Photodynamic therapy (PDT) has emerged as an important minimally invasive tumor treatment technology. The search for effective photosensitizer to realize selective cancer become one of the major foci in recent developments PDT Controllable singlet-oxygen release based on specific cancer-associated events, another layer selectivity mode, attracted great attention years. Here, first time, we demonstrated that a novel mixed-metal metal–organic framework nanoparticle (MOF NP) can be activated by...

Visible-light-driven photoreduction of CO2 to energy-rich chemicals in the presence H2 O without any sacrifice reagent is significance, but challenging. Herein, Eosin Y-functionalized porous polymers (PEosinY-N, N=1-3), with high surface areas up 610 m2 g-1 , are reported. They exhibit activity for photocatalytic reduction CO gaseous O, photosensitizer or reagent, and under visible-light irradiation. Especially, PEosinY-1 derived from coupling Y 1,4-diethynylbenzene shows best performance...

H2 O2 is a significant chemical widely utilized in the environmental and industrial fields, with growing global demand. Without sacrificial agents, simultaneous photocatalyzed synthesis through oxygen reduction reaction (ORR) water oxidation (WOR) dual channels from seawater green sustainable but still challenging. Herein, two novel thiophene-containing covalent organic frameworks (TD-COF TT-COF) were first constructed served as catalysts for via indirect 2e- ORR direct WOR channels. The...

Shoes play an important role in sports and human daily life. Here, in-shoe sensor pad (ISSP) attached to the vamp lining is based on a triboelectric nanogenerator (TENG) for monitoring real-time stress distribution top side of foot. Each unit this ISSP air-capsule TENG (AC-TENG) consisting activated carbon/polyurethane (AC/PU) microsphere array electrodes. The detection range each AC-TENG reaches 7.27 MPa, which enough pressure change during different sports. This multifunctional can realize...

Abstract Vegetation change can alter surface energy balance and subsequently affect the local climate. This biophysical impact has been well studied for forestation cases, but sign magnitude persistent earth greening remain controversial. Based on long-term remote sensing observations, we quantify unidirectional of vegetation radiometric temperature over 2001–2018. Here, show a global negative response with large spatial seasonal variability. Snow cover, greenness, shortwave radiation are...

Abstract Eye tracking provides valuable insight for analyzing visual attention and underlying thinking progress through the observation of eye movements. Here, a transparent, flexible ultra-persistent electrostatic sensing interface is proposed realizing active (AET) system based on induction effect. Through triple-layer structure combined with dielectric bilayer rough-surface Ag nanowire (Ag NW) electrode layer, inherent capacitance interfacial trapping density has been strongly enhanced,...

The huge amount of degraded NCM (LiNi0.5Co0.2Mn0.3O2) cathode materials from spent lithium-ion batteries is arising as a serious environmental issue well severe waste metal resources, and therefore, direct recycling them toward usable electrode again environmentally economically more attractive in contrast to present metallurgical treatments. In this work, we design robust two-step method for materials, which uses the aluminum impurity attached current collector supplement transition...

With the development of science and technology, human-machine interaction has brought great benefits to society. Here, we design a voice gesture signal translator (VGST), which can translate natural actions into electrical signals realize efficient communication in interface. By spraying silk protein on copper device, VGST achieve improved output wide frequency response 20-2000 Hz with high sensitivity 167 mV/dB, resolution detection reach 0.1 Hz. designing its internal structure, resonant...

The energy conversion efficiency of a triboelectric nanogenerator (TENG) is severely limited by the charge density materials, while drastic and unavoidable decay happens during contact due to insufficient retention capacity positive materials. Here, elaborately synthesized acid-ion-doped pyridine-based polybenzimidazole processing with strong capability demonstrated couple negatively corona-polarized electrets. As illustrated thermal stimulation an ion mass spectrometer, formation acid-ion...

Imine-linked isomeric covalent organic frameworks (COFs) with opposite linkage orientations are not rare, but their structure and photocatalytic property corrections still puzzling, let alone the emerging photosynthetic H2O2 performance. Herein, a pair of COFs (TB-COF TA-COF) reversed imine linkages was fabricated. Compared to TA-COF, TB-COF exhibited larger dipole moments better charge carrier separation efficiency, resulting in superior photosynthesis capability via dominant oxygen...

Photocatalytic oxygen reduction reactions and water oxidation are extremely promising green approaches for massive H

Abstract In recent years, liquid–solid triboelectric nanogenerator (LSTENG) has attracted great attention. However, its low average power density and long charging time limit the practical application of this technique. Here, for first time, a combined with external charge‐pumping method (ECP‐LSTENG) is proposed. Compared to traditional LSTENGs, charge storage capacitor added in ECP‐LSTENG store output charges from pumping generator. Then, extraction formed by spreading shrinking processes...

