate analysis performed determinate if RT an independent prognostic factor for recurrence or death. We also analysed whether there statistically significant difference...
Granulosa cell tumors are diagnosed in stage I 95% of cases, with a rate recurrence as high 10–64%.[1][1] The most common management granulosa tumor is surgical treatment, achieving no visible residual disease because the presence after surgery seems to be
The objective of this study was to evaluate the efficacy one-step nucleic acid amplification (OSNA) for detection sentinel lymph node (SLN) metastasis compared standard pathological ultrastaging in patients with early-stage endometrial cancer (EC). A total 526 SLNs from 191 EC were included study. 379 (147 patients) evaluated by both methods, OSNA and ultrastaging. central 1-mm portion each subjected semi-serial sectioning at 200-μm intervals examined hematoxylin-eosin...
Although bladder dysfunction is the most commonly reported complication after radical hysterectomy, there are other significant complications associated with cervical cancer surgery that have received less attention in literature.This study aims to investigate frequency of non-functional related hysterectomy and identify significantly risk factors their occurrence.A retrospective was conducted on consecutive patients diagnosed early-stage who underwent at La Paz University Hospital between...
<h3>Introduction/Background</h3> To evaluate the main risk factors for recurrence in endometrial cancer and to assess prognostic impact of treatment strategies this setting. <h3>Methodology</h3> We performed a single institutional retrospective study women with who underwent surgical between January 2007 December 2019. analyzed pattern tumor recurrence, histological related disease-free overall its relation received. Kaplan-Meier curves were used estimate survivals. <h3>Results</h3> A total...
<h3>Introduction/Background</h3> Minimally invasive paraaortic lymphadenectomy can be performed using two different approaches: transperitoneal and extraperitoneal. The route offers difficulties with the mobilization retraction of small bowel sigmoid colon, worsening exposure surgical field. On contrary, extraperitoneal approach provides an excellent anatomical exposure, even in patients obesity, reducing considerably adhesion rate, as well intraoperative complications. It also a greater...
<h3>Introduction/Background</h3> Background: Ovarian cancer relapse is a challenging situation that requires multidisciplinary approach. Debulking in secondary or subsequent relapses should be considered highly selected cases, based on performance status, tumour biology and location of recurrence, as long complete resection can achieved. <h3>Methodology</h3> In this video, we present case ovarian which tertiary debulking performed. <h3>Results</h3> This 55-year-old patient, diagnosed with...