A5057691168- Oral microbiology and periodontitis research
- Oral Health Pathology and Treatment
- Helicobacter pylori-related gastroenterology studies
- Galectins and Cancer Biology
- GABA and Rice Research
- Streptococcal Infections and Treatments
- HIV/AIDS oral health manifestations
- Probiotics and Fermented Foods
- Carcinogens and Genotoxicity Assessment
- Eosinophilic Esophagitis
- Immune Response and Inflammation
- Algal biology and biofuel production
- Antimicrobial Peptides and Activities
- Curcumin's Biomedical Applications
- Botanical Research and Chemistry
- Enzyme Production and Characterization
- Endodontics and Root Canal Treatments
- Microbial Metabolites in Food Biotechnology
University of Chile
1987-2024
Advanced Center for Chronic Diseases
2022-2024
Universidad Andrés Bello
2023
Centro de Estudios Científicos
2010
Periodontitis, characterized by persistent inflammation in the periodontium, is intricately connected to systemic diseases, including oral cancer. Bacteria, such as Porphyromonas gingivalis and Fusobacterium nucleatum, play a pivotal role periodontitis development because they contribute dysbiosis tissue destruction. Thus, comprehending interplay between these bacteria their impacts on holds significant relevance clinical understanding treatment advancement. In present work, we explored, for...
P. gingivalis has been extensively associated with both the onset and progression of periodontitis. We previously isolated characterized two strains, one from a patient exhibiting severe chronic periodontitis (CP3) another periodontally healthy individual (H3). CP3 strain possessed higher ability forming biofilms invade gingival epithelial cells, compared to H3. Here, we aimed determine whether differences in virulence between these strains could be explained by presence or absence specific...
Porphyromonas gingivalis infection induces apoptosis inhibition in gingival epithelial cells; however, it is not fully understood which bacterial effectors are involved this process. The aim of study to evaluate whether the P. lipopolysaccharide (LPS), specifically O-antigen region, affects adherence, invasion, viability and cells.Gingival cells (OKF6/TERT2 line) were infected by different freshly prepared clinical isolates, obtained from subjects with chronic periodontitis (CP3 CP4) healthy...
Background Porphyromonas gingivalis is part of the subgingival biofilm and a keystone species in development periodontitis. Interactions between P.gingivalis other bacteria biofilms have been shown to affect bacterial virulence. Helicobacter pylori also inhabits biofilm, but consequences interactions there with remain unknown. Here, we investigated how pre-incubation H.pylori affects virulence.Methods We assayed internalization by oral keratinocytes (OKs), hemagglutination formation identify...
The bacterium Helicobacter pylori (H. pylori) represents a major risk factor associated with the development of gastric cancer. anti-oxidant curcumin has been ascribed many benefits to human health, including bactericidal effects. However, these effects are poorly reproducible because molecule is extremely unstable and water insoluble. Here we solubilized as either nanoemulsions or chitosan nanocapsules tested on H. pylori. were average 200 nm in diameter PdI ≤ 0.16 negative zeta potential...
Mutagenesis of Clostridium butyricum ATCC 19398 was best accomplished by u. v. irradiation (254 nm) and methyl methane sulphonate. Nitrosoguanidine only slightly mutagenic for this organism. Procedures are described which yielded a variety auxotrophic antibiotic‐resistant mutant strains.
Mutagenesis of Clostridium butyricum ATCC 19398 was best accomplished by u.v. irradiation (254 nm) and methyl methane sulphonate. Nitrosoguanidine only slightly mutagenic for this organism. Procedures are described which yielded a variety auxotrophic antibiotic‐resistant mutant strains.