- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Endometrial and Cervical Cancer Treatments
- Pelvic floor disorders treatments
- Ovarian cancer diagnosis and treatment
- Lymphatic System and Diseases
- Cancer Risks and Factors
- Ultrasound Imaging and Elastography
- Intraperitoneal and Appendiceal Malignancies
- Clinical Nutrition and Gastroenterology
- Cancer and Skin Lesions
- MRI in cancer diagnosis
- Body Contouring and Surgery
- Endometriosis Research and Treatment
- Pelvic and Acetabular Injuries
- Nutrition and Health in Aging
- Pediatric Hepatobiliary Diseases and Treatments
- Hernia repair and management
- Esophageal and GI Pathology
- Photoacoustic and Ultrasonic Imaging
- Systemic Sclerosis and Related Diseases
- Ovarian function and disorders
- Inflammatory Biomarkers in Disease Prognosis
- Global Cancer Incidence and Screening
- Anorectal Disease Treatments and Outcomes
Hospital de Clínicas da Unicamp
2012-2024
Universidade Estadual de Campinas (UNICAMP)
2015-2024
Hospital de Câncer de Barretos
2023
Universidade Estadual Paulista (Unesp)
2023
Hospital Universitário Onofre Lopes
2013
To evaluate the performance of International Ovarian Tumor Analysis (IOTA) ADNEX model in preoperative discrimination between benign ovarian (including tubal and para-ovarian) tumors, borderline tumors (BOT), Stage I cancer (OC), II-IV OC metastasis a gynecological oncology center Brazil.This was diagnostic accuracy study including 131 women with an adnexal mass invited to participate February 2014 November 2015. Before surgery, pelvic ultrasound examination performed serum levels tumor...
To evaluate the capacity to predict malignancy in women with adnexal tumors using CA 125 measurement and ultrasound criteria.This was a cross-sectional study including 103 total of 110 tumors. level measured sample peripheral blood. Lesions were classified by ultrasound, standardized predetermined criteria, as benign (B) or malignant (M). Those that could not be these criteria assessed subjectively. Histopathologic examination surgical specimens used gold standard.Of tumors, 79 (71.8%) 31...
To assess the performance of Ovarian-Adnexal Reporting and Data System Magnetic Resonance Imaging (O-RADS MRI) score in evaluation adnexal masses to provide technical notes about its current MRI parameters concepts.This was a prospective study 226 patients with 287 (190 submitted surgery or biopsy 97 followed for at least one year). We calculated sensitivity, specificity, positive predictive value, negative value O-RADS score, using ≥ 4 as cutoff malignancy. performed analysis main updates...
Introduction: Polycystic ovary syndrome (PCOS) has been associated with an autoimmune origin, either per se or favoring the onset of diseases, from a stimulatory action on inflammatory response. Thus, thyroiditis (AIT) could be more prevalent among women PCOS.Objective: To evaluate prevalence AIT in PCOS.Study design: It was cross-sectional study, tertiary center, including 65 PCOS and without this condition. Clinical laboratory parameters were evaluated thyroid ultrasound scan performed....
Objectives We examined the performance of 4 risk malignancy index (RMI) variants in a medium‐resource gynecologic cancer center. Methods A total 158 women referred for adnexal masses were evaluated before surgery by RMI variants. Physicians with varied experience ultrasound assessment performed examinations. compared using receiver operating characteristic curve analyses followed calculation sensitivity, specificity, and positive negative likelihood ratios pathologic diagnosis as reference...
Peritoneal ascites are a distinguishable feature of patients with advanced epithelial ovarian cancer (EOC). The presence different lymphocyte subsets has been reported in EOC-associated ascites, which also can or not contain malignant cells. goal this study was to analyze the functional characteristics natural killer (NK) cells from terms their expression activating receptors and ascites’ contents subtypes, cytokine profile EOC NK cell function evaluated by degranulation marker CD107a...
Dermatofibromas are benign skin lesions that consist of pigmented papules or nodules. They produce the dimple sign when laterally squeezed and usually found on legs. These clinical features lead to diagnosis in most cases. However, differential with other lesions, such as atypical nevi melanoma can be difficult, dermoscopy may help diagnosis. There several dermoscopic patterns associated dermatofibromas, common being a central white scar like patch delicate pigment network at periphery. This...
