A5016598785- Covalent Organic Framework Applications
- BRCA gene mutations in cancer
- Parkinson's Disease Mechanisms and Treatments
- Mitochondrial Function and Pathology
- Advanced Nanomaterials in Catalysis
- Ovarian cancer diagnosis and treatment
- Advanced Photocatalysis Techniques
- DNA Repair Mechanisms
- CRISPR and Genetic Engineering
- Genetic Neurodegenerative Diseases
- Metal-Organic Frameworks: Synthesis and Applications
- Cancer Genomics and Diagnostics
- Carbon dioxide utilization in catalysis
South China University of Technology
2024
Gene Tech (China)
2020-2022
Sun Yat-sen University
2022
Guangdong University of Technology
2021
This review summarized the recent advances made in task-specific design and synthesis of metalloporphyrin-based porous organic polymers (POPs) their functionalization for conversion CO 2 into cyclic carbonates.
Abstract Mitochondria are a culprit in the onset of Parkinson’s disease, but their role during disease progression is unclear. Here we used Cox proportional hazards models to exam effect variation mitochondrial genome on longitudinal cognitive and motor over time 4064 patients with disease. Mitochondrial macro-haplogroup was associated reduced risk discovery replication population. In combined analysis, super J, T, U# had 41% lower P = 2.42 × 10−6 compared those H. Exploratory analysis...
Schiff-base covalent organic frameworks (COFs), recognized for their designable structures, abundant modification sites, and robust stability, are considered ideal platforms constructing biomimetic enzymes. This study introduces a strategy the construction of copper-metalated based on N–M–O coordination environment peroxidases' metal amino acids. A enzyme framework, Cu-COF-TAPT-DHTA, was synthesized by postmetalation with copper. framework catalyzes oxidation 3,3′,5,5′-tetramethylbenzidine...
Cancer risks vary in different BRCA1/2 mutations. We are interested identifying regions associated with elevated/reduced of breast/ovarian cancers the Chinese population and comparing previously reported Caucasian-based cancer cluster (OCCR/BCCR). also aim to characterize distribution estimate recurrent mutations.A total 3,641 cancer-free women 4,278 female patients were included study. Germline status was detected amplicon-based next-generation sequencing. calculated odds ratio (OR) breast...
Abstract Background Cancer risks vary in different BRCA1/2 mutations. Previous studies based on Caucasian population have identified regions associated with elevated/reduced of breast/ovarian cancers. Since ethnic differences are known to affect mutation spectra, we interested defining Chinese-specific ovarian/breast cancer cluster (OCCR/BCCR) and comparing previously reported Caucasian-based regions. We also aim characterize the distribution estimate Chinese recurrent Methods 7,919 (3,641...