- Dental Erosion and Treatment
- Dental Health and Care Utilization
- Oral microbiology and periodontitis research
- Dental materials and restorations
- Bone Tissue Engineering Materials
- Dental Anxiety and Anesthesia Techniques
- Bone and Dental Protein Studies
- Endodontics and Root Canal Treatments
- Calcium Carbonate Crystallization and Inhibition
- Engineering Technology and Methodologies
- Ichthyology and Marine Biology
- Paleontology and Evolutionary Biology
- Cancer and biochemical research
- Dental Implant Techniques and Outcomes
- Evolution and Paleontology Studies
- Dental Radiography and Imaging
- Dental Trauma and Treatments
- Diatoms and Algae Research
- Orthodontics and Dentofacial Orthopedics
- Oral and gingival health research
- Crystal Structures and Properties
- Dermatologic Treatments and Research
- Coral and Marine Ecosystems Studies
- Organometallic Compounds Synthesis and Characterization
- Solid-state spectroscopy and crystallography
Dr. August Wolff (Germany)
2017-2025
University of Toronto
2023
University of Duisburg-Essen
2012-2019
Universal Alloy (United States)
2018
Essen University Hospital
2015
Max-Planck-Institut für Nachhaltige Materialien
2014
Max Planck Society
2014
University of Münster
1990
Abstract Caries is a widespread disease in both children and adults. caused by the conversion of fermentable carbohydrates plaque bacteria into acids on tooth surface. Thus, it important to focus sugar reduction control. For efficient removal/control, state-of-the-art toothpastes contain various active ingredients such as antimicrobial agents (e.g., chlorhexidine, stannous salts, zinc salts), abrasives calcium carbonate, phosphates, hydrated silica), surfactants sodium lauryl sulfate methyl...
The aim of this study was to test the dose fluoride toothpaste by parents for their children aged up 24 months.
Background Dental caries is a worldwide challenge for public health. The aim of this 18-month double-blinded, randomized, clinical trial was to compare the caries-preventing effect fluoride-free, hydroxyapatite toothpaste (test) and with sodium fluoride (1450 ppm fluoride; positive control) in adults. Methods primary endpoint percentage subjects showing no increase overall Decayed Missing Filled Surfaces (DMFS) index. study designed as non-inferiority trial. Non-inferiority claimed if upper...
Abstract For caries‐active patients, antimicrobial measures may be useful in addition to mechanical biofilm removal. The aim of this study was investigate the efficacy alternative compounds for use oral care from two main categories (i.e., preservatives and natural compounds) toward biofilms caries‐associated bacteria as compared gold‐standards chlorhexidine digluconate ( CHX ), cetylpyridinium chloride CPC zinc. Compounds were screened initial Streptococcus mutans biofilms. Then, most...
Background: Particulate Hydroxyapatite (HAP; Ca 5 (PO 4 ) 3 (OH)) is being increasingly used as multifunctional active ingredient in oral care. Due to its high similarity human enamel crystallites, it considered a biomimetic agent. Objective: The aim of this narrative review identify the modes action HAP preventive health care based on published studies. outcomes are expected improve understanding effects cavity and provide knowledge base for future research field Methods: data analyzed...
Abstract Background Synthetic particulate hydroxyapatite (HAP; Ca 5 (PO 4 ) 3 (OH)) is used as ingredient in oral care products but its effects on cariogenic biofilms are not clear yet. The primary mode of action HAP may be acting a calcium phosphate reservoir when deposited and release 2+ (hydrogen) ions upon bacterial acid challenge. aim this vitro study was to test hypothesis by investigating potential buffering from challenge planktonic cultures Streptococcus mutans . Methods Planktonic...
Children are prone to develop dental caries. This is supported by epidemiological data confirming early childhood caries (ECC) as a highly prevalent disease affecting more than every second child worldwide. ECC known result from an imbalance between re- and demineralization where dominates due frequent acid production cariogenic bacteria present in oral biofilms. The application of care formulations containing remineralizing agents helps prevent As young children sensitive usually swallow...
In this in vitro study, the influence of concentration abrasive particles on abrasivity toothpastes was investigated using laser scan profilometry polymethyl methacrylate (PMMA) surfaces with aim providing an alternative method to developers for screening new toothpaste formulations. PMMA plates were tested a toothbrush simulator distilled water and four model increasing content hydrated silica (2.5, 5.0, 7.5, 10.0 wt%). The viscosity formulations kept constant by means varying sodium...
Particulate synthetic hydroxyapatite (HAP) is rapidly gaining importance as a biomimetic agent in oral care products. The prerequisite for an adequate effect of the treatment efficient attachment HAP particles to tooth substance. However, quantitative data about interaction and affinity parameters involved are scarce. authors used vitro approach with standardized bovine enamel surfaces aqueous dispersions chemically pure model system. Structural characterization powder using high-resolution...