Andrew Schlafly

ORCID: 0000-0002-8866-8210
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About
Contact & Profiles
Research Areas
  • Healthcare cost, quality, practices
  • Adipokines, Inflammation, and Metabolic Diseases
  • Health and Medical Research Impacts
  • Legal Education and Practice Innovations
  • Inflammasome and immune disorders
  • Cancer Genomics and Diagnostics
  • Diversity and Career in Medicine
  • Diabetes and associated disorders
  • Evolution and Genetic Dynamics
  • Genetic Associations and Epidemiology

University of Pennsylvania
2019-2022

National Cancer Institute
2019

Division of Cancer Epidemiology and Genetics
2019

Joslin Diabetes Center
2019

New York Proton Center
2006

Objectives Differences in National Institutes of Health (NIH) funding between specialties may affect research and patient outcomes that are less well funded.The aim this study is to evaluate how NIH has been awarded by medical specialty. This assesses differences trends the amount funding, specialty, for years 2011–2020, via a retrospective analysis data from RePORTER (Research Portfolio Online Reporting Tools Expenditures Results). Study design Longitudinal cross-sectional Setting 2011 2020...

10.1136/bmjopen-2021-058191 article EN cc-by-nc BMJ Open 2022-12-01

Despite genetics being accepted as the primary cause of familial aggregation for most diseases, it is still unclear whether afflicted families are likely to share a single highly penetrant rare variant, many minimally common variants, or combination two types variants. We therefore use recent estimates SNP heritability and liability threshold model estimate proportion carry rare, causal variant. then show that Polygenic Risk Scores (PRS) may be useful identifying such variant prioritizing...

10.1371/journal.pgen.1008490 article EN public-domain PLoS Genetics 2019-11-15
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