A5074470294- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Catalytic Cross-Coupling Reactions
- Synthetic Organic Chemistry Methods
- Shoulder and Clavicle Injuries
- Sarcoma Diagnosis and Treatment
- Management of metastatic bone disease
- Carbon dioxide utilization in catalysis
- Bone Tumor Diagnosis and Treatments
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Shoulder Injury and Treatment
- Orthopedic Surgery and Rehabilitation
- Reconstructive Surgery and Microvascular Techniques
- Cardiac Imaging and Diagnostics
- Total Knee Arthroplasty Outcomes
- Periodontal Regeneration and Treatments
- Central Venous Catheters and Hemodialysis
- Venous Thromboembolism Diagnosis and Management
- LGBTQ Health, Identity, and Policy
- Catalytic C–H Functionalization Methods
- Coronary Interventions and Diagnostics
- Trauma Management and Diagnosis
- Synthesis and Biological Evaluation
- Ferrocene Chemistry and Applications
- Simulation-Based Education in Healthcare
Rutgers, The State University of New Jersey
2018-2024
Rutgers New Jersey Medical School
2018-2024
American Society for Surgery of the Hand
2020
NYU Langone Health
2017-2018
New York University
2017-2018
Biostats (United States)
2018
Columbia University Irving Medical Center
2017
University of St Andrews
2006-2011
Guy's and St Thomas' NHS Foundation Trust
2010
Rhabdomyosarcoma is the most common soft-tissue sarcoma in children and adolescents accounts for 3% of all pediatric tumors. Subtypes include alveolar, spindle cell, embryonal, mixed-type, pleomorphic, rhabdomyosarcoma with ganglionic differentiation. The National Cancer Institute's Surveillance, Epidemiology, End Results (SEER) database was queried patients diagnosed any type between 1973 2014. Patient demographics, tumor characteristics, incidence were studied χ2 analysis. Survival modeled...
Masculinizing top surgery (bilateral mastectomy with chest wall reconstruction) is an important gender-affirming procedure sought by many transmasculine and nonbinary individuals. Current literature focused primarily on details of surgical technique complication rates, limited data available how affects subjective quality-of-life measures.An anonymous online survey was distributed to 81 the senior author's former top-surgery patients. The response rate 72 percent (58 respondents). Responses...
An N-heterocyclic carbene promotes the rearrangement of α-amino acid derived O-acyl carbonates to their corresponding C-acylated isomers, generating a C−C bond and quaternary stereocenter with high efficiency, under mild reaction conditions low catalyst loadings.
Wide variations in fat graft survival have been reported. The authors hypothesize that treating the adipose tissue on Telfa gauze creates a processed lipoaspirate with more functional adipokine profile improves survival.Suction-assisted was harvested from humans and either by centrifugation, rolled gauze, or left unprocessed. Progenitor cell populations were quantified characterized flow cytometry. Glycerol-3-phosphate dehydrogenase assay used to measure adipocytes. lipoaspirates grafted...
Screening of a range azolium salts, bases and solvents for reactivity indicates that triazolinylidenes, generated in situ with KHMDS THF, promote the Steglich rearrangement oxazolyl carbonates high catalytic efficiency (typical reaction time 5 min at <1.5 mol % NHC). This protocol shows wide substrate applicability, even allowing efficient generation vicinal quaternary centers. An improved experimental procedure is also described allows simplified one-pot to be employed similarly efficiency.
Despite increasing popularity of platelet-rich plasma (PRP) in treating aging facial skin, the quality evidence supporting its use is poor due to lack consistent methods preparation and application.This study was conducted assess treatment efficacy patient satisfaction with a single PRP prepared simplified application technique.Four millilitre were injected into 6 standardized points on each side face. Outcomes assessed by independent physician evaluation pretreatment posttreatment...
Cascade reaction sequences incorporating N-heterocyclic carbene-based organocatalysis have been developed that allow the direct preparation of a range (+/-)-4-phenoxycarbonylazlactones in good isolated yields (66-84%) from corresponding N-p-anisoyl amino acids.
The structural requirements of amidines necessary to act as efficient O- C-carboxyl transfer agents are delineated and the scope this process outlined through its application a range oxazolyl, benzofuranyl indolyl carbonates.
The O- to C-carboxyl transfer of oxazolyl carbonates promoted by triazolinylidenes, generated in situ with NEt3, shows a markedly different rate and chemoselectivity profile the same reaction triazolinylidenes using KHMDS. mechanism these pathways has been probed through extensive crossover studies understand this process. use NEt3 as base allows domino multi-step sequences be developed, although chiral NHCs only generate modest levels asymmetric induction (<15% ee) processes.
Abstract Backgrounds and Objectives Following tumor resection involving the acetabulum (periacetabular), various methods of reconstruction exist. The objective this study was to analyze functional outcomes complication rates by extent periacetabular resection, as well method reconstruction. Methods Twenty‐three patients underwent for a primary pelvic bone from 1993‐2018 at single institution. Complications were documented assessed using Musculoskeletal Tumor Society (MSTS) scoring system....
Retinoblastoma is considered the most common intraocular malignancy in childhood, comprising 4% of all pediatric cancers. Management retinoblastoma has evolved over past two decades and intra-ophthalmic artery chemotherapy emerged as a new modality globe-conserving treatment with excellent results. This achieves effective tumor reduction by delivering localized chemotherapy, decreases enucleation rate, minimizes systemic local side effects.We report case an 8-year-old girl late presentation...
The ability of N-heterocyclic carbenes to promote O-to-C carboxyl transfer on a range indolyl and benzofuranyl carbonates is examined, the scope limitations this process delineated.
Snow blowers represent a highly preventable and increasingly common mechanism of hand injury. This study examines current safety features their impact on decreasing the incidence snow blower-related injuries.The National Electronic Injury Surveillance System was queried to look for injuries related use throwers or between 2001 2016. From all blowers, we collected information identifying characteristics, location injury, type injury (i.e., avulsion). Chi-squared tests were used categorical...