The first and asymmetric total synthesis of rubriflordilactone A, a bisnortriterpenoid isolated from Schisandra rubriflora, has been accomplished in convergent manner. Two enantioenriched fragments were forged together to give functionalized cis-triene. A 6π-electrocyclization/aromatization sequence assembled the penta-substituted arene, formal vinylogous Mukaiyama aldol reaction introduced butenolide side chain.

Abstract We report the use of nickel catalysts for catalytic transfer hydrogenation hydrazones and other ketimines with formic acid. Strongly donating bisphosphines must be used to support catalysts. As in enzymatic catalysis, attractive weak interactions may important stereochemical control by nickel/binapine catalyst.

Abstract Indolosesquiterpenoids are a growing class of natural products that exhibit wide range biological activities. Here, we report the total syntheses xiamycin A and oridamycins B, indolosesquiterpenoids isolated from Streptomyces . Two parallel strategies were exploited to forge carbazole core: 6π-electrocyclization/aromatization indole C2–H bond activation/Heck annulation. The construction their trans -decalin motifs relied on two diastereochemically complementary radical cyclization...

Abstract A borrowing‐hydrogen reaction between amines and alcohols is an atom‐economic way to prepare alkylamines, ideally with water as the sole byproduct. Herein, nickel catalysts are used for direct N‐alkylation of hydrazides arylamines using racemic alcohols. Moreover, a catalyst ( S )‐binapine was asymmetric benzohydrazide benzylic

Abstract The field of asymmetric (transfer) hydrogenation prochiral olefins has been dominated by noble metal catalysts based on rhodium, ruthenium, and iridium. Herein we report that a simple nickel catalyst is highly active in the transfer using formic acid. Chiral α‐ β‐amino acid derivatives were obtained good to excellent enantioselectivity. key toward success was use strongly donating sterically demanding bisphosphine Binapine.

Abstract An asymmetric reductive amination of ketones using both arylamines and benzhydrazide in the presence nickel catalysts was developed. A one‐pot synthesis tetrahydroquinoxalines also developed starting directly from α‐ketoaldehydes 1,2‐diaminobenzene. Formic acid used as a safe economic surrogate for high‐pressure hydrogen gas. Strongly σ‐donating bis(alkylphosphine)s are crucial ancillary ligands stereoselective hydride insertion decarboxylation formate.

Abstract Taking advantage of a 6π electrocyclization–aromatization strategy, we accomplished the first and asymmetric total synthesis rubriflordilactone B, heptacyclic Schisandraceae bisnortriterpenoid featuring tetrasubstituted arene moiety. The left‐hand fragment was accessed through chiral‐pool‐based route, linked to right‐hand by Sonogashira coupling. cis geometry electrocyclization substrates established hydrogenation or hydrosilylation alkyne. An sequence finally built multisubstituted...

Phosphate is an important anion in both the aquatic environment and biological systems. The search for a selective sensitive phosphate ratiometric fluorescent probe to quantify level water samples body fluids of great significance protection ecological human health. Here, porphyrin-based nano metal–organic framework (NMOF), PCN-224, was successfully exploited as simple but highly single-component with accurate composition measurable structure quantitative determination phosphate, based on...

Simple and accurate monitoring of urinary dopamine (DA) concentration is significant, which helpful for the assessment or exclusion catecholamine-producing tumors, such as pheochromocytoma paraganglioma. Herein, a fluorescence/colorimetry/smartphone triple-mode sensing platform DA determination was constructed using copper ion (Cu2+)-modified hydrazone-linked covalent organic frameworks (Cu-BTA-COF). Cu-BTA-COF with 21.67 wt % content exhibited peroxidase-mimic activity. After adding H2O2...

Conventional approaches to studying fish kinematics pose a great challenge for the real-time monitoring of motion kinematics. Here, multifunctional fish-wearable data snooping platform (FDSP) is demonstrated based on an air sac triboelectric nanogenerator (AS-TENG) with antibacterial coating. The AS-TENG not only can harvest energy from swimming but also serves as self-powered sensory module monitor behavior fish. peak output power generated each swing fishtail reach 0.74 mW, while its...

Enantioselective [3 + 2] annulation of N-heteroarenes with alkynes has been developed via a cobalt-catalyzed dearomative umpolung strategy in the presence chiral ligand and reducing reagent. A variety electron-deficient N-heteroarenes, including quinolines, isoquinolines, quinoxaline, pyridines, internal or terminal are employed this reaction, showing broad substrate scope good functionality tolerance. Annulation electron-rich indoles is also developed. This protocol provides straightforward...