- Neural and Behavioral Psychology Studies
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Dementia and Cognitive Impairment Research
- Neurological Disease Mechanisms and Treatments
- Neuroscience and Music Perception
- Meta-analysis and systematic reviews
- Ginkgo biloba and Cashew Applications
- Functional Brain Connectivity Studies
- Geriatric Care and Nursing Homes
- Endometriosis Research and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Alzheimer's disease research and treatments
- Neurological Disorders and Treatments
- Medicinal Plants and Neuroprotection
- Heart Rate Variability and Autonomic Control
- Acupuncture Treatment Research Studies
- Health Policy Implementation Science
- Dialysis and Renal Disease Management
- Health Sciences Research and Education
- Menstrual Health and Disorders
- Pregnancy-related medical research
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Cancer Risks and Factors
- Visual perception and processing mechanisms
Western Sydney University
2015-2024
University of Wollongong
2013-2024
Translational Research Institute
2018-2024
Camden and Campbelltown Hospitals
2015-2023
Health Net
2023
South Western Sydney Local Health District
2023
Westmead Institute
2019
University of Basel
1990
The impact of the Internet across multiple aspects modern society is clear. However, influence that it may have on our brain structure and functioning remains a central topic investigation. Here we draw recent psychological, psychiatric neuroimaging findings to examine several key hypotheses how be changing cognition. Specifically, explore unique features online world influencing: a) attentional capacities, as constantly evolving stream information encourages divided attention media sources,...
Abstract This study investigated stimulus‐response patterns of temporal principal components analysis (PCA)–derived event‐related potential (ERP) in a classical auditory habituation paradigm with long interstimulus intervals. The skin conductance response (SCR) was included as the “gold standard” model Orienting Reflex. Thirty participants were presented single series 10 identical 60 dB tones, followed by change trial at different frequency. Single‐trial, electrooculography‐corrected ERPs...
Abstract P300 (or P3) is a major positive complex in the human event-related potential, occurring some 300 ms after stimulus onset and long thought to be cortical correlate of Orienting Reflex, our automatic attention-grabbing response novel stimulus. The Novelty P3 was third subcomponent discovered (after P3a P3b) appeared promising its sensitivity novelty, defining characteristic Reflex. But 15 years later it claimed indistinguishable from previously-discovered P3a. This led decline...
This study examined skin conductance responses, the late positive complex of event-related potential, and pupillary dilation responses as autonomic central correlates orienting reflex (OR) in context indifferent significant stimuli. In particular, we aimed to clarify inconsistencies surrounding response an OR index. An auditory dishabituation paradigm was employed, physiological measures were recorded from 24 participants. Response decrement a repeated stimulus, recovery change subsequent...
Abstract This study aimed to evaluate the efficacy and safety of Ganoderma lucidum for treatment hyperglycaemia other cardiovascular risk components metabolic syndrome using a prospective, double-blind, randomised, placebo-controlled trial. Eighty-four participants with type 2 diabetes mellitus were randomised one three intervention groups: , Cordyceps sinensis, or placebo. The dosage was 3 g/day lucidum, without 16 weeks. primary outcome measure blood glucose (glycosylated haemoglobin...
Heightened pain sensitivity, the amount of experienced in response to a noxious event, is known risk factor for development chronic pain. We have previously reported that pain-free, sensorimotor peak alpha frequency (PAF) reliable biomarker sensitivity thermal, prolonged pains lasting tens minutes. To test whether PAF can provide information about occurring over clinically relevant timescales (i.e., weeks), EEG was recorded before and while participants long-lasting model, repeated...
The dual-process theory of habituation attributes dishabituation, an increase in responding to a habituated stimulus after interpolated deviant, sensitisation, change arousal. Our previous investigations into elicitation and the electrodermal Orienting Reflex (OR) showed that dishabituation is independent sensitisation for indifferent stimuli, arguing against theory's explanation. However, this could not be tested significant stimuli study, because was confounded with incomplete resolution...
Abstract Previous research suggests that young adults do not need active and effortful inhibition to successfully complete the auditory equiprobable go/no‐go task, a view was incorporated into Barry De Blasio's sequential processing schema for this task. However, recent evidence in children could be incorrect. The present aims clarify functionality of N2 P3 subcomponents within proposed schema, assessing role To optimize quantification subcomponents, separate temporal PCAs were applied ERP...
Timely diagnosis of dementia has a wide range benefits including reduced hospital emergency department presentations, admissions and inpatient length stay, improved quality life for patients their carers by facilitating access to treatments that reduce symptoms, allow time plan the future. Memory clinics can provide such services, however there is no 'gold standard' model care. This study involved co-creation care new multidisciplinary memory clinic with local community members, General...
Sailuotong (SLT) is a standardised herbal medicine formula consisting of Panax ginseng, Ginkgo biloba, and Crocus sativus, has been designed to enhance cognitive cardiovascular function. Using randomised, double-blind, placebo controlled crossover design, this pilot study assessed the effect treatment for 1 week with SLT (1 washout period) on neurocognitive function in healthy adults. Sixteen adults completed computerised neuropsychological test battery (Compass), had their...
Sailuotong (SLT) is a standardised three-herb formulation consisting of Panax ginseng, Ginkgo biloba, and Crocus sativus designed for the management vascular dementia. While latest clinical trials have demonstrated beneficial effects SLT in dementia, underlying cellular mechanisms not been fully explored. The aim this study was to assess ability act against hydrogen peroxide (H2O2)-induced oxidative damage cultured human endothelial cells (EAhy926). (1–50 µg/mL) significantly suppressed...
Objective: To determine the acceptability and feasibility of acupuncture for treatment endometriosis-related chronic pelvic pain. Design: A prospective, randomized controlled study. Setting: Outpatient setting in Sydney, Australia. Subjects: Participants who were aged 18-45 years, had a confirmed laparoscopic diagnosis endometriosis past 5 regular menstrual periods mean pain scores ≥4/10. Interventions: Sixteen treatments delivered by registered acupuncturists using standardized point...
Abstract Neuropsychological research and practice rely on cognitive task performance measures as indicators of brain functioning. The neural activity underlying stimulus‐response processes can be assessed with ERPs, but the relations between these brain's intrinsic resting state EEG are less understood. This study focused neurocognitive functioning 20 healthy young adults in an equiprobable go/no‐go to map ERP correlates behavioral responses examine contributions task‐related outcomes....