Muhammad Kiwan Akram

ORCID: 0000-0002-8415-9363
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Research Areas
  • Nigella sativa pharmacological applications
  • Pneumonia and Respiratory Infections
  • Patient Satisfaction in Healthcare
  • COVID-19 Clinical Research Studies
  • Antibiotic Use and Resistance
  • SARS-CoV-2 and COVID-19 Research
  • Complementary and Alternative Medicine Studies
  • Heart Failure Treatment and Management
  • Drug-Induced Hepatotoxicity and Protection
  • Dermatological and COVID-19 studies
  • COVID-19 Impact on Reproduction
  • Acute Myocardial Infarction Research
  • Bee Products Chemical Analysis
  • Thyroid Disorders and Treatments
  • Health Systems, Economic Evaluations, Quality of Life
  • Parasites and Host Interactions
  • Parasitic Diseases Research and Treatment
  • Vitamin C and Antioxidants Research
  • Infectious Encephalopathies and Encephalitis
  • Phytochemicals and Medicinal Plants
  • Hematological disorders and diagnostics

University of Veterinary and Animal Sciences
2020-2023

Abstract Until now, no specific and effective treatment exists for coronavirus disease 2019 (COVID‐19). Since honey Nigella sativa (HNS) have established antiviral, antibacterial, antiinflammatory, antioxidant, immunomodulatory properties, we tested their efficacy this in a multicenter, placebo‐controlled, randomized clinical trial at four medical care facilities Pakistan. RT‐PCR confirmed COVID‐19 adults showing moderate or severe were enrolled the trial. Patients randomly assigned 1:1...

10.1002/ptr.7640 article EN Phytotherapy Research 2022-11-24

SUMMARY BACKGROUND No definitive treatment exists for Coronavirus Disease 2019 (COVID-19). Honey and Nigella sativa (HNS) have established antiviral, antibacterial, anti-inflammatory immunomodulatory properties. Hence, we investigated efficacy of HNS against COVID-19. wide METHODS We conducted a multicenter, placebo-controlled, randomized clinical trial at 4 centers in Pakistan. RT-PCR confirmed COVID-19 adults showing moderate or severe disease were enrolled the study. Patients presenting...

10.1101/2020.10.30.20217364 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2020-11-03

Subacute thyroiditis (SAT) is a self-limiting thyroid dysfunction of viral origin. Relatively little known about its occurrence in SARS CoV-2 infected COVID-19 patients. Herein, we report case SAT 58-year-old patient that was apparently triggered by infection with CoV-2. Clinical, laboratory and imaging features the are presented. The vitally stable slightly tender warm gland, which painful on swallowing. His free thyroxine (FT4) elevated, stimulating hormone (TSH) below normal...

10.1016/j.amjms.2021.05.013 article EN other-oa The American Journal of the Medical Sciences 2021-05-21

Abstract Background Coronavirus disease 2019 (COVID-19) caused by the novel coronavirus-infected millions globally. Despite a wide range of advised options for treatment COVID-19, single strategy to tackle this pandemic remains elusive, thus far. That is why we are conducting clinical trial find out efficacy iodine complex clear viral load severe respiratory syndrome coronavirus-2 (SARS-CoV-2) along with reduction in time taken alleviate symptoms. Method The proposed study...

10.1186/s13063-021-05848-8 article EN cc-by Trials 2022-01-19

Abstract Considering that antimicrobial resistance (AMR) is a global challenge, there dire need to gauge the knowledge, attitude, and practice (KAP) of clinicians in endemic countries. The aim current multicenter, cross-sectional study was highlight aptitude gaps (AM) stewardship AMR among practicing doctors working public tertiary care teaching hospitals Lahore, Pakistan. A KAP survey, based on self-administered questionnaire containing 45 questions, conducted 336 6 randomly selected...

10.21203/rs.3.rs-467849/v1 preprint EN cc-by Research Square (Research Square) 2021-05-10

Abstract Objectives Considering the therapeutic potential of honey and Nigella sativa (HNS) in coronavirus disease 2019 (COVID-19) patients, objective study is defined to evaluate prophylactic role HNS. Trial design The a randomized, placebo-controlled, adaptive clinical trial with parallel group design, superiority framework an allocation ratio 1:1 among experimental placebo group. An interim analysis will be done when half patients have been recruited need adapt sample size, efficacy,...

10.21203/rs.3.rs-757643/v1 preprint EN cc-by Research Square (Research Square) 2021-08-09

Abstract Considering that antimicrobial resistance (AMR) is a global challenge, there dire need to gauge the knowledge, attitude, and practice (KAP) of clinicians in endemic countries. The aim current multicenter, cross-sectional study was highlight aptitude gaps (AM) stewardship AMR among practicing doctors working public tertiary care teaching hospitals Lahore, Pakistan. A KAP survey, based on self-administered questionnaire containing 45 questions, conducted 336 6 randomly selected...

10.21203/rs.3.rs-467849/v2 preprint EN cc-by Research Square (Research Square) 2021-07-06
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