Junyang Chen

ORCID: 0000-0002-8598-3872
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About
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Research Areas
  • Probiotics and Fermented Foods
  • Gut microbiota and health
  • Gastrointestinal motility and disorders
  • Clostridium difficile and Clostridium perfringens research

Union Hospital
2023-2024

Jilin University
2023-2024

Abstract Geniposidic acid (GPA) is a bioactive compound isolated from Gardenia jasminoides Ellis ( Rubiaceae ) that has long been used to treat arthritis, jaundice, and hypertension. However, the therapeutic effects of GPA against colitis remain underexplored. This study aimed investigate effect on remission underlying mechanisms. A DSS‐induced mouse model was evaluate influence modulation gut microbiota intestinal epithelial barrier function. Our results indicated improved colitis,...

10.1002/ptr.7819 article EN Phytotherapy Research 2023-04-26

Abstract Inflammatory bowel disease (IBD) is a kind of recurrent inflammatory disorder the intestinal tract. The purpose this study was to investigate effects Weissella paramesenteroides NRIC1542 on colitis in mice. A model induced by adding 1.5% DSS sterile distilled water for seven consecutive days. During process, mice were administered different concentrations W. NRIC1542. Colitis assessed DAI, colon length and hematoxylin–eosin staining sections. expressions NF‐κB signaling proteins...

10.1096/fj.202401213r article EN The FASEB Journal 2024-07-04
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