- Heart Rate Variability and Autonomic Control
- Spaceflight effects on biology
- Cardiovascular Syncope and Autonomic Disorders
- Non-Invasive Vital Sign Monitoring
- Cardiovascular and exercise physiology
- Blood Pressure and Hypertension Studies
- High Altitude and Hypoxia
- Healthcare Systems and Practices
- Cardiovascular Function and Risk Factors
- Space Exploration and Technology
- Thermoregulation and physiological responses
- Cardiac Arrest and Resuscitation
- Stroke Rehabilitation and Recovery
- Meat and Animal Product Quality
- Heart rate and cardiovascular health
- Complex Systems and Time Series Analysis
- Sleep and Work-Related Fatigue
- Chaos control and synchronization
- Pulmonary Hypertension Research and Treatments
- Cardiac Imaging and Diagnostics
- ECG Monitoring and Analysis
- Health and Wellbeing Research
- Botulinum Toxin and Related Neurological Disorders
- Circadian rhythm and melatonin
- Atrial Fibrillation Management and Outcomes
KU Leuven
2005-2015
University of Padua
2012
Hospices Civils de Lyon
2012
Hôpital Louis Pradel
2012
Hospital Universitario Reina Sofía
2012
Jessa Hospital
2012
Akershus University Hospital
2012
Institute of Experimental Cardiology
2006-2009
Universitair Ziekenhuis Leuven
2003-2005
In recent years more studies are using nonlinear dynamics to describe cardiovascular control. Because of the large dispersion physiological data, it is important have with both male and female participants establish a range healthy values. This study investigated effect gender age on indexes. Nonlinear scaling properties were studied by 1/f slope (where f frequency), fractal dimension, detrended fluctuation analysis short- long-term correlations (DFAalpha(1) DFAalpha(2), respectively)....
Key points Syncope is a common clinical condition occurring even in healthy people without manifest cardiovascular disease; we determined the role of cardiac output and sympathetic vasoconstriction neurally mediated (pre)syncope. Our data showed that moderate fall with coincident vasodilatation occurred majority (64%) presyncopal subjects, while marked output, driven predominantly by decrease heart rate, no changes total peripheral resistance at presyncope, smaller (36%) subset. Sympathetic...
1. The present study assesses the effects of autonomic blockade (alpha- and beta-adrenoceptor cholinergic) on cardiovascular function studied by heart rate variability (HRV), blood pressure (BPV) baroreflex sensitivity in rats using non-linear dynamics. Little is known about influence pharmacological nervous system interventions regulatory indices. 2. In 13 conscious rats, aortic were measured continuously before, during after with atropine, phentolamine propranolol. Non-linear scaling...
After heart transplantation, the donor is extrinsically denervated. No input of sympathetic or vagal nerves can influence rate, resulting in a flat power spectrum beat-to-beat variability. The occurrence and significance reinnervation remain controversial.We monitored evolution rate variability (HRV) after starting from few weeks postoperatively up to 10 years surgery. Twenty-four-hour Holter recordings 216 heart-transplant patients were analyzed using time frequency domain analysis HRV....
NTG (nitroglycerine) is used in routine tilt testing to elicit a vasovagal response. In the present study we hypothesized that with increasing age triggers more gradual BP (blood pressure) decline due diminished baroreflex-buffering capacity. The purpose of was examine effect on baroreflex control patients distinct age-related collapse patterns. groups consisted 29 (16–71 years old, 17 females) clinically suspected VVS (vasovagal syncope) and positive test. Mean FAP (finger arterial...
This study examined the effects of hypnosis on autonomic cardiac control. We hypothesized a modification modulation heart rate with an enhanced vagal tone during compared to baseline.In 12 healthy subjects (6 men and 6 women, 22.2 +/- 1.0 years age) ECG was recorded at baseline hypnosis. Heart variability parameters were obtained in frequency domain (LFnu: low normalized units, HFnu: high units) from nonlinear analysis methods (detrended fluctuation analysis, DFA).Compared control condition,...
The purpose of this study was to evaluate the effects a realistic, feasible, and commonly used fitness training programme on cardiac autonomic control in 14 sedentary men aged 62.0 +/- 6.1 years (mean s). All participants performed one-year which intensity frequency were specifically chosen be compliant for majority (2-3 sessions per week at moderate intensity). At same time, reference group consisting 15 age-matched (age 64.2 6.5 years) did not change their habitual physical activity....
Abstract Aim: Astronauts commonly return from space with altered short‐term cardiovascular dynamics and blunted baroreflex sensitivity. Although many studies have addressed this issue, post‐flight effects on the dynamic circulatory control remain incompletely understood. It is not clear how long system needs to recover spaceflight as most investigations only extended between a few days 2 weeks. Methods: In study, we examined effect of short‐duration (1–2 weeks) respiratory‐mediated rhythms...
We reported previously that two otherwise identical training programs at lower (LI) and higher intensity (HI) similarly reduced resting systolic blood pressure (BP) by approximately 4-6 mmHg. Here, we determined the effects of both on BP-regulating mechanisms, biomarkers systemic inflammation prothrombotic state heart. In this cross-over study (3 × 10 weeks), healthy participants exercised three times 1 h/week at, respectively, 33% 66% heart rate (HR) reserve, in a random order, with...
Our immediate goal was to study heart rate variability (HRV) in chicken embryos the egg. Instantaneous data were needed for this purpose, and accordingly an ECG recording method egg developed. The aim of work test hypothesis that autonomic nervous cardiac modulation, as shown from HRV parameters, is present at end development it reaches a constant value during last days incubation. Embryonic obtained final incubation period (days 19 20) recordings. Tachograms computed time- frequency-domain...
Sustained weightlessness affects all body functions, among these also cardiac autonomic control mechanisms. How this may influence neural response to central stimulation by a mental arithmetic task remains an open question. The hypothesis was tested that microgravity alters cardiovascular standardized cognitive load stimuli. Beat-to-beat heart rate, brachial blood pressure, and respiratory frequency were collected in five astronauts, taking part three different short-duration (10 11 days)...
Non-linear analysis of heart rate variability (HRV) can give additional information about autonomic control the rate. This study applied fractal dimension (FD) in a congestive failure (CHF) population.FD and HRV were evaluated healthy population (n=21) an end-stage using 1-h segments during day night from Holter recordings.CHF patients presented loss circadian variation both FD conventional time- frequency-domain indices. was higher CHF night. In correlation between high-frequency power...
Spaceflight and head-down bed rest (HDBR) can induce the orthostatic intolerance (OI); mechanisms remain to be clarified. The aim of this study was determine whether or not OI after HDBR relates degree autonomic cardiovascular adaptation. Fourteen volunteers were enrolled for 60 days HDBR. A head-up tilt test (HUTT) performed before Our data revealed that, in all nonfainters, there a progressive increase heart rate over course HDBR, which remained higher until 12 recovery. mean arterial...
Purpose The objective was to investigate autonomic control in groups of European and Chinese astronauts identify similarities differences. Methods Beat-to-beat heart rate finger blood pressure, brachial respiratory frequency were measured from 10 (five taking part three different space missions five two missions). Data recording performed the supine standing positions at least days before launch, 1, 3, after return. Cross-correlation analysis systolic pressure used assess cardiac baroreflex...