A5071165773- Health and Lifestyle Studies
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Nutrition, Genetics, and Disease
- Physical Activity and Health
- Nutrition and Health in Aging
- Diet and metabolism studies
- Frailty in Older Adults
- Aging, Health, and Disability
- Cardiovascular and exercise physiology
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Consumer Attitudes and Food Labeling
- Health disparities and outcomes
- Genetic Associations and Epidemiology
- Cardiovascular Health and Risk Factors
- Health Systems, Economic Evaluations, Quality of Life
- Cancer Risks and Factors
- Economic and Financial Impacts of Cancer
- Body Composition Measurement Techniques
- Cardiac Health and Mental Health
- COVID-19 Clinical Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Liver Disease Diagnosis and Treatment
- Mobile Health and mHealth Applications
- Dementia and Cognitive Impairment Research
University of Glasgow
2016-2025
Catholic University of the Maule
2020-2025
Arturo Prat University
2024-2025
Instituto Maimónides de Investigación Biomédica de Córdoba
2024
Biomedical Research Institute
2024
University of Córdoba
2024
Universidad Católica de la Santísima Concepción
2024
Universidad de La Frontera
2024
British Heart Foundation
2019-2023
Universidad Mayor
2017-2023
Abstract Objective To investigate the association of grip strength with disease specific incidence and mortality whether enhances prediction ability an established office based risk score. Design Prospective population study. Setting UK Biobank. Participants 502 293 participants (54% women) aged 40-69 years. Main outcome measures All cause as well from cardiovascular disease, respiratory chronic obstructive pulmonary cancer (all cancer, colorectal, lung, breast, prostate). Results Of...
Objectives To investigate severe COVID-19 risk by occupational group. Methods Baseline UK Biobank data (2006–10) for England were linked to SARS-CoV-2 test results from Public Health (16 March 26 July 2020). Included participants employed or self-employed at baseline, alive and aged <65 years in 2020. Poisson regression models adjusted sequentially baseline demographic, socioeconomic, work-related, health, lifestyle-related factors assess ratios (RRs) testing positive hospital death due...
<b>Objective</b> To investigate the association between active commuting and incident cardiovascular disease (CVD), cancer, all cause mortality. <b>Design</b> Prospective population based study. <b>Setting</b> UK Biobank. <b>Participants</b> 263 450 participants (106 674 (52%) women; mean age 52.6), recruited from 22 sites across UK. The exposure variable was mode of transport used (walking, cycling, mixed <i>v</i> non-active (car or public transport)) to commute work on...
Purpose Imprecise measurement of physical activity variables might attenuate estimates the beneficial effects on health-related outcomes. We aimed to compare cardiometabolic risk factor dose-response relationships for and sedentary behaviour between accelerometer- questionnaire-based measures. Methods Physical were assessed in 317 adults by 7-day accelerometry International Activity Questionnaire (IPAQ). Fasting blood was taken determine insulin, glucose, triglyceride total, LDL HDL...
Understanding of the role ethnicity and socioeconomic position in risk developing SARS-CoV-2 infection is limited. We investigated this UK Biobank study.
Background: Optimal nutritional choices are linked with better health, but many current interventions to improve diet have limited effect. We tested the hypothesis that providing personalized nutrition (PN) advice based on information individual and lifestyle, phenotype and/or genotype would promote larger, more appropriate, sustained changes in dietary behaviour. Methods: Adults from seven European countries were recruited an internet-delivered intervention (Food4Me) randomized to: (i)...
Combinations of lifestyle factors interact to increase mortality. traditional such as smoking and alcohol are well described, but the additional effects emerging television viewing time not. The effect socioeconomic deprivation on these extended risks also remains unclear. We aimed examine whether modifies association between an score lifestyle-related risk health outcomes.Data for this prospective analysis were sourced from UK Biobank, a population-based cohort study. assigned all...
Introduction Older people have been reported to be at higher risk of COVID-19 mortality. This study explored the factors mediating this association and whether older age was associated with increased mortality in absence other factors. Methods In UK Biobank, a population cohort study, baseline data were linked deaths. Poisson regression used between current Results Among eligible participants, 438 (0.09%) died COVID-19. Current exponentially Overall, participants aged ≥75 years 13-fold (95%...
To estimate the risk of acute myocardial infarction (AMI) or stroke in adults with non-alcoholic fatty liver disease (NAFLD) steatohepatitis (NASH).Matched cohort study.Population based, electronic primary healthcare databases before 31 December 2015 from four European countries: Italy (n=1 542 672), Netherlands (n=2 225 925), Spain (n=5 488 397), and UK (n=12 695 046).120 795 a recorded diagnosis NAFLD NASH no other diseases, matched at time (index date) by age, sex, practice site, visit,...
Higher body mass index (BMI) is a risk factor for cardiometabolic disease; however, the underlying causal associations remain unclear.To use UK Biobank data to report estimates of association between BMI and disease outcomes traits, such as pulse rate, using mendelian randomization.Cross-sectional baseline from population-based cohort study including 119 859 participants with complete phenotypic (medical sociodemographic) genetic data. Participants attended 1 22 assessment centers across...
To quantify the association of self-reported walking pace and handgrip strength with all-cause, cardiovascular, cancer mortality. A total 230 670 women 190 057 men free from prevalent cardiovascular disease were included UK Biobank. Usual was self-defined as slow, steady/average or brisk. Handgrip assessed by dynamometer. Cox-proportional hazard models adjusted for social deprivation, ethnicity, employment, medications, alcohol use, diet, physical activity, television viewing time....
It is unclear whether the potential benefits of physical activity differ according to level cardiorespiratory fitness (CRF) or strength. The aim this study was determine association between and mortality moderated by CRF grip strength sufficiently inform health promotion strategies. 498 135 participants (54.7% women) from UK Biobank were included (CRF data available in 67 702 participants). Exposure variables strength, CRF, activity. All-cause cardiovascular disease (CVD) events outcomes....
The data regarding the associations of body mass index (BMI) with cardiovascular (CVD) risk, especially for those at low categories BMI, are conflicting. aim our study was to examine composition (assessed by five different measures) incident CVD outcomes in healthy individuals.A total 296 535 participants (57.8% women) white European descent without baseline from UK biobank were included. Exposures measures adiposity. Fatal and non-fatal events primary outcome. Low BMI (≤18.5 kg m-2)...
Total cholesterol and high-density lipoprotein (HDL-C) measurements are central to cardiovascular disease (CVD) risk assessment, but there is continuing debate around the utility of other lipids for prediction.
We aimed to investigate demographic, lifestyle, socioeconomic and clinical risk factors for COVID-19, compared them pneumonia influenza in UK Biobank.
People with obesity and a normal metabolic profile are sometimes referred to as having 'metabolically healthy obesity' (MHO). However, whether this group of individuals actually 'healthy' is uncertain. This study aims examine the associations MHO wide range obesity-related outcomes.This population-based prospective cohort 381,363 UK Biobank participants median follow-up 11.2 years. was defined BMI ≥ 30 kg/m2 at least four six metabolically criteria. Outcomes included incident diabetes fatal...
Abstract Background Although non-alcoholic fatty liver disease (NAFLD) is linked to inflammation, whether an inflammatory diet increases the risk of NAFLD unclear. This study aimed examine association between Energy-adjusted Diet Inflammatory Index (E-DII) score and severe using UK Biobank. Methods prospective cohort included 171,544 Biobank participants. The E-DII was computed 18 food parameters. Associations incident (defined as hospital admission or death) were first investigated by...