A5064691108- Energetic Materials and Combustion
- High-Velocity Impact and Material Behavior
- Supercapacitor Materials and Fabrication
- Hemoglobin structure and function
- Advancements in Battery Materials
- Fluid Dynamics Simulations and Interactions
- Nanoporous metals and alloys
- Additive Manufacturing and 3D Printing Technologies
- Polymer crystallization and properties
- Lipid Membrane Structure and Behavior
- Silicone and Siloxane Chemistry
- Advanced Battery Materials and Technologies
- Electrocatalysts for Energy Conversion
- Numerical methods in engineering
- Graphene and Nanomaterials Applications
- Nanoparticle-Based Drug Delivery
- Computational Fluid Dynamics and Aerodynamics
- Anodic Oxide Films and Nanostructures
- Injection Molding Process and Properties
- Semiconductor materials and devices
- Gas Dynamics and Kinetic Theory
- Ultrasound and Hyperthermia Applications
- Connexins and lens biology
- Graphene research and applications
- High-pressure geophysics and materials
China Academy of Engineering Physics
2023-2024
Chinese Academy of Engineering
2023-2024
University of Nevada, Reno
2018-2020
Our purpose is to design excellent binder candidates used in polymer-bonded explosives (PBX) according the calculated shock of Hugoniot. Here, we mainly examined thermoplastic elastomer (TPE) binders commonly PBX formulations. Equilibrium molecular dynamics (MD) simulation and mixing rule methods were calculate Hugoniot values 180 newly designed TPEs. We focused on influence polymerization degree, contents, types soft hard segments composed TPEs compared them with classic binder, Estane. The...
Bubble-enhanced shock waves induce the transient opening of blood-brain barrier (BBB) providing unique advantages for targeted drug delivery brain tumor therapy, but little is known about molecular details this process. Based on our BBB model including 28 000 lipids and 280 tight junction proteins coarse-grained dynamics simulations, we provided molecular-level mechanism three typical drugs first time, lipophilic paclitaxel, hydrophilic gemcitabine, siRNA encapsulated in liposome, across...
Shock-assisted paclitaxel (PTX) transport across the blood-brain barrier offers a promising treatment strategy for brain tumors. Here, based on realistically complex human plasma membrane (PM) model, we investigated dynamic transmembrane behavior of PTX cluster by shock induced bubble collapse, focusing effect impulse (I), diameter (D) and arrays. The results show that all three factors can control depth (ΔDPM) PTX. For fixed D, ΔDPM grows exponentially with I, ∼ exp eventually reaches...
The crack behaviors under complex stress states are very important for the safety of polymer-bonded explosives (PBXs) accidental stimulations, but their accurate description is a challenge. Due to advances tracking discontinuities and multi-fields coupling, phase-field model fracture phenomena attracting significant interest recently. Conventional models tension-compression symmetric or based on volumetric-deviatoric strain energy split, these conventional may lead unrealistic patterns,...
Abstract Microstructural features such as voids, microcracks and interfaces play an important role in the mechanical properties of polymer‐bonded explosives, which significantly decide performance, safety reliability. A series micron‐scale 3D models were constructed, a cohesive finite element method commercial software was used to study elastic fracture development HMX/Estane explosives under quasi‐static tension. The predicted Young's modulus PBX with particle volume fraction 92.7 % at 0.01...