Alejandro Zugasti‐Cruz

ORCID: 0000-0002-8385-6191
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About
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Research Areas
  • Nanoparticle-Based Drug Delivery
  • Venomous Animal Envenomation and Studies
  • Phytochemicals and Antioxidant Activities
  • Pomegranate: compositions and health benefits
  • Receptor Mechanisms and Signaling
  • Nicotinic Acetylcholine Receptors Study
  • Antimicrobial agents and applications
  • Nanocomposite Films for Food Packaging
  • Marine Invertebrate Physiology and Ecology
  • Ion channel regulation and function
  • Characterization and Applications of Magnetic Nanoparticles
  • Bone Tissue Engineering Materials
  • Natural Antidiabetic Agents Studies
  • Traditional and Medicinal Uses of Annonaceae
  • Psidium guajava Extracts and Applications
  • Alkaloids: synthesis and pharmacology
  • Rabies epidemiology and control
  • Iron oxide chemistry and applications
  • Essential Oils and Antimicrobial Activity
  • biodegradable polymer synthesis and properties
  • Plant-derived Lignans Synthesis and Bioactivity
  • Cassava research and cyanide
  • Drug-Induced Hepatotoxicity and Protection
  • Cancer, Hypoxia, and Metabolism
  • Fungal Plant Pathogen Control

Universidad Autónoma de Coahuila
2015-2024

Universidad Nacional Autónoma de México
2001-2013

Gallic acid (GA) is a natural phenolic compound that possesses various biological effects, including antioxidant, anti‑inflammatory, antibiotic, anticancer, antiviral and cardiovascular protection activities. In addition, numerous studies have reported antioxidants possess Hepatitis C virus (HCV) one of the most important causes chronic liver diseases worldwide, but until recently, only small number agents had been developed against HCV. Therefore, present study investigated whether GA...

10.3892/etm.2015.2923 article EN Experimental and Therapeutic Medicine 2015-12-08

The present paper reports the heating ability and hemolysis test of magnetite nanoparticles (MNPs) for biomedical applications, obtained bya novel easy co-precipitation method, in which it is not necessary use controlled atmospheres high stirring rates. Different molarproportions FeCl2:FeCl3 (2:1 3:2 respectively) were used MNPs analyzed by X-ray diffraction, vibrating samplemagnetometry transmission electron microscopy. was evaluated under a magnetic field using solid state induction...

10.1016/j.jart.2016.05.007 article EN Journal of Applied Research and Technology 2016-07-03

Rambutan (Nephelium lappaceum L.) is a tropical fruit from Asia which has become the main target of many studies involving polyphenolic analysis. Mexico produces over 8 million tons per year rambutan, generating huge amount agro-industrial waste since only pulp used and peel, comprises around 45% fruit's weight, left behind. This can later be in recovery fractions. In this work, emerging technologies such as microwave, ultrasound, hybridization both were tested extraction phenolic compounds...

10.3390/molecules27051592 article EN cc-by Molecules 2022-02-28

Abstract BACKGROUND Poly(ethylene terephthalate) (PET) waste films were treated by cold plasma aminolysis to graft primary amino groups (‐NH 2 ) and the surface biocompatibility of polymer was improved. Aminated PET obtained applying radiofrequency (RF) treatment either diethylenetriamine (DTA) or ethylenediamine (EDA). Aminolysis applied during 5, 10 15 min at power levels 150, 175 200 W. RESULTS Water contact angle study revealed that became more hydrophilic after treatment, angles...

10.1002/jctb.7106 article EN Journal of Chemical Technology & Biotechnology 2022-05-09

A large number of magnetic nanomaterials have been studied for their hyperthermic potential, such as iron oxide based materials. These are embedded in different matrices to improve properties. In this paper magnetite was synthesized by the coprecipitation method and an activated carbon/magnetite composite obtained mechanosynthesis (400 rpm, 3 h). The samples were characterized X-ray diffraction (XRD), vibrating sample magnetometer (VSM), IR-FT spectroscopy Scanning Electron Microscopy (SEM)....

10.4236/jbnb.2016.71003 article EN Journal of Biomaterials and Nanobiotechnology 2016-01-01

The Tamaulipan rock rattlesnake (Crotalus lepidus morulus) is a small, cold-tolerant, mountain that occupies the Sierra Madre Oriental in southwestern Tamaulipas, central Nuevo Leon, and southeastern Coahuila Mexico. aim of present study was to analyze compare protein profile proteolytic activity 16 individual four pooled (representative regions Galeana, Santiago, Zaragoza, Tamaulipas) venom samples C. l. morulus from snakes collected northeast Individual venoms were analyzed by SDS-PAGE,...

10.1643/ot-13-005 article EN Copeia 2013-12-30

Abstract A new starch derivative with antibacterial properties and non‐hemolytic effect was synthesized through the chemical grafting of 4‐chloroaniline onto backbone potato starch. In a first step, extracted from potatoes grown in region Coahuila, Mexico, using water steeping method. The hydroxyl groups (C5‐C6) native were oxidized sodium periodate. resulting dialdehyde then chemically modified Schiff base reaction 4‐chloroaniline. structure this confirmed by Fourier transform infrared 1 H...

10.1002/pi.6689 article EN Polymer International 2024-08-05

Diabetic retinopathy (DR) is one of the primary causes blindness in working age population and characterized by angiogenesis retina. Platelets have been suggested to be involved pathogenesis diabetic microvascular complications. The integrin receptor for collagen/laminin, α2β1, mediates platelet adhesion subendothelial tissues, which an essential first step thrombus formation. gene encoding α2 subunit α2β1 has ≥8 polymorphisms, including a BglII/NdeI restriction fragment length polymorphism....

10.3892/etm.2015.2520 article EN Experimental and Therapeutic Medicine 2015-05-26

Zearalenone (ZEA) is a non-steroidal estrogenic mycotoxin produced by variety of Fusarium fungi that are commonly found in feed. ZEA cause reproductive disorders farm animals and occasionally hyperoestrogenic syndromes humans; also, has been shown to be hepatotoxic, genotoxic, hematotoxic immunotoxic, evidence primarily based on studies with different biological models vitro vivo poultry laboratory rodents. However, there little knowledge about the effects human leukocytes. Objective: The...

10.4172/2476-2067.1000102 article EN cc-by Toxicology Open Access 2015-01-01

Abstract: In the sea anemone Bartholomea annulata , four different types of cnidocysts, basitrichous isorhizas, microbasic p‐mastigophores, amastigophores and spirocysts were identified. relation to efficacy substances induce discharge nematocysts we observe that distilled water induced more than 70% p‐mastigophores discharge, whereas discharged in a lesser extent (≈20%). The median lethal dose (LD 50 ) mice was found after injection 700.7 mg protein per kg body weight from crude extract....

10.1111/j.1742-7843.2006.pto_428.x article EN Basic & Clinical Pharmacology & Toxicology 2006-08-01

This work focuses on the obtention of magnetic nanoparticles functionalised with heparin (MNPH) and their interaction Aspergillus niger lipase enzyme. The MNPH were obtained by coprecipitation method, its characterisation was carried out Fourier transform infrared spectroscopy, X‐ray diffraction, alternating gradient magnetometry. Functionalisation ultrasound at various times, later absorption enzyme two temperatures 4 25°C different concentrations lipase. For recovery enzyme, a...

10.1049/mnl.2018.5490 article EN Micro & Nano Letters 2019-02-15
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