- Atrial Fibrillation Management and Outcomes
- Hormonal and reproductive studies
- Cardiovascular Health and Disease Prevention
- Sexual function and dysfunction studies
- Cardiac Arrhythmias and Treatments
- Cardiovascular Disease and Adiposity
- Pharmacology and Obesity Treatment
- Heart Rate Variability and Autonomic Control
- ECG Monitoring and Analysis
- Fatty Acid Research and Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diet, Metabolism, and Disease
- Cardiovascular Function and Risk Factors
- Antiplatelet Therapy and Cardiovascular Diseases
- Heart Failure Treatment and Management
- Non-Invasive Vital Sign Monitoring
- Erythropoietin and Anemia Treatment
- Nutritional Studies and Diet
- Liver Disease Diagnosis and Treatment
- Blood Pressure and Hypertension Studies
- Nuts composition and effects
- HIV-related health complications and treatments
- Iron Metabolism and Disorders
- Antioxidant Activity and Oxidative Stress
- Cardiac electrophysiology and arrhythmias
University College Hospital at Westmoreland Street
2023
University College London
2023
Tampere University Hospital
2023
Kuopio University Hospital
2011-2021
Kanta-Hämeen Keskussairaala
2010-2018
University of Eastern Finland
2017
Erectile dysfunction (ED), impaired arterial elasticity, elevated resting heart rate as well increased levels of oxidized LDL and fibrinogen associate with future cardiovascular events. Physical activity is crucial in the prevention diseases (CVD), while metabolic syndrome (MetS) comprises an risk for CVD The aim this study was to assess whether markers subclinical atherosclerosis are associated presence ED MetS, physical protective ED. 57 MetS (51.3 ± 8.0 years) 48 physically active (PhA)...
Background: Pharmacological cardioversion of atrial fibrillation is a reasonable alternative for electrical in acute fibrillation. We compared the efficacy and safety intravenous vernakalant flecainide patients with recent-onset (< 48 h) Methods: A total 200 consecutive patients, 100 undergoing flecainide, were included this single centre non-randomized retrospective study. The primary endpoint was conversion to sinus rhythm within 120 minutes from drug administration. Results:...
All-cause mortality and cardiovascular disease are increased in subjects with metabolic syndrome (MetS). Risk scores used to predict individual risk of heart disease. We performed a long-term follow-up study investigate whether factors such as arterial stiffness, high-sensitive C-reactive protein (hs-CRP) oxidized LDL (OxLDL) can be events Finnish men MetS.
Atrial fibrillation (AF) is the major cause of stroke since approximately 25% all strokes are cardioembolic-origin. The detection and diagnosis AF often challenging due to asymptomatic intermittent nature AF.
Atrial fibrillation is often asymptomatic and intermittent making its detection challenging. A photoplethysmography (PPG) provides a promising option for atrial detection. However, the shapes of pulse waves vary in decreasing accuracy. This study evaluated ten robust features fibrillation. The was national multi-center clinical Finland data were combined from two broader research projects (NCT03721601, URL: https://clinicaltrials.gov/ct2/show/NCT03721601 NCT03753139,...
Accumulation of oxidized low-density lipoproteins in the intimae arteries and endothelial dysfunction are key events development atherosclerosis. Patients with metabolic syndrome at high risk for cardiovascular diseases but linkage between atherosclerosis is incompletely understood. We studied whether levels LDL arterial elasticity differ patients physically active controls. 40 men controls participated this cross-sectional study. None study subjects had been diagnosed disease. Levels were...
Rapeseed oil is the principal dietary source of monounsaturated and n-3 polyunsaturated fatty acids in Northern Europe. However, effect rapeseed on markers subclinical atherosclerosis not known. The purpose this study was to compare effects intake cold-pressed turnip (CPTRO) butter serum lipids, oxidized LDL arterial elasticity men with metabolic syndrome.Thirty-seven syndrome completed an open balanced crossover study. Treatment periods lasted for 6 8 weeks they were separated from each...
Background: Erectile dysfunction (ED) is believed to be an early sign of systemic cardiovascular disease (CVD). Elevated levels circulating oxidised LDL (oxLDL) and impairment arterial elasticity have been reported predict future events. We studied whether metabolic syndrome subjects with without erectile differ in oxLDL elasticity. Furthermore, we assessed the presence ED acts as a clinical marker underlying atherosclerotic process. Methods: Seventy men syndrome, aged 35–60 years, completed...
Objectives. New onset postoperative atrial fibrillation (POAF) after cardiac surgery is associated with increased risk for thromboembolic complications. Compliance anticoagulation treatment prerequisite successful outcome POAF. We hypothesized that a disciplined protocol initiated instantly POAF secures long-term outcome. Design. A total of 519 consecutive patients undergoing were retrospectively analyzed. Patients received using warfarin whenever lasted longer than five min. Postoperative...
SCORE and FINRISK models are designed to estimate patient's risk for cardiovascular diseases (CVD). Increased circulating oxidized LDL (oxLDL) impaired arterial elasticity, on their part, considered as markers of subclinical atherosclerosis. Subjects with metabolic syndrome (MetS) thought be at high CVD because abnormalities.To study among men MetS whether subjects three, four, or five variables different estimated 10-year differ in oxLDL elasticity.OxLDL was assessed by a capture ELISA...
Introduction: Obesity and an inactive lifestyle increase risk for metabolic syndrome cardiovascular disease. We did a cross-sectional study on 120 men with 80 without to investigate the connection between patient-reported physical activity factors. Methods: The subjects' daily amount of exercise was assessed structured questionnaire regarding normal weekly amount, type mode activity. subjects were stratified into different groups their status. compared lipid levels, resting heart rate,...
Introduction: Novel postoperative atrial fibrillation (AF) is a significant problem after cardiac surgery. However, the impact of AF on late morbidity and mortality unclear. The aim our study was to assess predictive value for incidence death, stroke, myocardial infarction (MI) AF. Material methods: Total 519 consecutive cardio surgical patients without prior were retrospectively analysed. All had previously participated in prospective trials concerning prevention between 2004-2008, similar...
Background The aim of this study was to compare acute effects turnip rapeseed oil rich with mono- and polyunsaturated fatty acids cream on postprandial triglyceride levels post-glucose load measures insulin sensitivity in population men metabolic syndrome. Methods This open-label balanced crossover included 37 They underwent an oral glucose-fat tolerance test where they ingested 75 g glucose either 240 mL or 84 depending the arm. Hourly blood samples were drawn up 5 h after determine changes...
Abstract Funding Acknowledgements Goverment grant, Heart2save Ltd cooperation. Background/Introduction: Atrial fibrillation (AF) is the most common arrhythmia and a fast-growing public health problem worldwide. Main severe complication of AF an embolic stroke. Approximately 25% all strokes are caused by AF. often symptomless intermittent, making its detection diagnosing challenging. Many patients have both symptomatic asymptomatic periods arrhythmia. In addition, during early stage disease,...