A5017865683- Corneal surgery and disorders
- Corneal Surgery and Treatments
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Retinal Diseases and Treatments
- Ophthalmology and Visual Impairment Studies
- Ocular Surface and Contact Lens
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Genetic Associations and Epidemiology
- Musculoskeletal Disorders and Rehabilitation
- Multiple Sclerosis Research Studies
- scientometrics and bibliometrics research
- Retinopathy of Prematurity Studies
- Social Media in Health Education
- Health Literacy and Information Accessibility
- Biomedical Text Mining and Ontologies
- Health Sciences Research and Education
- Assisted Reproductive Technology and Twin Pregnancy
- Ocular Infections and Treatments
- Reproductive Health and Contraception
- Viral Infectious Diseases and Gene Expression in Insects
- Intraoperative Neuromonitoring and Anesthetic Effects
- Leprosy Research and Treatment
- Monoclonal and Polyclonal Antibodies Research
Flinders University
2013-2024
Flinders Medical Centre
2014-2022
Adelaide Institute for Sleep Health
2021
To compare graft survival and visual outcomes for endothelial keratoplasty (EK) after a first penetrating (PK), with of repeat PK PK.400 eyes second (65 EKs, 335 PKs) performed failure primary were identified through the Australian Corneal Graft Registry, national prospectively followed cohort. Grafts January 2008 (follow-up extending to 6.75 years maximum). Kaplan-Meier plots constructed Cox proportional hazards regression was used identify independent risk factors failure. Best-corrected...
Widespread adoption of modern lamellar procedures has altered the pattern practice corneal transplantation. Herein, we describe recent findings from Australian Corneal Graft Registry and place these data into an international context. The total number grafts reported to doubled over past decade. Deep anterior keratoplasty is increasingly used for keratoconus, while endokeratoplasty displaced penetrating Fuchs endothelial dystrophy. survival visual outcomes have shown improvement time. First...
Abstract Background Effective clinical implementation of polygenic risk testing for glaucoma relies on healthcare professionals' attitudes and knowledge the test. Given emerging applications test, it will likely impact a range professionals require competency in scores concepts all those involved patient care. To our knowledge, this is first study to assess views towards glaucoma. Methods An online cross‐sectional questionnaire was distributed via relevant professional organisations...
To objectively evaluate the changes in vision-specific quality of life (QoL) after multidisciplinary low-vision rehabilitation at Royal Society for Blind Low-Vision Clinic.The standard care model Clinic is optical management initial assessment, with subsequent referral to services as required. Participants completed Impact Vision Impairment Questionnaire (IVI) and Veterans Affairs Visual Functioning (VA LV VFQ-48) before 30 days (to assess outcome management) 3 months follow-up...
Glaucoma is the leading cause of irreversible blindness worldwide; however, vision loss resulting from glaucoma generally can be prevented through early identification and timely implementation treatment. Recently, polygenic risk scores (PRSs) have shown promise in stratifying individual prognostication for primary open-angle (POAG) to reduce disease burden. Integrating PRS testing into clinical practice becoming increasingly realistic; little known about attitudes patients toward such...
Objective: To identify eye banking practices that influence corneal graft survival. Design, setting and participants: Prospective cohort study of records 19 254 followed grafts in 15 160 patients, submitted to the Australian Corneal Graft Registry between May 1985 July 2012. Main outcome measures: Influence preservation method (organ culture, moist pot, Optisol, other); death-to-enucleation, death-to-preservation enucleation-to-graft times; transportation by air; era; indication for on...
Purpose: Recent genome-wide association studies reported strong of genetic variation at the CDKN2B/CDKN2B-AS1 locus on 9p21 with normal-tension glaucoma (NTG) in multiple populations. The mechanism by which this causes disease remains to be elucidated. We investigated DNA methylation CpG islands NTG.Methods: conducted a retrospective case–control study 178 NTG cases and 202 unaffected controls from Australia. CDKN2B CDKN2B-AS1 promoter was measured quantitatively using MassCleave assay,...
PurposePredictive genetic testing of relatives known myocilin (MYOC) gene mutation carriers is an appropriate strategy to identify individuals at risk for glaucoma. It likely prevent irreversible blindness in this high-risk group because treatable condition might otherwise be diagnosed late. The Australian and New Zealand Registry Advanced Glaucoma has established protocols glaucoma genes, including MYOC.MethodsThrough the Glaucoma, we investigated experience 40 unaffected who had undergone...
Respondents to the 2008 South Australian Health Omnibus survey (n = 2996) indicated whether, in previous 12 months, they had searched for information on Internet relating emotional issues such as depression, anxiety or relationship problems. Logistic regression was used examine penetration of e-mental health rural and metropolitan areas (region residence), determine if other demographic variables (age group, gender) also impacted likelihood an individual reporting that obtain information....
Abstract Importance Expected outcomes from endokeratoplasty may vary with surgeon experience. Background It was explored whether a learning curve exists for Descemet stripping endothelial keratoplasties (manual or automated) performed in Australia. Design This is prospective cohort study, various clinical settings. Participants There were 2139 recipients of 2615 grafts, registered by 85 surgeons between January 2006 and December 2013. Methods Kaplan–Meier survival analyses Cox proportional...
Purpose: Integrating polygenic risk scores (PRS) into healthcare has the potential to stratify an individual's of glaucoma across a broad population. Glaucoma is most common cause irreversible blindness worldwide, therefore effective screening for endorsed by population highly important. This study assessed attitude unaffected individuals toward PRS testing glaucoma, and sought identify factors associated with interest in testing. Methods: We surveyed 418 including 193 first-degree relative...
Abstract Background To compare graft survival of endothelial keratoplasty (EK) versus penetrating (PK) in patients with iridocorneal (ICE) syndrome and identify ocular features associated survival. Methods Observational, prospective, cohort study. A total 30 806 first grafts performed between 1985 2020 were identified through the Australian Corneal Graft Registry included this observational, prospective 196 eyes underwent a primary corneal for ICE syndrome. Kaplan–Meier plots Chi‐squared...
Abstract Background Patients' understanding of their condition affect the choice treatment. The aim this study is to evaluate patients' and treatment preferences before after an information session on acute optic neuritis. Methods Participants were asked complete a questionnaire consisting 14 questions presented by neuro-ophthalmologist. highlighted options effects based Optic Neuritis Treatment Trial in plain patient language. stressed finding that high dose intravenous steroid therapy...
Pseudoisochromatic plates, such as Ishihara and Hardy-Rand-Rittler (HRR) tests, are designed screening tools to test colour vision defects. The tests often detect congenital red-green blindness their measurement properties for acquired optic neuropathies not known. aim of this study is determine the sensitivity specificity HRR pseudoisochromatic plates in detecting dyschromatopsia patients with unilateral non-arteritic anterior ischaemic neuropathy. Nineteen were tested using affected...
To investigate prevalence and trends in women's authorship of articles ophthalmic review journals over 2 decades.Literature survey.Total number authors, gender first senior (last-named) were identified all full reviews published Prog Retin Eye Res , Surv Ophthalmol, Curr Opin Ophthalmol for the calendar years 1999, 2009, 2019. The authors was assigned manually by multiple methods. subspecialty area each captured keyword text search. Country origin determined from attributions authors.The 841...
1Ophthalmology, Flinders University, Bedford Park/SA/AUSTRALIA, 2Ophthalmology, Park/AUSTRALIA