Abstract This study presents a novel fiber‐optic surface‐enhanced Raman spectroscopy (SERS) probe (SERS‐on‐a‐tip) fabricated using simple, two‐step protocol based on off‐the‐shelf components and materials, with high degree of controllability repeatability. Two‐photon polymerization subsequent metallization are adopted to fabricate range SERS arrays both planar substrates end‐facets optical fibers. For the SERS‐on‐a‐tip probes, limit detection 10 −7 m (Rhodamine 6G) analytical enhancement...

When light is incident to a biological tissue surface, combinations of optical processes occur, such as reflection, absorption, elastic and non-elastic scattering, fluorescence. Analysis these interactions with the provides insight into metabolic pathological state tissue. Furthermore, in vivo diagnosis diseases using spectroscopy enables situ rapid clinical decisions without invasive biopsies. For scenarios, can be delivered highly localized manner via fibers, which are placed within...

Background Laparoscopic surgery performed with a patient in the T rendelenburg position is known to have adverse effects on pulmonary gas exchange and respiratory mechanics. We supposed that prolonged inspiratory time can improve at lower airway pressure. Methods One hundred patients undergoing gynaecologic laparoscopic were randomly assigned one of four groups: conventional inspiratory‐to‐expiratory ( I : E ) ratio G roup 1 2), 1), 2 or external positive end‐expiratory pressure PEEP 5 cm H...

The unexpected nuclear accidents have provided a challenge for scientists and engineers to develop sensitive detectors, especially alpha radiation. Due the high linear energy transfer value, sensors designed detect such radiation require placement in close proximity source. Here we report morphological changes optical responses of artificially DNA thin films response exposure as observed by an atomic force microscope, Raman reflectance spectroscopes. In addition, discuss feasibility film...

Background: Epidural anesthesia (EA) is popular for cesarean section, but has some drawbacks such as incomplete block, inadequate muscle relaxation and delayed onset. Combined spinal epidural (CSEA) gained increasing interest it combines the reliability of a block flexibility an block. We investigated efficacy CSEA that main supporting anesthesia, comparing with pH‐adjusted EA, section. Methods: Sixty‐four pregnant women at full term were divided into two groups. Patients in group (n=32)...

There is growing demand for the development of efficient ultrasensitive radiation detectors to monitor doses administered individuals during therapeutic nuclear medicine which often based on radiopharmaceuticals, especially those involving beta emitters. Recently biological materials are used in sensors nanobio disciplines due their abilities detect specific target or sites. Artificially designed two-dimensional (2D) DNA lattices grown a substrate were analyzed after exposure pure emitters,...

We studied the physical characteristics of modified-DNA (M-DNA) double crossover crystals fabricated via substrate-assisted growth with various concentrations four different divalent metallic ions, Cu2+, Ni2+, Zn2+, and Co2+. Atomic force microscopy (AFM) was used to test stability M-DNA metal ion concentrations. The AFM images show that formed without deformation at up critical 6 mM [Cu2+], 1.5 [Ni2+], 1 [Zn2+], [Co2+]. Above these concentrations, exhibited deformed, amorphous structures....

Background: In general, there is a response time between actual arterial hypoxemia and its detection by pulse oximeters. We compared the desaturation resaturation times two types of oximeters, transmission reflectance to find out which oximeter has more rapid time. Methods: Thirty‐three ASA 1 or 2 patients were enrolled in this study. A was placed on index finger forehead monitored simultaneously. After induction general anesthesia without pre‐oxygenation, we waited until oxygen saturation...

Summary We evaluated the effects of three airway manipulation manoeuvres: (a) conventional (single‐handed chin lift); (b) backward, upward and right‐sided pressure ( BURP ) manoeuvre; (c) modified jaw thrust manoeuvre (two‐handed aided by an assistant) on laryngeal view intubation time using Clarus Video System in 215 patients undergoing general anaesthesia with orotracheal intubation. In first part this study, was recorded as a Cormack–Lehane grade each manoeuvre. second part, performed...

We report on a cleaning technique using CO2 clusters for large-scale mono-layer graphene fabricated via chemical vapor deposition (CVD) and its application to reduce contact resistance of the CVD device. found that polymeric residues, i.e., polymethyl methacrylate photoresist which are generated during transfer patterning graphene, can be effectively removed rapid shrinkage, induced by thermal energy low temperature clusters. By applying interface between metal field effect transistor was...

Nano-sized objects interact with biological systems in fundamentally novel ways, thereby holding great promise for targeted drug delivery. It has also been suggested they could constitute a hitherto unseen hazard. Numerous experimental studies the field are taking place. We consider that nature of interactions allows more fundamental theoretical framework to be developed. In particular, we describe intimate link develops between nanoparticle uptake and cell population evolution. Explicit...

