A5076824622- Single-cell and spatial transcriptomics
- Cell Image Analysis Techniques
- 3D Printing in Biomedical Research
- Visual Attention and Saliency Detection
Understanding cellular architectures and their connectivity is essential for interrogating system function dysfunction. However, we lack technologies mapping the multiscale details of individual cells in human organ-scale system. We developed a platform that simultaneously extracts spatial, molecular, morphological, information from same brain. The includes three core elements: vibrating microtome ultraprecision slicing large-scale tissues without losing (MEGAtome), polymer hydrogel-based...
Abstract Understanding cellular architectures and their connectivity is essential for interrogating system function dysfunction. However, we lack technologies mapping the multi-scale details of individual cells in human organ-scale system. To address this challenge, developed a platform that simultaneously extracts spatial, molecular, morphological, information from same brain, by integrating novel chemical, mechanical, computational tools. The includes three key tools: (i) vibrating...