A5075327249- Diagnosis and Treatment of Venous Diseases
- Thermoregulation and physiological responses
- Venous Thromboembolism Diagnosis and Management
- Nutritional Studies and Diet
- Systemic Sclerosis and Related Diseases
- Heart Rate Variability and Autonomic Control
- Peripheral Artery Disease Management
- Obesity, Physical Activity, Diet
- Cardiovascular and exercise physiology
- Diet and metabolism studies
- Physical Activity and Health
- Cardiovascular Health and Disease Prevention
- Diabetic Foot Ulcer Assessment and Management
- Ovarian function and disorders
- Infrared Thermography in Medicine
- Consumer Attitudes and Food Labeling
- Smoking Behavior and Cessation
- Pressure Ulcer Prevention and Management
- Lymphatic System and Diseases
- Climate Change and Health Impacts
- Stroke Rehabilitation and Recovery
- Eating Disorders and Behaviors
- Sports injuries and prevention
- Reproductive Biology and Fertility
- Exercise and Physiological Responses
Sheffield Hallam University
2016-2025
Heart Research UK
2021
King's College London
2021
SK Group (Japan)
2018
Center for Health, Exercise and Sport Sciences
2017-2018
University of Nottingham
2003-2016
University of Hertfordshire
2009-2013
University of Lincoln
2012
Northern General Hospital
2008-2010
University of Derby
2005
The aging effect on microvascular integrity, marked by endothelial dysfunction and reduction in exercise tolerance, is a major cause of CVD (cardiovascular disease). Improved dietary habits, known to reduce morbidity mortality, are also attenuate those effects. present study investigated the effects combined MD (Mediterranean diet) intervention lower- upper-limb cutaneous functions an older healthy population. A total 22 sedentary participants (age, 55±4 years) underwent cardiopulmonary...
This study compared the effects of a 2-week program low-volume high-intensity interval training (HIT) with higher-volume moderate-intensity continuous (CT) on cardiopulmonary and vascular functions in postmenopausal women.Twenty-two women were randomly assigned to undertake six HIT (n = 12) or CT 10) sessions for 2 weeks. consisted ten 1-minute intervals cycling exercise at 100% peak power output separated by 1 minute active recovery. involved 40 minutes 65% output. Variables assessed...
Venous leg ulcers (VLUs) are typically painful and heal slowly. Compression therapy offers high healing rates; however, improvements not usually sustained. Exercise is a low-cost, low-risk effective strategy for improving physical mental health. Little known about the feasibility efficacy of supervised exercise training used in combination with compression patients VLUs.To assess 12-week programme as an adjunct to VLUs.This was two-centre, two-arm, parallel-group, randomized trial....
Smoking is a major risk factor for cardiovascular disease and smoking cessation reduces excess risk. E-cigarettes are popular but there little evidence on their health effect. Our objective was to compare the medium- longer-term effects in smokers attempting quit using e-cigarettes with or without nicotine prescription replacement therapy (NRT).
This study tested the potential risk-reduction benefits of Mediterranean Diet (MD) and regular exercise training on microvascular activity cardiorespiratory capacity in postmenopausal women. Fifteen sedentary participants (age = 54.6 ± 3.6) were randomised into either or combined with following MD for eight-weeks, assessed their capacity, upper- lower-limb endothelial cutaneous vascular conductance (CVC) test using Laser Doppler Fluximetry (LDF), coupled measuring endothelium-dependent...
Sleep is a vital element of adolescents’ overall health; it influences their body and mind thus affects quality life. Adequate sleep duration are essential for maintaining optimal metabolic health lowering the risk developing several medical conditions, such as cardiovascular disease. The current study aimed to assess perceived 1717 European adolescents from three different countries (Spain, Iceland Estonia) aged 13- 16-years (900 boys, 817 girls) using Pittsburgh Quality Index (PSQI). A...
The ability to increase skin blood flow (SkBF) rapidly in response local heating is diminished with advanced age; however, the mechanisms are unclear. primary aim of this study was investigate role sensory nerves age-related change. A secondary effect aerobic fitness on nerve-mediated vasodilatation young and aged skin. We measured SkBF (using laser Doppler flowmetry) older endurance-trained untrained men (n = 7 each group) at baseline during 35 min 42°C two sites ventral forearm. One site...
