A5023662471- Ultrasound and Hyperthermia Applications
- Photoacoustic and Ultrasonic Imaging
- Bone Tissue Engineering Materials
- Microfluidic and Bio-sensing Technologies
- Ultrasound Imaging and Elastography
- Microbial Inactivation Methods
- Microfluidic and Capillary Electrophoresis Applications
- Dental Implant Techniques and Outcomes
- Ultrasound and Cavitation Phenomena
- Orthopedic Infections and Treatments
- Building Energy and Comfort Optimization
- Advanced MRI Techniques and Applications
- Neonatal Respiratory Health Research
- Orthopaedic implants and arthroplasty
- Fluid Dynamics Simulations and Interactions
- Spacecraft and Cryogenic Technologies
- Heat Transfer and Optimization
- Spectroscopy Techniques in Biomedical and Chemical Research
- RNA Interference and Gene Delivery
- Neonatal and fetal brain pathology
- Laser Applications in Dentistry and Medicine
- Fluid Dynamics and Heat Transfer
- Viral Infections and Outbreaks Research
- Microwave Imaging and Scattering Analysis
- Urban Heat Island Mitigation
The University of Texas Southwestern Medical Center
2019-2024
Southwestern Medical Center
2019-2024
CTL Amedica (United States)
2023
Kookmin University
2016-2019
Boramae Medical Center
2018-2019
Seoul National University
2018-2019
Shamnur Shivashankarappa Institute of Medical Sciences & Research Centre
2013-2017
Abstract Hundreds of thousands human implant procedures require surgical revision each year due to infection. Infections are difficult treat with conventional antibiotics the formation biofilm on surface. We have developed a noninvasive method eliminate metal implants using heat generated by intermittent alternating magnetic fields (iAMF). Here, we demonstrate that and synergistic in elimination. For Pseudomonas aeruginosa biofilm, bacterial burden was reduced >3 log iAMF ciprofloxacin...
Hyperthermia is a potent radiosensitizer, and its effect varies according to the different types of cancer cells. In present study, radiosensitizing hyperthermia on lung cell lines A549 NCI-H1299 was determined based equivalent radiation dose escalation. vitro experiments were conducted using determine thermal radiosensitivity. vivo mouse heterotopic xenograft models treatment response increase in temperature tumors 13.56 MHz radiofrequency (RF) device. Using α β values linear-quadratic...
To evaluate the synergistic effect of radiotherapy and radiofrequency hyperthermia therapy in treatment lung liver cancers, we studied mechanism heat absorption transfer tumor using electro-thermal simulation high-resolution temperature mapping techniques. A realistic tumor-induced mouse anatomy, which was reconstructed segmented from computed tomography images, used to determine thermal distribution tumors during (RF) heating at 13.56 MHz. An RF electrode as a source, computations were...
Traditional moxibustion therapy can stimulate heat and blood-vessel expansion advance blood circulation. In the present study, a novel noncontact-type thermal therapeutic system was developed using near-infrared laser diode. The device allows direct interaction of infrared light with skin, thereby facilitating controlled temperature distribution on skin deep tissues below skin. While tissue-mimicking phantom as substitute for real most important optical parameters are absorption/attenuation...
Abstract Prosthetic joint infection (PJI) is a complication of arthroplasty that results in significant morbidity. The presence biofilm makes treatment difficult, and removal the prosthesis frequently required. We have developed non-invasive approach for eradication from metal implants using intermittent alternating magnetic fields (iAMF) to generate targeted heating at implant surface. goal this study was determine whether iAMF demonstrated efficacy an vivo model. combined with antibiotics...
Buckling or structural instability is a common failure in mechanical, aerospace and civil structures under compressive loads. Any mechanical structure subjected to axial load assumed as column. Therefore, excellent knowledge on buckling behaviour of columns necessary an airframe constructed long slender plates stiffeners, which half will experience leading if overloaded. The present study estimates the compression. Experiments were conducted influence end conditions, length, thickness...
Aim: Treatment of infected orthopedic implants remains a major medical challenge, involving prolonged antibiotic therapy and revision surgery, adding >$1 billion annual burden to the health care system in US alone. Exposure metallic alternating magnetic fields (AMF) generates heat that can provide noninvasive means target biofilm adhered surface. In this study, an AMF with solenoid coil was constructed for targeting metal plate surgically implanted sheep model.Methods: A tissue-mimicking...
Due to the presence of Dean flow in curved ducts, helical channels have drawn attention recently because practical industrial applications. The manipulation fluids through microfluidic devices is widely used many scientific and areas. In present study, numerical simulations were performed on a microchannel predict impact different design parameters that affect flow. Important geometric such as channel cross section, pitch, radius curvature, number turns considered for analysis. study also...
Separation of particles based on different sizes, detection pathogenic bacteria and isolation leukocytes from whole blood are typical applications spiral or helical microchannels. The present study focuses developing a CD4+ T-cell counting device for monitoring HIV/AIDS patients with the aid minichannel used sample cartridge. For experiment, <TEX>$10{\mu}m$</TEX> sized microbeads were visualization fluorescence imaging system. Alignment was investigated in stationary spinning cartridge...
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Background: Ventilator associated pneumonia contributes nearly half of all cases hospital-acquired pneumonia. Drug resistance among ventilator has obligation device withdrawal in order to achieve clinical and microbiological cure. Aim the study was determine relationship between antibiotic Endotracheal tube biofilm pulmonary pathogens ventilator-associated pneumonia.Methods: A descriptive analytical 100 clinically suspected VAP patients done. Patients were divided into group-I Group-II based...
Mobile phones are widely used as portable electronic devices for communication and it is in close contact with the body of health care workers (HCW)3. may serve vectors nosocomial transmission microorganisms2.
Background: The preterm infant brain is most vulnerable to both haemorrhagic and ischemic injury during the late second early third trimesters. This due vascular, cellular, anatomical features of developing tendency infants experience periods physiological instability at a time when they have limited cerebral circulatory auto regulation. CUS useful for recording PVH, PVL, measurement resistive index ventricular dilatation. study was determine magnitude abnormal intracranial findings among...
Background: Wheezing related to respiratory infections is common in infancy and early child hood. In 1-3% of all infants these are severe enough require hospitalization. Most episodes wheezing life viral origin form a heterogeneous group with different outcomes. The objectives this study were assess the efficacy bronchodilators wheeze associated infection comparing nebulized nonspecific adrenergic agonist -1 adrenaline beta-2 specific salbutamol for treatment tract infection.Methods: was...