A5063422411- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Electron and X-Ray Spectroscopy Techniques
- Click Chemistry and Applications
- Advanced Electron Microscopy Techniques and Applications
- Leech Biology and Applications
- Laser-induced spectroscopy and plasma
- Geophysical and Geoelectrical Methods
- Bacteriophages and microbial interactions
- Machine Learning in Materials Science
- Clay minerals and soil interactions
- Geochemistry and Elemental Analysis
- Conducting polymers and applications
- Crystallography and Radiation Phenomena
- Methane Hydrates and Related Phenomena
- Photochromic and Fluorescence Chemistry
- Yersinia bacterium, plague, ectoparasites research
- Salmonella and Campylobacter epidemiology
- Nuclear Receptors and Signaling
- Neuroscience and Neuropharmacology Research
- Calcium Carbonate Crystallization and Inhibition
- nanoparticles nucleation surface interactions
- Venomous Animal Envenomation and Studies
- Escherichia coli research studies
- Enzyme Structure and Function
University of Warsaw
2015-2024
Czech Academy of Sciences, Institute of Physics
2023
Institute of Physics
2023
Dynamical refinement is a well established method for refining crystal structures against 3D electron diffraction (ED) data and its benefits have been discussed in the literature [Palatinus, Petříček & Corrêa, (2015). Acta Cryst. A 71 , 235–244; Palatinus, Corrêa et al. B 740–751]. However, until now, dynamical refinements only conducted using independent atom model (IAM). Recent research has shown that more accurate description can be achieved by applying transferable aspherical (TAAM),...
Parkinson's disease (PD) is a significant health issue because it gradually damages the nervous system. α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors play role in development of PD. The current investigation employed hybrid benzodioxole-propanamide (BDZ-P) compounds to get information on AMPA receptors, analyze their biochemical and biophysical properties, assess neuroprotective effects. Examining characteristics all subunits receptor offers insights into impact BDZ-P...
Campylobacter jejuni is the most frequent cause of human food-borne gastroenteritis and chicken meat main source infection. Recent studies showed that broiler immunization against should be efficient way to lower number infections by this pathogen. Induction mucosal immune system after oral antigen administration provide protective immunity chickens. In work we tested usefulness Lactococcus lactis, extensively studied lactic acid bacterium, as a delivery vector for antigens. First...
In this study, we synthesized benzodioxol carboxamide derivatives and investigated their antidiabetic potential. The compounds (Ia-Ic IIa-IId) underwent characterization via HRMS, 1H-, 13CAPT-NMR, MicroED. Their efficacy against α-amylase was assessed in vitro, while MTS assays were employed to gauge cytotoxicity across cancer normal cell lines. Additionally, the impact of compound IIc evaluated vivo using a streptozotocin-induced diabetic mice model. Notably, IIa displayed potent inhibition...
Reaching beyond the commonly used spherical atomic electron density model allows one to greatly improve accuracy of hydrogen atom structural parameters derived from X-ray data. However, effects asphericity are less explored for diffraction In this work, Hirshfeld refinement (HAR), a method that uses an accurate description by quantum mechanical calculation system interest, was applied first time kinematical This approach here derive structure ordinary hexagonal ice (I
3D electron diffraction (3D ED), or microcrystal (MicroED), has become an alternative technique for determining the high-resolution crystal structures of compounds from sub-micron-sized crystals. Here, we considered L-alanine, α-glycine and urea, which are known to form good-quality crystals, collected ED data on our in-house TEM instrument. In this study, present a comparison independent atom model (IAM) transferable aspherical (TAAM) kinematical refinement against experimental simulated...
Plants are able to produce various types of crystals through metabolic processes, serving functions ranging from herbivore deterrence photosynthetic efficiency. However, the structural analysis these has remained challenging due their small and often imperfect nature, which renders traditional X-ray diffraction techniques unsuitable. This study explores use Microcrystal Electron Diffraction (microED) as a novel method for plant-derived microcrystals, focusing on
Euscorpius is the first research publication completely devoted to scorpions (Arachnida: Scorpiones).Euscorpius takes advantage of rapidly evolving medium quick online publication, at same time maintaining high standards for burgeoning field scorpion science (scorpiology).Euscorpius an expedient and viable serious papers in scorpiology, including (but not limited to): systematics, evolution, ecology, biogeography, general biology scorpions.Review papers, descriptions new taxa, faunistic...