A5046396766- Retinal and Macular Surgery
- Intraocular Surgery and Lenses
- Retinal Diseases and Treatments
- Retinopathy of Prematurity Studies
- Glaucoma and retinal disorders
- Retinal Development and Disorders
- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Retinal and Optic Conditions
- Vascular Malformations Diagnosis and Treatment
- Ocular Surface and Contact Lens
- Neonatal Respiratory Health Research
- Ocular Infections and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Neonatal and fetal brain pathology
- Retinal Imaging and Analysis
- Corneal Surgery and Treatments
- Neuroscience and Neural Engineering
- Ocular Oncology and Treatments
- Ocular Disorders and Treatments
- Visual perception and processing mechanisms
- Ion channel regulation and function
- Neuroscience and Neuropharmacology Research
- Ophthalmology and Eye Disorders
- melanin and skin pigmentation
Kindai University
2016-2025
Kindai University Hospital
2019-2025
Gazi University
2023
Kindai University Sakai Hospital
2011-2022
Osaka University
2004-2021
University of Occupational and Environmental Health Japan
2021
Ophthalmology Associates (United States)
2000-2021
Alcon (Japan)
2021
Creative Commons
2021
Kyoto Pharmaceutical University
2017
Laser photocoagulation, which is the standard treatment for retinopathy of prematurity (ROP), can have adverse events. Studies anti-vascular endothelial growth factor injections suggested efficacy in ROP, but few studies directly compared them with laser treatments.To compare intravitreal aflibercept vs photocoagulation infants ROP requiring treatment.This noninferiority, phase 3, 24-week, randomized clinical trial was conducted 27 countries (64 hospital sites) throughout Asia, Europe, and...
To report complications in patients after intravitreal injection of bevacizumab to treat ocular diseases associated with vascular endothelial growth factor.We retrospectively reviewed the systemic and that developed within 2 months each 707 (1300 injections) intraocular neovascularization or macular oedema.Nine (1.27%) eight (1.13%) occurred patients. The included corneal abrasion (n = 2), chemosis lens injury 1), inflammation retinal pigment epithelial tear 1) acute vision loss 1). cerebral...
<h3>Aim:</h3> The aim of the study was to evaluate short-term efficacy intravitreal injections bevacizumab for severe retinopathy prematurity (ROP). <h3>Methods:</h3> A retrospective chart review conducted 23 consecutive eyes (stage 3, three eyes; 4A, 18 4B, two eyes) 14 patients with vascularly active ROP considered at high risk progression or development tractional retinal detachment despite conventional laser ablation therapy. Patients received an injection (0.5 mg), either as initial...
<h3>Aim</h3> To evaluate vascularisation of the peripheral retina using fluorescein angiography (FA) digital recordings infants who had been treated with intravitreal bevacizumab (IVB) as sole therapy for zone I and posterior II retinopathy prematurity (ROP). <h3>Methods</h3> A retrospective evaluation was performed medical records, RetCam fundus images angiogram videos 10 neonates (20 eyes) received injections only treatment ROP between August 2007 November 2012. <h3>Results</h3> All eyes...
To validate a vascular severity score as an appropriate output for artificial intelligence (AI) Software Medical Device (SaMD) retinopathy of prematurity (ROP) through comparison with ordinal disease labels stage and plus assigned by the International Classification Retinopathy Prematurity, Third Edition (ICROP3), committee.Validation study AI-based ROP score.A total 34 experts from ICROP3 committee.Two separate datasets 30 fundus photographs each (0-5) (plus, preplus, neither) were labeled...
To assess the efficacy and safety of an intravitreal injection bevacizumab (Avastin(R)) for myopic choroidal neovascularisation (mCNV).Intravitreal (1 mg) was injected into eight eyes patients with mCNV in this non-randomised, interventional case series. The best-corrected visual acuity (BCVA) measured optical coherence tomography (OCT) fluorescein angiography findings were examined before after treatment. minimum follow-up time 3 months.The mean BCVA 0.26 treatment 0.51 at last visit (p =...
Importance Prospective long-term data after retinopathy of prematurity (ROP) treatment with anti–vascular endothelial growth factor injections vs laser therapy are scarce. The FIREFLEYE (Aflibercept for ROP IVT Injection Laser Therapy) next trial is prospectively evaluating the efficacy and safety outcomes following intravitreal aflibercept therapy. Objective To evaluate 2-year ophthalmic 0.4-mg injection or in 24-week randomized (2:1) (FIREFLEYE previously reported). Design, Setting,...
Retinopathy of prematurity (ROP) is a disease that can cause blindness in premature infants. It characterized by immature vascular growth the retinal blood vessels. However, early detection and treatment ROP significantly improve visual acuity high-risk patients. Thus, diagnosis crucial preventing impairment. several patients refrain from owing to lack medical expertise diagnosing disease; this especially problematic considering number cases on rise. To end, we applied transfer learning five...
To determine the clinical characteristics of familial exudative vitreoretinopathy (FEVR) associated with or without pathogenic variants Norrin/β-catenin genes.
Background As gene-specific therapy for inherited retinal dystrophy (IRD) advances, unified variant interpretation across institutes is becoming increasingly important. This study aims to update the genetic findings of 86 retinitis pigmentosa (RP)-related genes in a large number Japanese patients with RP by applying standardised guidelines IRD (J-IRD-VI guidelines) built upon American College Medical Genetics and Genomics Association Molecular Pathology rules, assess contribution these...
Background Gas tamponade with or without vitrectomy is commonly used to treat retinal detachment resulting from a macular hole in highly myopic eye. Redetachment of the retina occurs frequently, however, and pathogenesis redetachment unclear. One possible mechanism leading tangential traction caused by an epiretinal membrane posterior retina. Methods Eleven consecutive eyes were treated vitrectomy, gas silicone oil tamponade, removal membrane. Surgical outcomes clinical characteristics these...