A5035323891- Public Health and Nutrition
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Health Systems, Economic Evaluations, Quality of Life
- melanin and skin pigmentation
- Science, Research, and Medicine
- Methodologies in Health Research and Practice
- Craniofacial Disorders and Treatments
- Nutrition, Genetics, and Disease
- Global Public Health Policies and Epidemiology
- Genetics and Neurodevelopmental Disorders
- Nail Diseases and Treatments
- Acne and Rosacea Treatments and Effects
- Adipokines, Inflammation, and Metabolic Diseases
- Orthodontics and Dentofacial Orthopedics
- Diverse Scientific Research Studies
- Natural Antidiabetic Agents Studies
- Cleft Lip and Palate Research
- dental development and anomalies
- Liver Disease Diagnosis and Treatment
- Infective Endocarditis Diagnosis and Management
- Pharmacological Effects of Natural Compounds
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- AI in cancer detection
Universitas Swadaya Gunung Jati
2015-2024
University of Indonesia
2022-2023
Mahidol University
2023
Conference Board
2019
The Professional Society of Genetic Counselors in Asia (PSGCA) was recently established as a special interest group the Pacific Human Genetics. Fostering partnerships across globe, PSGCA's vision is to be lead organization that advances and mainstreams genetic counseling profession ensures individuals have access services. Its mission promote quality services region by enhancing practice curricular standards, research continuing education. PSGCA formally launched during Counseling...
Type 2 diabetes mellitus is major health problem worldwide, including in Indonesia. Acarbose, an alpha glucosidase inhibitor, one of oral pharmacologic management commonly used clinical practice with potent side effect long-term use. Flavonoid-and-tannins containing soursop leaf can stimulate insulin secretion and repair beta pancreatic cell dysfunction. This study was aimed to investigate the comparison on antihyperglycemic between ethanol extract (Annona muricata L.) acarbose...
Apert syndrome, Online Mendelian Inheritance in Man number 101200, is a rare genetic condition, with autosomal dominant inheritance, characterized by craniosynostosis, midfacial malformation, and severe symmetrical syndactyly. syndrome associated other systemic malformations, including intellectual disability. At least seven mutations fibroblast growth factor receptor 2 (FGFR2) gene have been found to cause syndrome. Most cases of are caused one the two most frequent located exon 7...
Xeroderma pigmentosum (XP) is a rare autosomal recessive disease characterized by hypersensitivity of the skin to ultraviolet radiation and other carcinogenic agents. This ailment increased photosensitivity, xerosis, early aging, actinic keratosis, erythematous lesions, hyperpigmentation macules. In this serial case report, we presented four cases with XP from two families in Indonesia. Both were referred rural referral health centers, each family has affected siblings. They had freckle-like...
Background: The cause of obesity is an imbalance between the number calories taken and amount burned. Obesity a complex disease. FTO rs9939609 gene polymorphism one genetic factors that contribute to in addition environmental factors. Numerous researches have suggested connection prevalence Aims: purpose this study ascertain how relates adult obesity. Methods: At Biomolecular Genetics Laboratory UGJ Faculty Medicine, analytical observational using case-control design was carried out with 84...
Background: Hypertension is the leading cause of death globally due to its complications, including coronary heart disease and stroke. In 2018, hypertension cases in West Java were second highest among all populations Indonesia. Genetics one unmodifiable risk factors for hypertension. Angiotensin-converting enzyme insertion/deletion (ACE I/D) gene polymorphism could affect ACE production renin-angiotensin-aldosterone system (RAAS), which linked regulation blood pressure. Aims: To analyze I/D...
Background: This study was aimed to investigate the proportion of gastroesophageal reflux (GER) among electronic cigarette (e-cig) smokers and its association with pattern e-cig smoking.Method: cross-sectional underwent community in Cirebon City, Jawa Barat, ranged from March August 2020. Subjects were enrolled through consecutive sampling method. The data collection used survey containing smoking GER. included duration amount smoking. Gastroesophageal consisted GER-related symptoms...
Background: Apert syndrome is characterized by structural abnormalities of skull, face, eyes, hands and feet. This autosomal dominant disorder caused mutations in FGFR2, a gene encoding for fibroblast growth factor receptor protein. Despite its rare frequency general population, several cases have been identified Indonesia.
Hyperuricemia is a condition where plasma uric acid elevated. Prolonged elevated levels increase the risk of gout. Herbal medication an alternative therapy for gout with minimum side effects. Betel (Piper betle) leaves and breadfruit (Artocarpus atilis) contain natural substances that may reduce levels. The study aims to compare effectiveness betel extract in reducing hyperuricemic male white rats using pre-and-post control group experimental research 24 divided into 4 groups. Negative were...
Abstract Introduction Rheumatic heart disease (RHD) is a chronic condition causing damage in cardiac valvular tissues due to acute rheumatic fever (ARF) post Streptococcus pyogenes or Group A β hemolytic (GABHS) infection. The the valve tissue within can lead congestive failure, strokes, endocarditis, and death. However, only 3–6% of post-streptococcal infection individuals develop ARF, suggesting host susceptibility pathogenesis ARF. Polymorphisms methylenetetrahydrofolate reductase (MTHFR)...
Molecular characterization is important prior to clinical management as it can provide additional information for the of patients. This study aims characterize most common mutation and identify genotype-to-phenotype relations in transfusion-dependent thalassemia A total 30 patients were recruited who had never undergone detection. Peripheral blood samples collected analyzed hematological parameters, hemoglobin component, HBA HBB gene analysis. The was IVS1-5 (41.7%) CD26/HbE (23.3%), with...
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Background: Breast cancer is the second largest in world.The gold standard for breast diagnosis and prognosis grade assessment (mitotic, nuclear pleiomorphism, tubular formation), based on tissue histopathology.However, this has limitation that it subjective semi quantitative.A genetic biomarker known as microRNA (miRNA) may regulate human gene expression by targetting mRNA.One of miRNA, i.e. miR-21, able to suppress tumor suppressor mRNA, resulting increased cellular proliferation...
Background: MicroRNA (miRNA) is noncoding-RNA that comprises 18-22 nucleotides. miRNA binds its gene targets in the 3'-untranslated region (3'-UTR), causing direct degradation of mRNA and repressed translation RNA. regulates various biological processes, including cell proliferation, apoptosis, growth, differentiation, metabolism. Various changes have been identified expression different types cancers. This study aimed to describe miR-155 patients with breast cancer tissue Haji Adam Malik...
Insulin resistance is an important aspect of metabolic endocrine disorder, and adiponectin functions as insulin-sensitizer. Changes in levels are associated with alterations insulin sensitivity. results from various variables that contributes to abnormalities signaling, including a decrease levels. Genetics recognized one the key elements influencing levels, investigations showing ADIPOQ SNP can impact sensitivity plasma Therefore, this study aimed examine association between gene...
Background: Intellectual disability (ID) with dysmorphic features can be caused by many genetic disorders, which commonly overlap one another, making specific diagnosis difficult. Methods: Dysmorphology examination of face, limbs, and external genitalia was performed followed dysmorphology analysis POSSUM Face2Gene software. Results: A 15-year-old girl ID, nonspecific muscle weakness, failure-to-thrive identified. She sat at the age 1.5 years walked 7 years. had her menarche 15 years,...