A5002918200- Venomous Animal Envenomation and Studies
- Amphibian and Reptile Biology
- Rabies epidemiology and control
- Species Distribution and Climate Change
- Wildlife Ecology and Conservation
- Spider Taxonomy and Behavior Studies
- Biochemical and Structural Characterization
- Insect and Pesticide Research
- Antimicrobial Peptides and Activities
- Marine Invertebrate Physiology and Ecology
- Environmental and Biological Research in Conflict Zones
- Toxin Mechanisms and Immunotoxins
- Lepidoptera: Biology and Taxonomy
- Ion channel regulation and function
- Animal Diversity and Health Studies
- Bacillus and Francisella bacterial research
- Nicotinic Acetylcholine Receptors Study
- Insect and Arachnid Ecology and Behavior
- Streptococcal Infections and Treatments
- Entomological Studies and Ecology
- Viral Infections and Vectors
- Monoclonal and Polyclonal Antibodies Research
- Healthcare and Venom Research
- Ecology and Vegetation Dynamics Studies
- Bioactive Natural Diterpenoids Research
Islamic Azad University, Mashhad
2022
Shahid Beheshti University
2018-2020
Qom Islamic Azad University
2018
Islamic Azad University, Tehran
2018
Abstract Protected Areas (PAs) are the cornerstone of biodiversity conservation. Here, we collated distributional data for >14,000 (~70% of) species amphibians and reptiles (herpetofauna) to perform a global assessment conservation effectiveness PAs using distribution models. Our analyses reveal that >91% herpetofauna currently distributed in PAs, this proportion will remain unaltered under future climate change. Indeed, loss species’ ranges be lower inside than outside them....
Broadly-neutralizing monoclonal antibodies are becoming increasingly important tools for treating infectious diseases and animal envenomings. However, designing developing broadly-neutralizing can be cumbersome using traditional low-throughput iterative protein engineering methods. Here, we present a new high-throughput approach the standardized discovery of relying on phage display technology consensus antigens representing average sequences related proteins. We showcase utility this by...
The venom produced by snakes contains complex mixtures of pharmacologically active proteins and peptides which play a crucial role in the pathophysiology snakebite diseases. deep understanding proteomes can help to improve treatment this "neglected tropical disease" (as expressed World Health Organization [WHO]) develop new drugs. most widely used technique for analysis is liquid chromatography/tandem mass spectrometry (LC/MS/MS)-based bottom-up (BU) proteomics. Considering fact that...
Saw-scaled or carpet vipers (genus Echis) are considered to cause a higher global snakebite mortality than any other snake. Echis carinatus sochureki (ECS) is widely distributed snake species, also found across the thirteen provinces of Iran, where it assumed be responsible for most envenomings. Here, we collected Iranian specimens ECS from three different geographically distinct populations, investigated food habits, and performed toxicity assessment venom proteome profiling better...
Envenomation and death resulting from snakebites represent a significant public health problem worldwide, particularly in tropical subtropical regions. The WHO has defined snakebite as neglected concern. Bites Macrovipera lebetina obtusa usually cause life-threatening systemic hemodynamic disturbances, reduced functionality of the kidneys, other serious symptoms, including hypotension shock, edema, tissue necrosis, at bite site. Herein, we highlight five cases M. l. envenomation that...
To date, at least 72 endemic reptilian species have reported from Iran including the Spider-tailed Viper (Pseudocerastes urarachnoides), which has a very limited, narrow distribution, and occurs in areas of western eastern Iraq. The potential distribution Pseudocerastes urarachnoides for present, past (mid- Holocene last glacial maximum), future (2100) was predicted by Maximum Entropy (MaxEnt) modelling using 99 occurrence records as well 19 environmental variables derived climate databases....
Envenoming by Macrovipera lebetina subspecies causes severe life-threatening difficulties for people living in North Africa and the Middle East. To better understand pathophysiology of envenoming improve patient management, knowledge about venom components is essential. Here, proteomes from Cyprus cernovi Iran were characterized using RP-HPLC separation crude proteins, SDS-PAGE fractionated LC-MS/MS peptides obtained in-gel tryptic digestion protein bands. Moreover, we also used...
Scorpion stings are a significant public health concern globally, particularly in tropical and subtropical regions. venoms contain diverse array of bioactive peptides, different scorpion species around the world typically exhibit varying venom profiles, resulting wide range envenomation symptoms. Despite their harmful effects, peptides hold immense potential for drug development due to unique characteristics. Therefore, establishment comprehensive database that catalogs scorpions along with...
Abstract Knowledge gaps regarding species distribution and abundance are great in remote regions with political instability, they might be even larger concerning elusive rare species. We predict the potential for Hierophis andreanus , a poorly known endemic snake Iranian Plateau, assess its conservation status relation to existing protected areas. used maximum entropy modeling tool Mahalanobis distance produce an ensemble model. The most suitable habitats where located mainly mountain ranges...
The updated checklist of amphibians and reptiles Qom Province, Central Iran is presented. Totally 46 species, 35 genera 17 families are reported in the area. most diverse suborder serpentes with 19 species or 41.3% reptile richness region. specious high diversification ranked respectively: Colubridae 11 (23.91%), Agamidae (seven 15.21%), Lacertidae Gekkonidae (each which five 10.86%), Scincidae (four 8.69%), Natricidae Viperidae two 4.3%), Bufonidae, Ranidae, Geoemydidae, Testudinidae,...
Herein, we present three cases of wild Malpolon insignitus preying on Platyceps najadum , Eirenis punctatolineatus and Natrix tessellata from Iran, in addition one observation Kurdistan Iraq. Furthermore, report two new records M. northwestern Iran.
Abstract Broadly-neutralizing monoclonal antibodies are becoming increasingly important tools for treating infectious diseases and animal envenomings. However, designing developing broadly-neutralizing can be cumbersome using traditional low-throughput iterative protein engineering methods. Here, we present a new high-throughput approach the standardized discovery of relying on phage display technology consensus antigens representing an average sequence related proteins. We showcase utility...