A5078146953- Fetal and Pediatric Neurological Disorders
- Prenatal Screening and Diagnostics
- Pediatric Urology and Nephrology Studies
- Parvovirus B19 Infection Studies
- Cytomegalovirus and herpesvirus research
- Assisted Reproductive Technology and Twin Pregnancy
- Urological Disorders and Treatments
- Toxoplasma gondii Research Studies
- Spinal Dysraphism and Malformations
- Congenital Diaphragmatic Hernia Studies
- Herpesvirus Infections and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Ureteral procedures and complications
- Neonatal and fetal brain pathology
- Cerebrospinal fluid and hydrocephalus
- Autopsy Techniques and Outcomes
- Intestinal Malrotation and Obstruction Disorders
- Vaccine Coverage and Hesitancy
- Pregnancy and preeclampsia studies
- Tumors and Oncological Cases
- Neonatal Respiratory Health Research
- Gastrointestinal disorders and treatments
- Influenza Virus Research Studies
- Preterm Birth and Chorioamnionitis
- Grief, Bereavement, and Mental Health
Università Cattolica del Sacro Cuore
2015-2025
Agostino Gemelli University Polyclinic
2006-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2025
IRCCS Humanitas Research Hospital
2019
National Center for Oncological Hadrontherapy
2019
Azienda Ospedaliero Universitaria Maggiore della Carita
2016
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2016
Catholic University of America
2000-2013
Charité - Universitätsmedizin Berlin
2012
Walter de Gruyter (Germany)
2012
Summary. A linear‐array pulsed Doppler duplex has been used to study third‐trimester flow velocity waveforms (FVW) in the descending thoracic aorta of 98 normal and 20 severely growth‐retarded fetuses. Waveforms have normalized (frequency index profile; FIP) remove effect angle insonation so allow comparison at different gestational ages with complicated pregnancies. There is an increase end‐diastolic velocities advancing age indicating a reduction placental resistance. The fetuses showed...
Matthew-Wood, Spear, PDAC or MCOPS9 syndrome are alternative names used to refer combinations of microphthalmia/anophthalmia, malformative cardiac defects, pulmonary dysgenesis, and diaphragmatic hernia. Recently, mutations in STRA6, encoding a membrane receptor for vitamin A-bearing plasma retinol binding protein, have been identified such patients. We performed STRA6 molecular analysis three fetuses one child diagnosed with Matthew-Wood siblings where two adult living brothers affected...
To evaluate the reliability of prenatal invasive and non-invasive diagnosis by a retrospective analysis on single centre cohort pregnancies with suspected toxoplasmosis from 1978 to 2015, mostly treated Spiramycin/Cotrimoxazole (Sp/C) protocol. We discussed options all women; 345 (32,4%) underwent amniocentesis, execution inoculation tests in mice until 2006 PCR since 1996. All women were offered monthly detailed ultrasound (US) signs Congenital Toxoplasmosis (CT), mainly ventriculomegaly,...
Seventeen cases of congenital cystic adenomatoid malformation the lung (CCAM) are reported. They were followed up over a period 1 month to 15 years. Diagnosis was made by prenatal ultrasound. Our purpose evaluate fetal-neonatal outcome and prognostic elements observable through ultrasound techniques, compare all types CCAM. The observed ranged from total resolution postnatal spontaneous regression lesion, complications due presence nonimmune fetal hydrops (NIFH), intrauterine death necessity...
Cytomegalovirus (CMV) infection during pregnancy poses significant maternal and fetal health risks. Valacyclovir, an antiviral drug, has been explored as a therapeutic option for managing primary CMV infections in pregnant women. This study investigates the effects of valacyclovir therapy on immune response maturation against CMV, antibody levels, viral replication treatment. We conducted retrospective observational involving women diagnosed with presenting utero who received high-dose (8...
Abstract Objective: The purpose of this study is to define the role foetal magnetic resonance imaging (MRI) in evaluating cerebral ischaemic-haemorrhagic lesions and extension parenchymal injuries. Study design: From September 2006 2010, 271 MRI have been performed on cases referred us for ultrasound suspect brain abnormalities or cytomegalovirus infection Toxoplasma serum conversion. Foetal was with a 1.5-T magnet system without mother sedation. Results: detected 14 foetuses, consisting 5%...
Objective. To show the validity of prenatal invasive surgical intervention when a fetal ovarian cyst is diagnosed, compared to wait and see attitude, in order avoid possible postnatal complications.Patients. Fourteen cases intra-abdominal cysts monitored our center between April 2005 November 2010. All were first diagnosed third trimester, for remainder pregnancy after delivery (2 months–3 years postnatally).Surgical intervention. Upon maternal cutaneous anesthesia performed...
