Sébastien Schramm

ORCID: 0000-0002-8500-8903
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About
Contact & Profiles
Research Areas
  • Mass Spectrometry Techniques and Applications
  • Analytical chemistry methods development
  • Toxic Organic Pollutants Impact
  • Atmospheric chemistry and aerosols
  • Forensic Fingerprint Detection Methods
  • Petroleum Processing and Analysis
  • Analytical Chemistry and Chromatography
  • Advanced Chemical Sensor Technologies
  • Fermentation and Sensory Analysis
  • Lignin and Wood Chemistry
  • Indoor Air Quality and Microbial Exposure
  • Microbial bioremediation and biosurfactants
  • Botanical Research and Chemistry
  • Ion-surface interactions and analysis
  • Catalysis and Hydrodesulfurization Studies
  • Environmental Chemistry and Analysis
  • Nuclear Physics and Applications
  • Air Quality Monitoring and Forecasting
  • Biosimilars and Bioanalytical Methods
  • HIV/AIDS drug development and treatment
  • Engine and Fuel Emissions
  • Inorganic Fluorides and Related Compounds
  • Fluorine in Organic Chemistry
  • Infectious Encephalopathies and Encephalitis
  • Silicone and Siloxane Chemistry

Université de Lorraine
2014-2024

Université de Versailles Saint-Quentin-en-Yvelines
2017

Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2015-2017

Laboratoire des Sciences du Climat et de l'Environnement
2017

Centre National de la Recherche Scientifique
2017

CEA DAM Île-de-France
2015-2016

Laboratoire d'Étude des Microstructures et de Mécanique des Matériaux
2014

Institut de Chimie et Biochimie Moléculaires et Supramoléculaires
2014

Universidade de São Paulo
2012

Protéomique, Réponse Inflammatoire et Spectrométrie de Masse
2012

Direct Analysis in Real Time (DART™) high-resolution Orbitrap™ mass spectrometry (HRMS) combination with Raman microscopy was used for the detailed molecular level characterization of explosives including not only charge but also complex matrix binders, plasticizers, polymers, and other possible organic additives. A total 15 defused military weapons grenades, mines, rockets, submunitions, mortars were examined. Swabs wipes to collect trace (residual) amounts their constituents from...

10.1007/s00216-016-9691-9 article EN cc-by Analytical and Bioanalytical Chemistry 2016-06-18

Laser desorption ionization Fourier transform ion cyclotron resonance mass spectrometry (LDI-FTICRMS) was used to investigate particulate matter (PM) associated with mainstream (MSS) and sidestream cigarette smokes (SSS). The high resolution the measurement accuracy allowed a molecular formula for each detected signal in 150-500 m/z range be assigned. number of peaks observed spectra required additional data processing extract information. In this context, Kendrick maps Van Krevelen diagrams...

10.1021/ac1019842 article EN Analytical Chemistry 2010-12-02

Detailed molecular composition of solid phase extracted dissolved organic matter (SPEDOM) collected from fractured-rock groundwater was compared to connected surface river water at two different watersheds in the unconfined chalk aquifer Champagne France using full scan ultrahigh resolution electrospray and photoionization Fourier transform ion cyclotron mass spectrometry (FT-ICR MS), Orbitrap tandem MS (MS/MS) 1H magnetic resonance spectroscopy (NMR). NMR indicated that SPEDOM carried a...

10.1016/j.watres.2023.120392 article EN cc-by Water Research 2023-07-20

The objective of this study was to describe an analytical validation a simple, rapid, sensitive, and selective liquid chromatography (LC)-tandem mass spectrometry (MS-MS) method for quantification metronidazole in human plasma samples from bioavailability studies. were pre-treated by liquid.liquid extraction (LLE) with ethyl acetate. Metronidazole the internal standard (IS) zidovudine analyzed combined reversedphase LC-MS-MS positive ion electrospray ionization. Multiple reactions monitoring...

10.1093/chromsci/47.9.781 article EN Journal of Chromatographic Science 2009-10-01

The chemical composition of the particulate phase cigarette smoke inhaled by active smoker is still poorly known in spite its importance from a health point view. A non-targeted approach applied to particles collected on quartz filter obtain an as complete possible description this complex mixture.

