A5062441319- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- COVID-19 Clinical Research Studies
- Inflammasome and immune disorders
- Heparin-Induced Thrombocytopenia and Thrombosis
- Acute Myocardial Infarction Research
- Gout, Hyperuricemia, Uric Acid
- Cell Adhesion Molecules Research
- Healthcare Systems and Public Health
- Atherosclerosis and Cardiovascular Diseases
- Biomarkers in Disease Mechanisms
- Adipokines, Inflammation, and Metabolic Diseases
- Intramuscular injections and effects
- Heart Failure Treatment and Management
- Medication Adherence and Compliance
- Blood Pressure and Hypertension Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Cytokine Signaling Pathways and Interactions
- Long-Term Effects of COVID-19
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac Fibrosis and Remodeling
- Cardiovascular Health and Risk Factors
- SARS-CoV-2 and COVID-19 Research
- Platelet Disorders and Treatments
- Pharmaceutical Economics and Policy
Kazakh National Medical University
2020-2025
Central Clinical Hospital
2021
Several evidence show that elevated plasma levels of uric acid (UA) are associated with the increased risk developing atherothrombotic cardiovascular events. Hyperuricemia is a factor for endothelial dysfunction (ED). ED involved in pathophysiology atherothrombosis since dysfunctional cells lose their physiological, antithrombotic properties. We have investigated whether UA might promote by modulating tissue (TF)/TF pathway inhibitor (TFPI) balance finally changing characteristics cells....
The extensive use of therapeutic doses heparin to prevent thrombosis in critically ill patients with COVID-19 during the pandemic has led an increased incidence bleeding and heparin-induced thrombocytopenia (HIT). In addition, introduction AstraZeneca Johnson&Johnson vaccines against into clinical practice was associated development a rare but very severe, adverse thrombotic complication, vaccine-induced immune (VITT). Thrombotic complications VITT turned out be similar HIT both...
Although the cardiovascular (CV) polypill concept is not new and several guidelines state that a CV should be considered an integral part of comprehensive disease (CVD) prevention strategy, there are still some barriers to its implementation in real-world setting, mainly secondary prevention. As CNIC-polypill only one approved for patients with atherosclerotic CVD 27 countries worldwide, panel four discussants 30 participants from 18 conveyed virtual meeting on April 21, 2022, discuss key...
This article discusses relevant aspects in the treatment of patients with COVID-19. Up-to-date information about principles for administration statins, antithrombotics, and antiarrhythmics is presented. The authors addressed detail specific features reversing heart rhythm disorders coronavirus infection interaction antiarrhythmic antiviral drugs. Recommendations are provided outpatient inpatient antithrombotic therapy Issues drug discussed.
In this review, the authors describe new concept of MicroCLOTS (microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome) - proposed by Italian multidisciplinary team headed Ciceri F, et al. as cause atypical acute respiratory distress syndrome. etal. hypothesise that, in predisposed individuals, alveolar viral damage is followed an inflammatory reaction and microvascular pulmonary thrombosis. This progressive endothelial syndrome may also involve bed brain other vital...
Introduction: Cardiovascular disease (CVD) is a leading cause of mortality worldwide. The early post-hospitalization period following COVID-19 infection critical due to high incidences rehospitalization and deaths. Aim: To study the impact CVD on first 3 months after hospitalization for COVID-19. Methods: An international registry "ACTIV SARS-CoV-2" (NCT04492384) was established characterize course in Eurasian region included 7 countries. presented subanalysis used data patients hospitalized...
8 1 РЕПРИНТ (Алматы), №5 (191), 2018 ЭНДОКРИНОЛОГИЯ Модератор экспертного совета: Даньярова Л.Б., к.м.н., зав.кафедрой внутренних болезней с курсом эндокринологии Департамента послевузовского и дополнительного образования НИИ кардиологии МЗ РК (НИИ КиВБ МЗ).Состав 1. Нурбекова А.А., д.м.н., профессор кафедры КазНМУ им.С.Д.Асфендиярова; 2. Кабулбаев К.А., №3 3. Раисова А.М., заведующая отделением терапии МЗ; 4. Базарова А.В., доцент ФНПР ДО АО «Медицинский Университет Астана»; 5. Досанова...
Deep vein thrombosis (DVT) is frequently observed in patients with chronic heart failure (CHF), increasing the risk of pulmonary embolism (PE). Clinical evaluation CHF suspected acute PE challenging since these diseases share several symptoms and signs such as dyspnea. Thus, it intuitive that correct fast diagnosis might be able to significantly change their clinical outcome. In present report, we describe a rare case patient due huge deep veins right atrium whom echo permitted therapy.
The coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome (SARS-CoV-2) stimulated the development of highly effective vaccines that were produced with unprecedented speed use new technologies. All newly developed are minimal adverse effects. Clinical introduction AstraZeneca Covid-19 vaccine has raised public alarm regarding rare, but serious thrombotic events, known as vaccine-induced immune thrombocytopenia (VITT). VITT is characterized clinical and laboratory...
Introduction . Venous thromboembolism (VTE) is a major public health issue that frequently underestimated. The primary objective of this multicenter study was to identify patients at risk for VTE, and define the rate receiving appropriate prophylaxis in regions Kazakhstan. Materials methods Standardized case report forms were filled by trained medical doctors on one predefined day selected hospitals. Data analyzed independent biostatistician. Risk VTE categorized according Caprini score...