Herein it was evaluated the impact of PD-L1 immunohistochemical expression and stromal tumor-infiltrating lymphocyte (sTIL) counts in pretreatment needle core biopsy on response to neoadjuvant chemotherapy (NACT) for patients with breast carcinomas (BC). In 127 paired pre- post-NACT BC specimens, stroma neoplastic cells. same samples sTILs were semi-quantified tumor stroma. Post-NACT specimens histologically rated as having residual cancer burden (RCB any degree), or complete pathological...
Abstract Introduction The selection of a method for measuring the insertion length nasogastric tubes in newborns is an important factor establishing safe use this device. Objective objective was to verify whether there difference proportion correctly placed when using nose, earlobe, mid‐umbilicus (NEMU) and weight‐based equation length. Methods This study randomized, controlled, blinded comparing 2 methods at neonatal unit, with intensive intermediate care, on 162 randomized individuals....
Abstract A complete deficiency of anterior pituitary hormones from several etiologies characterizes Panhypopituitarism (PH). Despite advances in treatment, patients with PH maintain high rates morbidity and mortality, a reason to investigate some insulin sensitivity, metabolic inflammatory parameters that could be related the increase these indicators. This was cross-sectional study comprising 41 under hormonal replacement, except for growth hormone, 37 individuals control group (CG) similar...
Surgical manipulations of the axilla may cause a condition known as Axillary Web Syndrome (AWS). The systems compromised and sequence events leading to this syndrome remains unknown. This study evaluated clinical, surgical, vascular factors associated with onset duration AWS after breast cancer surgery.In prospective study, 155 women were included. They submitted physical examination that consisted ultrasound Doppler axillary brachial vessels evaluation in 1, 3, 6 months surgery. Women...
Background: The use of gastric tubes in newborns admitted to a neonatal intensive care unit is fairly high, and there risk serious complications related this procedure. Purpose: Considering the need find method that does not involve patient's exposure radiation, study aimed evaluate diagnostic accuracy ultrasonography for verifying tube placement newborns. Methods: This was prospective, double-blind, observational performed unit, which 159 infants had intubation using ultrasound examination...
Abstract Aim To investigate whether pelvic floor muscle (PFM) morphological changes obtained through four‐dimensional translabial ultrasound (4D TLUS) correlate with a PFM contraction as evaluated by digital palpation and electromyographic activity surface electromyography (sEMG). The secondary objective was to which parameter is more strongly associated palpation. Methods This cross‐sectional study included 210 women their PFMs were (graded according the Modified Oxford Scale), sEMG 4D...
To compare body composition between women with premature ovarian insufficiency (POI) using hormone therapy and controls normal function, to correlate cardiovascular risk markers in the POI group.A case-control study of 70 matched by age mass index controls.All were submitted whole-body dual-energy X-ray absorptiometry (DXA) analyse composition. In group, total cholesterol, HDL-cholesterol, LDL-cholesterol, VLDL-cholesterol, triglycerides, glucose, insulin, transaminases C-reactive protein...
Objective To provide a straightforward approach to the sequential use of ultrasound (US), magnetic resonance (MR) and serum biomarkers in order differentiate origin pelvic masses, making most efficient these diagnostic resources. Study design This is cross-sectional study with 159 patients (133 ovarian 26 non-ovarian tumors) who underwent surgery/biopsy for an adnexal mass. Preoperative CA125 CEA measurements were obtained pelvic/abdominal was performed. MR studies performed all patients....
Background Vaginal laxity is an underreported condition that negatively affects women’s sexual function and their relationships. Evidence-based studies are needed to better understand this complaint discuss its treatment options. Thus, we present a study protocol compare the effect of radiofrequency pelvic floor muscle training in women with complaints vaginal laxity. Methods/Design This prospective, parallel-group, two-arm, randomized clinical trial (Registry: RBR-2zdvfp–REBEC)....
OBJECTIVE: To evaluate mammographic breast density in asymptomatic menopausal women correlation with clinical and sonographic findings. MATERIALS AND METHODS: Mammograms findings of 238 patients were retrospectively reviewed the period from February/2022 to June/2006. The following variables analyzed: patterns, findings, patients' age, parity, body mass index use hormone replacement therapy. RESULTS: Age, parity showed a negative pattern, while therapy positive correlation. Supplementary...
Objectives To prospectively investigate the diagnostic accuracy and clinical consequences of power Doppler morphologic criteria shear wave elastography (SWE) as complementary imaging methods for evaluation suspected local breast cancer recurrence in ipsilateral or chest wall. Methods Thirty‐two masses with a suspicion on B‐mode ultrasonography underwent SWE evaluations. Power were classified avascular, hypovascular, hypervascular. Shear was according to 5‐point scale (SWE score) maximum...