A5077682980- Forest Insect Ecology and Management
- Fire effects on ecosystems
- Insect and Pesticide Research
- Forest ecology and management
- Insect-Plant Interactions and Control
- Entomopathogenic Microorganisms in Pest Control
- Forest Ecology and Biodiversity Studies
- Plant and Fungal Interactions Research
- Cancer Treatment and Pharmacology
- Plant and animal studies
- Forest Management and Policy
- Cancer therapeutics and mechanisms
- Entomological Studies and Ecology
- Plant Pathogens and Fungal Diseases
- Pharmacogenetics and Drug Metabolism
- Glioma Diagnosis and Treatment
- Insect behavior and control techniques
- Mitochondrial Function and Pathology
- Genetic Neurodegenerative Diseases
- Nitric Oxide and Endothelin Effects
- Research on scale insects
- Cervical Cancer and HPV Research
- Polyamine Metabolism and Applications
- Testicular diseases and treatments
- Yeasts and Rust Fungi Studies
US Forest Service
2010-2023
University of North Carolina at Chapel Hill
2009
Pacific Southwest Research Station
2004
The University of Texas Health Science Center at San Antonio
2000
Queen's University
2000
3M (United States)
1998
Utah State University
1989-1991
Washington University in St. Louis
1985
Leatherhead Food Research
1981
Substantial genetic variation in development time is known to exist among mountain pine beetle (Dendroctonus ponderosae Hopkins) populations across the western United States. The effect of this on geographic patterns voltinism (generation time) and thermal requirements produce specific pathways have not been investigated. influence fitness traits, body size, sex ratio also unclear. We monitored voltinism, adult ratio, air temperatures at sites latitudinal elevational gradients With exception...
Accurately predicting fire-caused mortality is essential to developing prescribed fire burn plans and post-fire salvage marking guidelines. The model included in the commonly used USA behaviour effects models, First Order Fire Effects Model (FOFEM), BehavePlus, Fuels Extension Forest Vegetation Simulator (FFE-FVS), has not been tested with independently collected tree data. predicts for a wide range of conifer species based on crown scorch species-specific bark thickness. We evaluated 13...
Abstract Background An extreme drought from 2012–2016 and concurrent bark beetle outbreaks in California, USA resulted widespread tree mortality. We followed changes mortality, stand structure, surface canopy fuels over four years after the peak of mortality Sierra mixed conifer pinyon pine ( Pinus monophylla ) forests to examine patterns needle retention death, snag fall across species. then investigated how event affected fuel loading potential impacts on fire hazard emissions. Results...
Cambium injury is an important factor in post-fire tree survival. Measurements that quantify the degree of bark charring on stems after fire are often used as surrogates for direct cambium because they relatively easy to assign and non-destructive. However, char codes based these measurements have been inadequately tested determine how well relate live or dead cambium. Methods assessing through sampling also questioned a potential increasing mortality. In this study we data collected from 11...
High-value trees, such as those located in residential, recreational, or administrative sites, are particularly susceptible to bark beetle (Coleoptera: Curculionidae: Scolytinae) attack a result of increased amounts stress associated with drought, soil compaction, mechanical injury, vandalism. Tree losses these unique environments generally have substantial impact. The value individual cost removal, and loss esthetics may justify protection until the main thrust infestation subsides. This...
PURPOSE: To evaluate the toxicity and pharmacologic behavior of novel mushroom-derived cytotoxin irofulven administered as a 5-minute intravenous (IV) infusion daily for 5 days every 4 weeks to patients with advanced solid malignancies. PATIENTS AND METHODS: In this phase I trial, 46 were treated doses ranging from 1.0 17.69 mg/m 2 IV (two received 1-hour infusion) weeks. The modified continual reassessment method was used dose escalation. Pharmacokinetic studies performed on 1 characterize...
The objective of this study was to test the hypothesis that activation soluble guanylyl cyclase and increased cGMP formation in brain would improve task acquisition cognitively impaired animals. We evaluated effects a novel nitrate ester, GT 715 (2,3-dinitrooxy-(2,3-bis-nitrooxy-propyldisulfanyl)-propane), scopolamine-induced impairment Morris water maze. improved scopolamine-pretreated animals time-and dose-dependent manner, whereas prototypical glyceryl trinitrate (GTN), ineffective. also...
