A5037279100- Radiopharmaceutical Chemistry and Applications
- Medical Imaging and Pathology Studies
- Muon and positron interactions and applications
- Radioactive contamination and transfer
- Medical Imaging Techniques and Applications
- Nuclear Physics and Applications
- Nuclear physics research studies
- Lung Cancer Treatments and Mutations
- Particle accelerators and beam dynamics
- Nuclear reactor physics and engineering
- Radioactivity and Radon Measurements
- Nuclear and radioactivity studies
- Sarcoma Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Soil erosion and sediment transport
- Peptidase Inhibition and Analysis
- RNA modifications and cancer
- Chemical Synthesis and Characterization
- Radioactive element chemistry and processing
University of Bern
2013-2017
Paul Scherrer Institute
2012-2016
Leibniz University Hannover
2010-2015
In recent years, <sup>47</sup>Sc has attracted attention because of its favorable decay characteristics (half-life, 3.35 d; average energy, 162 keV; Eγ, 159 keV) for therapeutic application and SPECT imaging. The aim the present study was to investigate suitability radionuclide therapy in a preclinical setting. For this purpose novel DOTA-folate conjugate (cm10) with an albumin-binding entity used. <b>Methods:</b><sup>47</sup>Sc produced via <sup>46</sup>Ca(n,γ)<sup>47</sup>Ca<math...
In recent years, implementation of <sup>68</sup>Ga-radiometalated peptides for PET imaging cancer has attracted the attention clinicians. Herein, we propose use <sup>44</sup>Sc (half-life = 3.97 h, average β<sup>+</sup> energy [Eβ<sup>+</sup><sub>av</sub>] 632 keV) as a valuable alternative to <sup>68</sup>Ga 68 min, Eβ<sup>+</sup><sub>av</sub> 830 and dosimetry before <sup>177</sup>Lu-based radionuclide therapy. The aim study was preclinical evaluation folate conjugate labeled with...
Exploration of the physics involved in production cosmogenic radionuclides requires experiments using same rare, radioactive nuclei sufficient quantities. For this work, such exotic have been extracted from previously proton-irradiated stainless steel samples wet chemistry separation techniques. The irradiated construction material has arisen an extended research programme at Paul Scherrer Institute, called STIP (SINQ Target Irradiation Program), where several thousand different materials...