- Endometrial and Cervical Cancer Treatments
- Endometriosis Research and Treatment
- Cancer survivorship and care
- Hernia repair and management
- Cervical Cancer and HPV Research
- Ovarian cancer diagnosis and treatment
- Lymphatic System and Diseases
- Colorectal Cancer Surgical Treatments
- Polyomavirus and related diseases
- Urological Disorders and Treatments
- Sexual function and dysfunction studies
- Urinary and Genital Oncology Studies
- Family Support in Illness
- Advances in Oncology and Radiotherapy
- Anorectal Disease Treatments and Outcomes
- Clinical practice guidelines implementation
- Pelvic floor disorders treatments
Amsterdam UMC Location University of Amsterdam
2011-2018
Centrum voor Gynaecologische Oncologie Amsterdam
2016
To compare long-term morbidity and quality of life after primary surgery or radiotherapy for stage IB/II cervical cancer.A cross-sectional study was performed. Patients treated cancer between 2000 2010 were approached to participate. Primary treatment consisted radical hysterectomy with pelvic lymphadenectomy (RHL), selected cases followed by adjuvant (chemo-)radiotherapy, (chemo)radiotherapy (PRT). European Organization Research Treatment Cancer-C30 Cancer-CX24 questionnaires administered....
To assess whether sexual distress among cervical cancer (CC) survivors is associated with frequently reported vaginal symptoms, other proposed biopsychosocial factors and worries about painful intercourse mediate the relation between symptoms distress.A cross-sectional study was conducted 194 sexually active partnered CC aged 25 to 69 years. Sexual distress, pain worry, anxiety, depression, body image concerns, relationship dissatisfaction sociodemographic variables age, time since...
<h3>Objective</h3> This study aimed to describe the pattern of recurrence and survival related prognostic variables, including type surgery as a clinical variable, in patients surgically treated for early cervix cancer. <h3>Methods</h3> Records 2124 who underwent radical hysterectomy International Federation Gynaecology Obstetrics stage I/IIA cervical cancer between 1982 2011 were reviewed. Clinical-pathologic also extent parametrectomy, identified used multivariable Cox proportional hazard...
Objective This study aimed to compare urinary and bowel symptoms quality of life (QoL) among women treated with a Wertheim–Meigs (WM, type III) or Wertheim–Okabayashi (WO, IV) radical hysterectomy pelvic lymphadenectomy for early-stage cervical cancer. Methods In this cross-sectional observational study, patients WO (nerve sparing) WM (with without adjuvant radiotherapy) between January 2000 December 2010 in the Center Gynaecological Oncology Amsterdam Leiden University Medical were...
<h3>Objective</h3> Radical hysterectomy with pelvic lymphadenectomy (RHL) is the preferred treatment for early-stage cervical cancer. Although oncological outcome good regard to recurrence and survival rates, it well known that RHL might result in postoperative bladder impairments due autonomic nerve disruption. The network has been extensively studied, but anatomy of fibers branching off inferior hypogastric plexus innervate less known. Besides, pathogenesis dysfunction after multifactorial...
Management regarding completing hysterectomy in case of intraoperative finding positive lymph nodes early-stage cervical cancer differs between institutions. The aim this study was to compare survival and toxicity after completed followed by adjuvant (chemo-)radiotherapy versus abandoned primary treatment with chemoradiotherapy (CRT).A retrospective multicenter cohort performed. All patients were scheduled for radical pelvic lymphadenectomy (RHL). In the RHL group, (chemo-)radiotherapy....
Abstract Introduction There is ongoing discussion about the primary treatment of women with bulky early‐stage cervical cancer. Because high number patients who need adjuvant (chemo)radiotherapy after initial surgical treatment, some state that should be choice to prevent morbidity. The aim our study assess results radical surgery for cancer in terms recurrence patterns and survival. Materials methods We conducted a retrospective cohort study. included 129 underwent hysterectomy pelvic...
We highly appreciate the comments by Drs.Wang, Horng and Lee regarding our feasibility study on prevention of radiation cystitis intravesical instillations with chondroitin sulphate [1].We fully agree that more pre-clinical studies may help to elucidate mechanisms treatment cystitis, several clinical are needed assess efficacy sulphate.In fact, we hope soon start a double-blind in patients undergoing primary or adjuvant radiotherapy for gynaecological malignancies.In trial, wider range early...