Black-stain root disease is a threat to conifer forests in western North America. The caused by the ophiostomatoid fungus Leptographium wageneri (W.B. Kendr.) M.J. Wingf., which associated with number of bark beetle (Coleoptera: Scolytidae) and weevil species Curculionidae). We developed polymerase chain reaction test identify quantify fungal DNA directly from insects. was detected on 142 384 samples (37%) collected Lassen National Forest, northeastern California, during years 2001 2002....
We performed a Phase I and pharmacokinetic study to determine the maximum tolerated dose of irofulven (6-hydroxymethylacylfulvene; MGI-114, MGI PHARMA, Inc.), administered in intermittent weekly schedules patients with advanced solid tumors.Three were tested: A, days 1, 8, 15 every 4 weeks; B, 1 8 3 C, weeks. Drugs as 5- 30-min (schedules B C) infusions. Dose levels 10, 12, 14 mg/m(2)/week explored.Ninety-nine received 256 cycles. Fifteen 74 evaluable for experienced 16 dose-limiting...
The primary objective of this study was to assess the antitumor activity irofulven in patients with hormone-refractory prostate cancer by measuring a sustained decrease 50% or greater serum prostate-specific antigen (PSA) levels.Forty-two (median age, 73 years) received at least 1 dose 10.6 mg/m2 per day on days 1-5 28-day course. Eligible had pathologically confirmed metastatic adenocarcinoma and not prior cytotoxic chemotherapy.Forty-two median 3 courses irofulven. Thirty-two 2 therapy...
Abstract Wildland fires have a multitude of ecological effects in forests, woodlands, and savannas across the globe. A major focus past research has been on tree mortality from fire, as trees provide vast range biological services. We assembled database individual-tree records prescribed wildfires United States. The Fire Tree Mortality (FTM) includes 164,293 individual with fire injury (crown scorch, bole char, etc.), diameter, either or top-kill up to ten years post-fire. Data span 142...
High-value trees, such as those located in residential, recreational, or administrative sites, are particularly susceptible to bark beetle (Coleoptera: Curculionidae: Scolytinae) attack a result of increased amounts stress associated with drought, soil compaction, mechanical injury, vandalism. Tree losses these unique environments generally have substantial impact. The value individual cost removal, and loss esthetics may justify protection until the main thrust infestation subsides. This...
The red turpentine beetle, Dendroctonus valens (LeConte) (Coleoptera: Scolytidae), is a common bark beetle species found throughout much of North America. Aggregation pheromones have yet to be isolated and identified for D. valens. In this study, we examined the response predator, Temnochila chlorodia (Mannerheim) Trogositidae), host produced kairomones spp. pheromone component exo-brevicomin. A total 11,604 586 T. were captured in multiple-funnel traps over 14-wk period from 27 March 5 July...
Bark beetles (Coleoptera: Curculionidae, Scolytinae) are commonly recognized as important tree mortality agents in coniferous forests of the western U.S.A. High stand density is consistently associated with bark beetle infestations forests, and therefore thinning has long been advocated a preventive measure to alleviate or reduce amount beetle‐caused mortality. The present study aimed determine effectiveness susceptibility over 10‐year period Pinus jeffreyi on Tahoe National Forest,...
Critical research and dialogue are underway to understand the consequences of massive wave tree mortality in Sierra Nevada.
The erythrina gall wasp (EGW), believed native to Africa, is a recently described species and now serious invasive pest of Erythrina (coral trees) in tropical subtropical locales. are favored ornamental landscape trees, as well members threatened ecosystems. EGW tiny, highly mobile, that deforms (galls) host trees causing severe defoliation tree death. first detection the United States was O´ahu, Hawai´i April 2005. It quickly spread through Hawai`ian island chain (U.S.) killing little two...
The effects of cold period duration and simulated rain on adult apple maggot, Rhagoletis pomonella Walsh, emergence were investigated under laboratory conditions. Pupae exposed to periods ranging from 9 191 d. There was no fly pupae ≤23 d cold. degree-day (6.5°C threshold) requirements for first 50% increased 37 65 d; however, flies longer (79–191 d) required fewer heat units emergence. effect (2 cm) tested at various accumulations (677–1,065) during pupal development. any the significantly...
Specimens of an ambrosia beetle, Xyleborus monographus (Fabricius), were found infesting oak trees in California. This is the first record this species established North America. Based on collection information, most likely has been Napa County area for several years. A modified key to America, and diagnosis provided.