A5065513933- Receptor Mechanisms and Signaling
- Pain Management and Opioid Use
- Neurological Disorders and Treatments
- Hormonal and reproductive studies
- Exercise and Physiological Responses
- Stroke Rehabilitation and Recovery
- Neuropeptides and Animal Physiology
- Pain Mechanisms and Treatments
- Pharmacological Effects and Assays
- Acute Ischemic Stroke Management
- Opioid Use Disorder Treatment
- Anesthesia and Pain Management
The University of Texas Southwestern Medical Center
2021-2025
Neurological Surgery
2021
The University of Texas at Dallas
2020
Introduction: Over 70% of patients experience post-stroke cognitive impairment (PSCI), which can lead to functional decline. Outpatient stroke clinics often lack a consistent and validated assessment protocol for follow-ups. This increases the risk missed diagnosis PSCI, is determined based on subjective functioning by or caregivers. Our goal was assess practice unstructured PSCI screening at our clinic test if would improve detection in follow-up patients. Methods: We led quality...
Retrospective case control.The purpose of the current study is to determine risk factors associated with chronic opioid use after spine surgery.In our single institution retrospective study, 1,299 patients undergoing elective surgery at a tertiary academic medical center between January 2010 and August 2017 were enrolled into prospectively collected registry. Patients dichotomized based on renewal of, or active prescription 3-mo 12-mo postoperatively. The primary outcome measures for...
ABSTRACT Background There are clinically relevant sex differences in acute and chronic pain mechanisms, but we only beginning to understand their mechanistic basis. Transcriptome analyses of rodent whole dorsal root ganglion (DRG) have revealed differences, mostly immune cells. We examined the transcriptome translatome mouse DRG with goal identifying differences. Methods used Translating Ribosome Affinity Purification (TRAP) sequencing behavioral pharmacology test hypothesis that nociceptor...