Our recent studies on metal–organic nanohybrids based alkylated graphene oxide (GO), reduced (RGO) and InP/ZnS core/shell quantum dots (QDs) are presented. The GO by octadecylamine (ODA) the QD bearing a dodecane thiol (DDT) ligand soluble in toluene. nanocomposite alkylated-GO–QD (GOQD) is readily formed from solution mixture. Treatment of GOQD composite with hydrazine affords reduced-alkylated-GO–QD (RGOQD) composite. structure, morphology, photophysical electrical properties GOQDs RGOQDs...

Summary We evaluated the effects of a prolonged inspiratory time on gas exchange in subjects undergoing one‐lung ventilation for thoracic surgery. One hundred patients were randomly assigned to Group I:E = 1:2 or 1:1. Arterial blood analysis and respiratory mechanics measurements performed 10 min after anaesthesia induction, 30 60 initiation ventilation, 15 restoration conventional two‐lung ventilation. The mean ( SD ) ratio partial pressure arterial oxygen fraction inspired was...

Atrial fibrillation is the most frequent arrhythmia after thoracic surgery and associated with increased hospital costs, morbidity mortality. In this study, we aimed to identify potentially modifiable risk factors for postoperative atrial following lung resection suggest possible measures reduce risk. We retrospectively reviewed medical records of 4731 patients who underwent lobectomy or more major over a 6-year period. Patients developed postoperatively required treatment were included in...

The electronic properties of biomolecules and their hybrids with inorganic materials can be utilized for the fabrication nanoelectronic devices. Here, we report charge transport behavior protein-shelled nanoparticles combined graphene demonstrate possible application as a bionanohybrid capacitor. conductivity PepA, bacterial aminopeptidase used protein shell (PS), platinum (PtNPs) encapsulated by PepA was measured using field effect transistor (FET) graphene-based FET (GFET). Furthermore,...

We introduced reusability process to fabricate the DNA crystals and studied optical band gap of them.

Recent developments in wearable electronics have fueled research into new materials, sensors, and microelectronic technologies for the realization of devices that increased functionality performance. This is further enhanced by advances fabr ication methods printing techniques, stimulating on implantables advancement existing medical devices. article provides an overview designs, embodiments, fabrication methods, instrumentation, informatics as well challenges developing deploying such...

The effectiveness of the Cobra perilaryngeal airway as a routine device and conduit for tracheal intubation has not been prospectively studied to date. This study aimed evaluate its potential role in an emergency rescue, by analysing use bridge blind or fibre-optic-guided intubation.In 49 patients, procedure was carried out follows: fibre-optic view through assessed after insertion airway, then attempted. After evaluating success intubation, performed airway. endotracheal tube removed...

Graphene is a zero band-gap semi-metal with remarkable electromagnetic and mechanical characteristics. This study the first ever attempt to use graphene in surface plasmon resonance (SPR) sensor as replacement material for gold/silver. Graphene, comprised of single atomic layer carbon, purely two-dimensional it an ideal candidate biosensor because its high surface-to-volume ratio. based on occasion wave (SPW) according dielectric constants each metal film detected gas or aqueous phase. SPR...

Abstract We fabricated lanthanide ion (Ln 3+ , e.g. Dy Er Eu and Gd )-doped self-assembled double-crossover (DX) DNA crystals grown on the surface of field effect transistors (FETs) containing either a Cr, Au, or Ni electrode. Here we demonstrate metal electrode dependent FET characteristics as function various Ln . The drain–source current ( I ds ), controlled by voltage V ) -doped DX with Cr an FET, changed significantly under gate voltages g due to relative closeness work energy band gap...

DNA molecules doped with lanthanide and metal ions possess distinct functionalities, providing a feasibility to be utilised in various applications nano- biotechnologies. In the present work, we fabricate thin films seven different (Ce3+, Dy3+, Eu3+, Gd3+, Tb3+, Tm3+, Sm3+) four (Cu2+, Ni2+, Zn2+, Co2+) by drop-casting method. addition, conduct current, Hall transport, optical transmittance, Raman spectroscopic measurements investigate their electrical properties, carrier concentrations...

Metal ion modified DNA synthesized by a substrate-assisted growth method were utilized for VOC gas sensor. Co-DNA lattices with defined periodicity efficiently yield an enhancement in reflected intensities within TLV of methanol vapor selectively.

The feasibility of constructing PNA–DNA hybrid nanostructures by conventional free solution annealing and substrate assisted growth methods was studied.