<i>Objective:</i> To evaluate the efficacy of transabdominal amnioinfusion on feto-neonatal and maternal morbidity mortality. <i>Methods:</i> We studied 71 patients with preterm premature rupture membranes (pPROM) at <26 weeks gestational age. Thirty-four were managed expectantly 37 underwent serial saline every 7 days in case persistent oligohydramnios. <i>Results:</i> Latency period pPROM delivery, week delivery (26.0 vs. 22.4, p < 0.001), neonatal...
There is weak evidence on the best treatment of pregnant women with Toxoplasma gondii infection to prevent vertical transmission fetus.We conducted a 28-year retrospective study aiming compare efficacy three therapeutic regimens [Spiramicyn alone (Spy) vs. Pyrimethamine-Sulfadiazine (P/S) Spiramicyn Trimethoprim-Sulfamethoxazole (Spy+TMP-SMX)] for prevention mother-to-fetus T. infection.170 were included: 58 (34.1%) had certain congenital toxoplasmosis (CT), 61 (35.9%) probable and 41...
We report a case of early diagnosis iodide-induced fetal hypothyroidism at 22 weeks gestation, confirmed 29 by cordocentesis and successfully treated intra-amniotically. The ultrasonographic feature was the presence two echogenic masses in neck; polyhydramnios absent. Mild diagnosed based on serum obtained percutaneous umbilical blood sampling gestation. persistence spite maternal thyroid improvement second 35 single injection intra-amniotic levothyroxine (250 μg) performed. serial...
Congenital chylous ascites (CCA) is a rare disease that results from maldevelopment of the intra-abdominal lymphatic system. Few cases have been described and no gold standard treatment has defined so far. Octreotide, somatostatin analogue, used for CCA, but always after failed conservative approach with fasting, total parenteral nutrition (TPN) or medium chain triglyceride (MCT) feeds. We report case newborn CCA treated by TPN octreotide period 15 days until abdominal distension was...
<b>Introduction</b> Prenatal detection of isolated ascites is a rare finding on ultrasound, usually suggestive an underlying pathology that may negatively impact the pregnancy and neonatal outcome. The purpose present study was to evaluate outcome primary in relation gestational age (GA) at diagnosis. <b>Materials Methods</b> Data were prospectively collected for fetuses with have been followed our center prenatal diagnosis therapy from 2004 2014. Patients divided group I when detected...
<b>Introduction</b> The aim of the study was to investigate perinatal outcome fetuses with hyperechogenic bowel (HB) in relation gestational age at diagnosis. <b>Materials and Methods</b> This is a retrospective observational fetal HB cases from 2002 2012. Patients were divided into three groups according trimester For each group, data ultrasound examination, medicine investigations, intrapartum cares, neonatal obtained. <b>Results</b> A diagnosis made 279 among them 17 (6%) during first...
Abstract Background Toxoplasmosis is a parasitic infection caused by Toxoplasma gondii and responsible for gestational congenital infections worldwide. The current standard therapy based on the administration of Spiramycin to prevent trans‐placental transmission. Other therapies are being studied reduce rates foetal transmission symptomatic infection. Objectives We report our long‐standing experience in maternal toxoplasmosis treatment using combination Spiramycin–Cotrimoxazole, assessing...
Objective: The aim of this study was to evaluate the presence and severity neurological cognitive impairment at 2 years age in 16 infants (9 term born, 7 preterm mean gestation 33.6 weeks) with cerebral ventriculomegaly antenatal onset associated intraventricular haemorrhage.
The aim of this study was to assess visual function in 13 infants with evidence prenatal post haemorrhagic ventricular dilatation.Infants were assessed at 5, 12 and 24 months using a battery tests specifically designed various aspects infancy. Visual findings correlated several variables, including extent the lesion presence epilepsy.Abnormalities frequent (over 60%) our cohort age 2 years, ranging from isolated abnormal ocular movements severe abnormalities all assessed. most persistent...
Objective To analyse animal-related injury features treated in an emergency department. Methods Inspection of all reports concerning injuries the department 1998–1999, researched through non-codified diagnosis. Results A total 988 patients (1.66% annual visits) were for injuries. Prevalence causing agent was as follows: insects 53.1% (74.9% not identified), mammals 30.9%, marine fauna 7.4%, arachnids 7.1%, reptiles 0.51%, birds 0.51% and intestinal parasites 0.4%. Sex prevalence also noted:...