A5043522669- Pesticide Residue Analysis and Safety
- Metabolomics and Mass Spectrometry Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Analytical Chemistry and Chromatography
- Pesticide and Herbicide Environmental Studies
- Analytical chemistry methods development
- Mass Spectrometry Techniques and Applications
- Insect and Pesticide Research
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced Chemical Sensor Technologies
- DNA and Nucleic Acid Chemistry
- Advanced Nanomaterials in Catalysis
- Insect Pest Control Strategies
- Environmental Toxicology and Ecotoxicology
- Advanced biosensing and bioanalysis techniques
- Isotope Analysis in Ecology
- RNA and protein synthesis mechanisms
- Edible Oils Quality and Analysis
- Molecular Sensors and Ion Detection
- Allelopathy and phytotoxic interactions
- Antibiotics Pharmacokinetics and Efficacy
- Amino Acid Enzymes and Metabolism
- Chemical Synthesis and Analysis
- Molecular spectroscopy and chirality
- NMR spectroscopy and applications
Centre de Formation et de Recherche sur les Environnements Méditerranéens
2024
Université de Perpignan
2016-2024
Centre de Recherches Insulaires et Observatoire de l'Environnement
2016-2022
École Pratique des Hautes Études
2016-2021
Université Paris Sciences et Lettres
2017-2021
Centre National de la Recherche Scientifique
2012-2021
University of Padua
2014-2018
Centre National pour la Recherche Scientifique et Technique (CNRST)
2016
Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement
2011-2015
Université Claude Bernard Lyon 1
2012-2015
Monolayer-protected nanoparticles provide a straightforward access to self-organized receptors that selectively bind different substrates in water. Molecules featuring kinds of noncovalent interactions (namely, hydrophobic, ion pairing, and metal-ligand coordination) can be grafted on the nanoparticle surface tailored binding sites for virtually any class substrate. Not only selectivity but also strength these modulated. Such recognition ability exploited with new sensing protocols, based...
Properly designed monolayer-protected nanoparticles (2 nm core diameter) can be used as nanoreceptors for selective detection and identification of phenethylamine derivatives (designer drugs) in water. The molecular recognition mechanism is driven by the combination electrostatic hydrophobic interactions within coating monolayer. Each nanoparticle bind up to 30-40 analyte molecules. affinity constants range from 105 106 M-1 are modulated hydrophobicity aromatic moiety substrate. Detection...
By exploiting a magnetization transfer between monolayer-protected nanoparticles and interacting analytes, the NMR chemosensing protocol provides general approach to convert supramolecular receptors into chemosensors via their conjugation with nanoparticles. In this context, provide receptor not only "bulkiness" necessary for but also different selectivity as compared parent receptor. We here demonstrate that gold of 1.8 nm core coated monolayer 18-crown-6 ether derivatives can detect...
This work describes the development of a sensitive analytical method to determine simultaneously traces tetracycline and fluoroquinolone antibiotics in sludge soil, based on PLE extraction, followed by SPE purification finally an analysis LC-MS/MS. Recoveries were greater than 87% case fluoroquinolones between 25.4 41.7% for tetracyclines. Low relative standard deviations (<15%) obtained both matrices. The limits quantification comprised 1.1 4.6 ng/g 5 20 soil sludge, respectively. was...
Abstract A simple and effective method for high‐sensitivity NMR detection of selected compounds is reported. The combines 1D diffusion filter experiments small monolayer‐protected nanoparticles as high‐affinity receptors. Once bound to the nanoparticles, coefficient analyte decreases in such way that spectral editing based on filters can separate its signals from those other mixture components. Using functionalized with Zn 2+ ‐triazacyclonane complexes, identification phosphorylated organic...
Solution-phase self-association characteristics and DNA molecular-recognition properties are reported for three close analogues of minor-groove-binding ligands from the thiazotropsin class lexitropsin molecules; they incorporate isopropyl thiazole as a lipophilic building block. Thiazotropsin B (AcImPy(iPr) ThDp) shows similar self-assembly to A (FoPyPy(iPr) ThDp), although it is engineered, by incorporation imidazole in place N-methyl pyrrole, swap its recognition target 5'-ACTAGT-3'...
In this work, we develop a self-consistent route to inspect the conformational mobility of single chains in gold nanoparticles passivated with monolayer decanethiols. The approach is based on match between theoretical modeling under coarse-grained level (i.e., system definition, buildup free energy profiles along relevant coordinates, modeling/parametrization friction, production stochastic trajectories) and experimental spectroscopic investigations. agreement calculated values 13C NMR...
Rationale Correct biomarker determination in metabolomics is crucial for unbiased conclusions and reliable applications. However, this subject to several drifts, e.g. matrix effects ion suppression Liquid Chromatography/Mass Spectrometry (LC/MS)‐based approaches. This phenomenon provokes critical issues determination, particularly during comparative studies dealing with samples exhibiting heterogeneous complexities. Methods Occurrence of the issue was coincidentally noticed when studying...
Metabolomics is a powerful approach that allows for high throughput analysis and the acquisition of large biochemical data. Nonetheless, it still faces several challenging requirements, such as development optimal extraction analytical methods able to respond its qualitative quantitative requisites. Hence, objective present article suggest LC–HRMS-based untargeted profiling aiming provide performant tools help assess performance quality methods. It applied in herbicide-contaminated soil...
The increasing use of chemicals requires a better understanding their presence and dynamics in the environment as well impact on ecosystems; it is therefore important to set up procedures. aim this study was validate first steps an innovative multi-omics approach based metabolomics 16S metabarcoding data for future analyses contaminants fate Mediterranean lagoons. First, semi targeted analytical procedures water sediment matrices were evaluate lagoon contamination status. Forty-six compounds...
Abstract Commercial solutions of pesticides consist two main components: The active substance and the formulation ingredients. These ingredients, mainly composed polymeric surfactants, are considered inert vis‐à‐vis targeted organisms nature. Nonetheless, a relatively low attention is given to their analysis fate tracking in environment. In this context, current paper, embedded large study impact formulated soil, focuses on these It highlights discusses characteristic response ingredients...
Evidence of chemical plant protection products' (PPPs) long-term impact has been found in all environmental compartments. Therefore, other types PPPs are developed to complement like from natural sources, namely biocontrol products (BPs). Little is known about those new BPs, and it important assess their potential impact. Recently, the Environmental Metabolic Footprinting (EMF) approach was developed. It permits studying sample's entire meta-metabolome (endometabolome xenometabolome) through...