Background Breastfeeding is crucial for reducing child mortality but challenges like nipple soreness and improper latching techniques can lead to early cessation. status assessment rely on subjective, Not assessd objectively. Methodology A study of 100 postpartum primipara mothers used an experimental design with non-probability convenient sampling. Participants were divided into two groups:SVD Pfannenstiel incision, each split intervention control subgroups by randomization. The group...

Background: Despite the growing interest in Propolis as an endodontic irrigant, limited research has compared its clinical efficacy and post-operative outcomes with Sodium Hypochlorite (NaOCl), especially concerning pain. The aim of this study was to evaluate compare analgesic properties 5.25% NaOCl 20% Propolis, during initial phase multi visit treatment patients symptomatic irreversible pulpitis (SIP). Methodology: A double blind randomized controlled trial conducted on 44 teeth presenting...

Abstract Introduction: Neuroblastoma is an aggressive childhood cancer originating from neural crest cells, accounting for 700-800 new cases annually and cuases15% of pediatric deaths in the U.S. Treatment high-risk neuroblastoma includes chemotherapy, stem cell transplants, radiation, immunotherapy. Recent evidence suggests that DNMTs inhibitors such as SGI-1027 CM-272 can potentiate apoptosis via epigenetic modulation critical regulatory pathways cancers. Hence, we hypothesized induce...

Background and Objective: Despite a plethora of studies conducted to date, researchers continue investigate the best sealer obturation technique combinations. The aim this study is compare apical seal provided by two bioceramic sealers (Endoseal Endosequence) with that calcium hydroxide (Sealapex), evaluate effect different techniques (cold lateral condensation, continuous wave compaction single cone) on under stereomicroscope. Materials Methods: A total 110 single-rooted mandibular premolar...

Abstract Background Low back pain (LBP) is a common condition contributing to impaired quality of life among professional vehicle drivers. Our study aimed assess LBP prevalence and associated factors bus drivers in Bangladesh. Methods A cross-sectional was conducted 368 using semi-structured questionnaire. Nordic Musculoskeletal Questionnaire (NMQ) subscale used measure LBP. Multivariable logistic regression analysis identify the with Results In last month, 127 (34.51%) participants reported...

Pakistan is the sixth most populous country in World. High rates of consanguinity and inter caste marriages have resulted a substantial burden inherited metabolic disorders (IMDs). Despite this load, there dearth both medical genetic clinical services Pakistan. There are inadequate numbers appropriately trained clinicians, ill-equipped laboratories, lack scientists technologists equipped with skills to deal challenging laboratory investigations involved IMD health care infra-structure unable...

Abstract Background There was a complete lack of information about the treatment outcomes rifampicin/multidrug resistant (RR/MDR) childhood TB patients (age ≤ 14 years) from Pakistan, an MDR-TB 5th high burden country. Therefore, this study evaluated socio-demographic characteristics, drug resistance pattern, and factors associated with unsuccessful among RR/MDR-TB in Pakistan. Methods This multicentre retrospective record review all microbiologically confirmed enrolled for at seven units...

OBJECTIVE:Dental esthetics is a prime consideration for all patients.While restoring teeth, high importance should be given to the size and shape of teeth better esthetic results.Various proportions have been recommended describe relationship between maxillary anterior teeth.Golden Proportion Golden Standard are two ratios most commonly used.The purpose this study was evaluate golden proportion standard in among Pakistani undergraduate students.METHODOLOGY: A cross sectional study, conducted...

Over the past 20 years, shared-mobility services have become important transportation options, as they provide on-demand, door-to-door mobility without requiring vehicle ownership. Although low-income communities may benefit especially from due to their lower ownership and high dependency on public transit, scant research has been conducted exploring how frequently these individuals utilize programmes. This study develops a mathematical model based Zero Inflated Negative Binomial Regression...

There is a paucity of resources focusing on the climate change experience readymade garment (RMG) workers in developing countries such as Bangladesh. Therefore, this mixed method approach aims to understand distinctive types experiences from health and occupational perspective, along with consequences these changes among RMG

Oronasal fistula (ONF) is frequently reported as a complication of cleft palate repair. It not very common after minor oral surgical procedures. A case ONF sequela enucleation an infected palatal radicular cyst with apicoectomy 21, 22, and 23, was referred to the department. whole spectrum procedures starting from small local flaps microvascular tissue transfer, have been employed for closure ONF. This article describes step-by-step procedure using two that provide epithelial covering both...

This study aimed at investigating the reasons of relapse and patterns drug use among substance users in Bangladesh. We have conducted a descriptive type cross-sectional cases substances whole Concerning for after taking treatment; family unrest (29.5%), peer pressure (27.4%), to reduce depression (24.8%) craving drugs (24.3%) were most frequent. Amphetamine was reported be used (76.1%, n = 693), followed by cannabis (75%, 683) alcohol (54.3%, n= 495). Further extensive studies are also...

Intrapulmonary sequestrations are quite uncommon in pediatric age group. The preoperative diagnosis of pulmonary sequestration is not possible most the cases. A 2-year-old boy presented with recurrent episodes chest infections and respiratory distress. congenital lobar emphysema was made on basis radiograph computed tomography scan. At operation, an intralobar found. cyst excised uneventful recovery.

Background: Ischemic heart disease is the interruption of blood supply to causes several biochemical alterations which may lead cardiac dysfunction and ultimately cell death. Medicinal plants plant based foods such as peanut (Arachishypogaea L.) have received great attention for their salutary effects potential treat many aspects ischemic due antioxidant property.Objective: To observe its combination with propranolol in isoproterenol induced myocardial damage rats.Method: This experimental...

Objectives: To document the Outcomes of AV fistula formation for dialysis patients using interrupted sutures.
 Methods: In this Cross-sectional study conducted at PNS Shifa Karachi, from June 2022 to 2023, above 18 years age, male or female, with ESRD/CKD were included. After clinical screening and ultrasound doppler, distal most part wrist was considered as a site radio cephalic AVF. Operation performed under surgical loupe 4.5x magnification. Standard incision about 4-5 cm oblique...