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Contact & Profiles
Research Areas
- Venomous Animal Envenomation and Studies
- Biochemical and Structural Characterization
- Toxin Mechanisms and Immunotoxins
Liverpool School of Tropical Medicine
2024
Snakebite envenoming is a major global public health concern for which improved therapies are urgently needed. The antigenic diversity present in snake venom toxins from various species presents considerable challenge to the development of universal antivenom. Here, we used synthetic human antibody library find and develop an that neutralizes long-chain three-finger α-neurotoxins produced by numerous medically relevant snakes. Our bound diverse toxin variants with high affinity, blocked...
10.1126/scitranslmed.adk1867
article
EN
Science Translational Medicine
2024-02-21
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