Sedentary aging results in a diminished rapid cutaneous vasodilator response to local heating. We investigated whether this was due altered contributions of noradrenergic sympathetic nerves by assessing 1) the age-related decline and 2) effect aerobic fitness. Using laser-Doppler flowmetry, we measured skin blood flow (SkBF) young (24 ± 1 yr) older (64 endurance-trained sedentary men (n = 7 per group) at baseline during 35 min heating 42°C untreated forearm sites, sites treated with...
Aerobic exercise in general and high-intensity interval training (HIIT) specifically is known to improve vascular function a range of clinical conditions. HIIT particular has demonstrated improvements outcomes, conditions that have strong macroangiopathic component. Nevertheless, the effect on microcirculation systemic sclerosis (SSc) patients yet be investigated. Therefore, purpose study was compare effects two protocols (cycle arm cranking) digital area SSc patients. Thirty-four limited...
Sarcopenia is characterized by a loss of muscle mass and function, with significant implications for the physical performance affected people. Although commonly associated aging, disease-related sarcopenia great clinical importance, particularly as it impacts disease progression outcomes. Individuals rheumatic diseases (RDs), including rheumatoid arthritis, systemic sclerosis, spondyloarthritides, lupus erythematosus, fibromyalgia, myositis, or vasculitis, exhibit high prevalence sarcopenia,...
To investigate the effects of a 12-week supervised exercise programme on lower-limb cutaneous microvascular reactivity in adults with venous leg ulceration. Thirty-eight unilateral ulceration who were being treated compression therapy (58% male; mean age 65 years; median ulcer size 5 cm2) randomly allocated to or control groups. Exercise participants (n = 18) invited attend thrice weekly sessions aerobic and resistance for 12 weeks. Cutaneous was assessed gaiter region ulcerated...
Abstract Background Polycystic ovary syndrome (PCOS) affects up to 20% of women and is characterised by higher amounts visceral fat, obesity, insulin resistance, dyslipidemia reproductive cardiometabolic complications. Increased oxidised low-density lipoprotein (LDL) concentrations have been associated with an increased risk cardiovascular disease (CVD)-related events. Oxidised LDL rarely used as a marker for CVD in PCOS-related studies despite its widely accepted role atherogenesis the...
Effective public health interventions rely on understanding how individuals access, interpret, and utilise information. Studying the information-seeking behaviour (HISB) of a community can provide valuable insights to inform strategies that address needs challenges. This study explored online HISBs People African Descent (PoAD) in United Kingdom (UK), demographic comprises four percent UK population has 92.8% active Internet usage rate. Data HISB were collected from 21 PoAD across various...
The study was carried out to investigate whether pretreatment haemoglobin (Hb) levels act as a biomarker in the management of patients with locally advanced rectal cancer.We prospectively collected data on all within our cancer network localized low treated preoperative radiotherapy/chemoradiotherapy at Mount Vernon Centre for Cancer Treatment between March 1994 and July 2008. Pretreatment Hb level assessed an independent variable whole sample dichotomised value 12 g/dl. A multivariate...
<i>Purpose of Study:</i> Non-invasive laser Doppler fluximetry (LDF) and imaging (LDI), combined with iontophoresis, have been used to study the microcirculation in a range clinical conditions including lower limb venous disease. A prerequisite for an accurate measurement tool is that it reproducible. However, there currently no literature respect reproducibility LDF LDI iontophoresis (in general) upright position specific). Furthermore, two techniques interchangeably by...
Venous leg ulcers are common, chronic wounds that painful and reduce quality of life. Compression therapy is known to assist in the healing venous ulceration. Supervised exercise training targets an improvement calf muscle pump function might be a useful adjunctive for enhancing ulcer other aspects physical mental health. However, evidence individuals with sparse. Here, we describe protocol study aims assess feasibility undertaking randomised controlled trial supervised programme people who...