A5029305706- Microbial infections and disease research
- COVID-19 epidemiological studies
- Animal Virus Infections Studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Antibiotic Resistance in Bacteria
- Essential Oils and Antimicrobial Activity
- Animal Disease Management and Epidemiology
- Viral Infections and Vectors
- Bacteriophages and microbial interactions
- Virology and Viral Diseases
- Vector-Borne Animal Diseases
- Bacterial biofilms and quorum sensing
- Aquaculture disease management and microbiota
- COVID-19 and Mental Health
- Vaccine Coverage and Hesitancy
- Herbal Medicine Research Studies
- Agricultural and Food Sciences
- Piperaceae Chemical and Biological Studies
- Hepatitis Viruses Studies and Epidemiology
- COVID-19 Pandemic Impacts
- Vector-borne infectious diseases
- Plant Pathogenic Bacteria Studies
- Mosquito-borne diseases and control
- Diverse Scientific Research Studies
Indian Veterinary Research Institute
2019-2024
Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya
2024
Bihar Agricultural University
2024
Bennett University
2021
ORCID
2020
All India Institute of Medical Sciences Raipur
2009
All India Institute of Medical Sciences
2009
In modern drug discovery, molecular docking analysis is routinely used to understand and predict the interaction between a molecule target protein from microbe. Drugs identified in this way may inhibit entry replication of pathogens host cells. The SARS-CoV-2 associated coronavirus disease, COVID-19, has become most contagious deadly pandemic disease world today. abeyance any specific vaccine or therapeutic against SARS-CoV-2, burgeoning situation urges need for effective drugs treat...
Carvacrol is a herbal antimicrobial agent with in vitro activity against several bacterial pathogens. However, multidrug resistant strains of Pseudomonas aeruginosa are to compounds including carvacrol. Resistance P. carvacrol not well studied. This study was aimed identify the gene(s) associated resistance, thus understand its mechanisms aeruginosa. A drug strain isolated from hospital environment. sensitive mutant generated using transposon mutagenesis. The inactivated gene identified as...
Gallibacterium anatis though known since long as opportunistic pathogen of intensively reared poultry birds has emerged in last few years multiple drug resistance causing heavy mortality outbreaks not only but also other domiciled or domestic birds. Due to its fastidious nature, commensal status and with no pathgnomonic lesions diseased G. infection often remains obscure for diagnosis. Poor understanding epidemiology, virulence factors pathogenesis work on development effective vaccine...
Background and Aim: Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli are gradually increasing worldwide carry a serious public threat. This study aimed to determine the antimicrobial resistance pattern of ESBL-producing E. isolated from fecal samples piglets pig farm workers. Materials Methods: Fecal <3-month-old (n=156) workers (n=21) were processed for isolation in MacConkey agar added with 1 μg/mL cefotaxime. (piglets=124; workers=21) tested ESBL production by combined...
During investigations into an outbreak of respiratory distress in broilers chicks, a small round virus was isolated following inoculation chicken embryos. The isolate, designated 612, identified as enterovirus-like on the basis its size and morphology, resistance to chloroform treatment at pH 3.0, intracytoplasmic replication cell culture. produced partial cytopathic effect chick embryo kidney cultures viral antigens could be detected by immunostaining. preferred culture method for 612 onto...
Since the beginning of New Year 2020, countries around world are stumbling due to coronavirus disease (COVID-19) pandemic. Better approaches diagnostics and medical facilities have helped some recover early. Previous exposures epidemics imparted lessons handle such a pandemic with high level preparedness. The World Health Organization (WHO) national health authorities taking great efforts via efficient impactful interventions contain virus. Diagnostic tests as reverse...
This study analyzed the determinants of morbidity, mortality, and case fatality rate (CFR) ongoing pandemic severe acute respiratory syndrome coronavirus-2 disease 2019 (COVID-19). Data for 210 countries territories available in public domains were relation to mandatory vaccination with Bacille-Calmette-Guerin (BCG), population density, median age country population, health care expenditure per capita, life expectancy at birth, healthy expectancy, literacy rate, capita gross domestic...
Antibiotic resistance emergence in bacterial pathogens is a global issue and to control it, government enforce strict drug usage regulations researchers trying search new antibiotics explore the paradigm of combinational therapy with other antimicrobials herbal drugs. Trans-cinnamaldehyde (TC) main component cinnamon oil, which has antimicrobial properties used as medicine. The present investigation was carried out interaction TC few last resort antibiotic drugs for its synergistic...
Ultrasonographic examination, owing to its wide array of functionality, has been proved play an important role in clinical diagnostics. In a rapid evolving scientific arena where laboratory diagnostics clearly have major avert any sort maternal health complications due fetus that may be the abnormal fetal development or mummified fetus, ultrasound edge over others. It accuracy, precision, simpler techniques, handiness and portable nature. documentation normal physiology as well determining...
Neuraminidase (NA) is a viral glycoprotein present in the surface of viruses belonging to paramyxoviridae and orthomyxoviridae. It helps attachment movement airways. also essential for release progeny from infected cells. Thus, anti-neuraminic agents have potential obstruct infection well before virus interacts with host. In study, we describe label-free electrochemical impedance spectroscopy characterise NA inhibitors plant origin against Peste des petits ruminants NA. A decrease charge...
Vaccination of cattle and buffaloes with Brucella abortus strain 19 has been the mainstay for control bovine brucellosis. However, vaccination S19 suffers major drawbacks in terms its safety interference serodiagnosis clinical infection. S19∆per, a perosamine synthetase wbkB gene deletion mutant, overcomes vaccine strain. The present study aimed to evaluate potential S19Δper candidate natural host, buffaloes. Safety animals use, was assessed guinea pigs. Protective efficacy by immunizing...
Gallibacterium anatis biovars have emerged as important poultry pathogens all over the world. However, it has rarely been reported earlier in India. Here we report eight outbreaks of disease “Gallibacteriosis” layers, broilers, pigeons and ducks associated with significantly high mortality birds. The was clinically characterised by pyrexia 41°C to 42°C, watery nasolacrimal discharge diarrheic faces. A total 28 isolates Avibacterium were identified but only G. showed consistent association...
A microcapillary-based loop-mediated isothermal amplification (µcLAMP) has been described for specific detection of infectious reproductive pathogens in semen samples cattle without sophisticated instrumentation. Brucella abortus, Leptospira interrogans serovar Pomona and bovine herpesvirus 1 (BoHV-1) cultures were mixed samples. The µcLAMP assay is portable, user-friendly, cost-effective, suitable to be performed as a POC diagnostic test. We have demonstrated high sensitivity specificity...
An epidemiological study was done to leptospirosis in domestic animals. Sera samples collected from various farm animals (cattle- 331, goat-88, horses -9, dogs -10) parts of the country were examined by Microscopic agglutination test. A panel 12 reference strains used study. Out 438 samples, 27 showed for Leptospira antigens yielding an overall positivity 6.16%. Study revealed that 6.34% cattle and 5.68% goat sera positive leptospiral antibodies. Javanica, hebdomadis grippotyphosa common...
Here, we report the genome sequence of a Pasteurella multocida strain isolated from heart blood spotted deer (Bareilly, India). The 2.44-Mbp has 2,227 coding sequences, with G+C content 40.7%.