10.1002/rcm.8353 article EN Rapid Communications in Mass Spectrometry 2018-11-15

Metronidazole is a BCS (Biopharmaceutics Classification System) class 1 drug, traditionally considered the choice drug in infections treatment caused by protozoa and anaerobic microorganisms. This study aimed to evaluate bioequivalence between 2 different marketed 250 mg metronidazole immediate release tablets. A randomized, open-label, 2×2 crossover was performed healthy Brazilian volunteers under fasting conditions with 7-day washout period. The formulations were administered as single...

10.1055/s-0032-1321873 article EN Arzneimittelforschung 2012-08-23

Aerosols from the mainstream cigarette smoke have been analyzed by electrospray ionization (ESI) coupled to Fourier transform ion cyclotron resonance mass spectrometry (FTICRMS). Measurements conducted in positive mode. The chemical composition of aerosol is significant because it gives insights one complex indoor environmental mixture. Almost 1300 compositions relative nitrogen species were successfully determined through accurate measurement and good production used technique. most...

10.3934/environsci.2015.3.547 article EN cc-by AIMS environmental science 2015-01-01

Nowadays, synthetic polymers are produced and used in many materials for different applications. Matrix-assisted laser desorption/ionization or electrospray mass spectrometry classically to investigate them, but these techniques require sample preparation steps, which not always suitable the study of insoluble formulated polymers. Alternatively, direct real-time (DART) ionization analysis may be conducted without preparation. Four polyvinylidene fluoride (PVDF) involving C2H2F2 repeating...

10.1021/jasms.3c00202 article EN Journal of the American Society for Mass Spectrometry 2023-08-30

This chapter reviews the use of direct analysis in real time-mass spectrometry (DART-MS) context screening (qualitative) and quantitative pollutants environmental contaminants. The contaminants mentioned are mainly derived from chemical industries, agricultural practices, or human personal care products (PCPs), ultimately released into compartments such as surface/underground waters, soils, atmosphere. Pesticides cover a large number substances with varying groups, all sharing common...

10.1002/9783527803705.ch8 preprint EN 2017-12-08

The concentrations of twelve dioxin-like polychlorobiphenyls (DL-PCB) were determined in fifty-seven soils by gas chromatography coupled to tandem mass spectrometry (GC-MS/MS). investigated collected a 72 km2 area close Algiers, the Algerian capital. highest cumulated DL-PCB concentration was 82 µg kg−1. use principal component analysis (PCA) ensured tentative identification contamination sources, which found be associated with release into environment PCB commercial mixtures from electrical...

10.1080/00032719.2020.1743997 article EN Analytical Letters 2020-03-22

Secondary organic aerosols (SOAs) represent a significant portion of total atmospheric aerosols. They are generated by the oxidation volatile compounds (VOCs), and particularly biogenic VOCs (BVOCs). The analysis such samples is usually performed targeted methods that often require time-consuming preparation steps can induce loss and/or sample contaminations.Recently, untargeted using high-resolution mass spectrometry (HRMS) have been successfully employed for broad characterization...

10.1002/rcm.8228 article EN Rapid Communications in Mass Spectrometry 2018-07-04

The iodine transfer polymerization of vinylidene fluoride (or 1,1-difluoroethylene, VDF) controlled by 1-iodoperfluoroalkanes or 1,8-diiodoperfluoroctane led to oligo(VDF)s containing one two end-atom(s). Their deep characterizations utilizing size exclusion chromatography (SEC GPC), 1H and 19F NMR FT-IR spectroscopies, matrix-assisted laser desorption-ionization time-of-flight mass spectrometry (MALDI-TOF) revealed low dispersities, indicating a pseudoliving nature the reaction. In...

10.1021/acs.macromol.4c00926 article EN Macromolecules 2024-08-27

Click to increase image sizeClick decrease size Additional informationNotes on contributorsH. Bergner(Leiter: Prof. Dr. habil. H. Bergner)

10.1080/17450396909419653 article EN Archiv für Tierernaehrung 1969-01-01
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