- Insect Utilization and Effects
- Environmental Toxicology and Ecotoxicology
- Nanoparticles: synthesis and applications
- Animal and Plant Science Education
- Insect and Arachnid Ecology and Behavior
- Insect and Pesticide Research
- Physiological and biochemical adaptations
- Insect Resistance and Genetics
- Genetically Modified Organisms Research
- Insect Pest Control Strategies
- Molecular Biology Techniques and Applications
- Aquaculture disease management and microbiota
- Environmental Sustainability in Business
- Neurobiology and Insect Physiology Research
- Muscle metabolism and nutrition
- Study of Mite Species
- Heavy metals in environment
- Insect-Plant Interactions and Control
- Fish Ecology and Management Studies
- Agriculture Sustainability and Environmental Impact
- Pesticide and Herbicide Environmental Studies
- Freshwater macroinvertebrate diversity and ecology
- Microplastics and Plastic Pollution
- Pharmaceutical and Antibiotic Environmental Impacts
- Bioeconomy and Sustainability Development
Danish Technological Institute
2017-2022
Aarhus University
2007-2017
University of Reading
2006-2010
Syngenta (United Kingdom)
2008
University of Antwerp
2008
Ibuprofen and other nonsteroidal anti-inflammatory drugs have been designed to interrupt eicosanoid metabolism in mammals, but little is known of how they affect nontarget organisms. Here we report a systems biology study that simultaneously describes the transcriptomic phenotypic stress responses model crustacean Daphnia magna after exposure ibuprofen.Our findings reveal intriguing similarities mode action ibuprofen between vertebrates invertebrates, suggest has targeted impact on...
Abstract Background Normalization of target gene expression, measured by real-time quantitative PCR (qPCR), is a requirement for reducing experimental bias and thereby improving data quality. The currently used normalization approach based on using one or more reference genes. Yet, this extends the work load suffers from assumptions that may be difficult to meet validate. Results We developed driven algorithm (NORMA-Gene). An analysis performance NORMA-Gene compared artificially generated...
Transcriptomic techniques are now being applied in ecotoxicology and toxicology to measure the impact of stressors develop understanding mechanisms toxicity. Microarray technology particular offers potential thousands gene responses simultaneously. However, it is important that microarrays should be validated, at least initially, using real-time quantitative polymerase chain reaction (QPCR). The accurate measurement target expression requires normalisation an invariant internal control e.g.,...
Eicosanoids are biologically active, oxygenated metabolites of three C20 polyunsaturated fatty acids. They act as signalling molecules within the autocrine or paracrine system in both vertebrates and invertebrates mainly functioning important mediators reproduction, immune ion transport. The biosynthesis eicosanoids has been intensively studied mammals it is known that they synthesised from acid, arachidonic through either cyclooxygenase (COX) pathway; lipoxygenase (LOX) cytochrome P450...
Little is known about the potential threats of silver nanoparticles (AgNPs) to ecosystem health, with no detailed report existing on stress and immune responses soil invertebrates. Here we use earthworm primary cells, cross-referencing human cell cultures a particular emphasis conserved biological processes, provide first in vitro analysis molecular cellular toxicity mechanisms Eisenia fetida exposed AgNPs (83 ± 22 nm). While observed clear difference cytotoxicity dissolved salt coelomocytes...
DNA microarrays can be used to measure environmental stress responses. If they are predictive of impact, we need determine if altered gene expression translates into negative impacts on individuals and populations. A large cDNA microarray (14000 spots) was created molecular responses cadmium in Daphnia magna, the most widely aquatic indicator species, relate population growth rate (pgr). We array detect differences transcription genes juvenile D. magna (24 h old) after 24 exposure a control...
Background: Increased amino acid availability stimulates muscle protein synthesis (MPS), which is critical for maintaining or increasing mass when combined with training. Previous research suggests that whey superior to soy in regard stimulating MPS and mass. Nevertheless, respect a future lack of dietary an need using eco-friendly sources it great interest investigate the quality alternative sources, like insect protein. Objective: Our aim was compare postprandial (AA) AA profile blood...
The aim of this study was to evaluate the crude protein quality two mealworm species Alphitobius diaperinus (AD) and Tenebrio molitor (TM) across different processing methods AD using digestibility-corrected amino acid score (PDCAAS) based on rat trials. Rats (66±3 g) were kept in single enclosures fed diets containing 10% protein. eight treatments freeze-dried TM, AD, defatted extruded formic hydrolysed industrial-dried vacuum-dried addition an enzyme blend product (n=6 rats). Total...
A glasshouse experiment was undertaken to provide baseline data on the variation between conventional maize (Zea mays L.) varieties and genetically modified plants expressing insecticidal Bacillus thuringiensis protein (Bt, Cry1Ab). The objective determine whether in soil parameters under a range of cultivars exceeded differences Bt non-Bt cultivars. Variations plant growth (shoot root biomass, percentage carbon, nitrogen), concentration shoots, roots soil, nematode abundance microbial...
Effects of C60 exposure (0, 15 or 154 mg/kg soil) on the earthworm Lumbricus rubellus were assessed at tissue and molecular level, in two experiments. In first experiment, earthworms exposed for four weeks, second lifelong. both experiments, gene expression heat shock protein 70 (HSP70) decreased. For catalase glutathione-S-transferase (GST), no significant trends enzyme activity observed. Gene coelomic cytolytic factor-1 (CCF-1) did not alter but was significantly down-regulated lifelong...
Abstract esticides are constantly beingapplied to agricultural catchments, but little is known abouttheir impact onaquatic biota during natural exposure. In the present study, of pyrethroid lambda‐cyhalothrin was studied in an in‐stream mesocosm setup. Twice summer 2002, macroinvertebrate community exposed situ a 30‐min pulse lambda‐cyhalothrin. Pyrethroid doses were released through modified drip set with nominal concentrations 0.10, 1.00, and 10.0 μg L −1 first exposure 0.05, 0.50, 5.00...
During prolonged resistance training, protein supplementation is known to promote morphological changes; however, no previous training studies have tested the effect of insect isolate in a human trial. The aim this study was investigate potential as dietary supplement increase muscle hypertrophy and strength gains during young men. Eighteen healthy men performed four day/week for eight weeks. Subjects were block randomized into two groups consuming either an or isocaloric carbohydrate within...
An organism is a dynamic system, and its life history results from underlying processes in time. The effects of biological chemical stressors on this system therefore also change temporally. In the present short communication, we emphasize importance including time as factor stress ecology ecotoxicology argue that current standard test protocols may benefit considerably this, improving data interpretation thus risk assessment management.