Shanguang Chen

ORCID: 0000-0002-7030-8196
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Spaceflight effects on biology
  • Human-Automation Interaction and Safety
  • Space Exploration and Technology
  • EEG and Brain-Computer Interfaces
  • Circadian rhythm and melatonin
  • Non-Invasive Vital Sign Monitoring
  • Neural and Behavioral Psychology Studies
  • Sleep and Work-Related Fatigue
  • High Altitude and Hypoxia
  • Heart Rate Variability and Autonomic Control
  • Risk and Safety Analysis
  • Color perception and design
  • Ergonomics and Musculoskeletal Disorders
  • Spatial Cognition and Navigation
  • Traffic and Road Safety
  • Neuroscience and Neural Engineering
  • Occupational Health and Safety Research
  • Photoacoustic and Ultrasonic Imaging
  • Cancer-related molecular mechanisms research
  • Paranormal Experiences and Beliefs
  • Safety Warnings and Signage
  • Bioinformatics and Genomic Networks
  • Optical Imaging and Spectroscopy Techniques
  • Alzheimer's disease research and treatments
  • Robotics and Automated Systems

China Astronaut Research and Training Center
2016-2025

Tianjin University
2014-2024

Southeast University
2019-2024

Tsinghua University
2024

State Key Laboratory of Space Medicine Fundamentals and Application
2011-2022

Tianjin Medical University
2019-2022

Tianjin International Joint Academy of Biomedicine
2022

BioMimetic Systems (United States)
2022

Biosensores (Spain)
2022

Chinese Academy of Medical Sciences & Peking Union Medical College
2020

Neuroimaging-based functional connectivity (FC) analyses have revealed significant developmental trends in specific intrinsic networks linked to cognitive and behavioral maturation. However, knowledge of how brain maturation is associated with FC dynamics at rest limited. Here, we examined age-related differences the temporal variability data publicly released by Nathan Kline Institute (NKI) (n=183, ages 7-30) showed that dynamic inter-region interactions can be used accurately predict...

10.3389/fnhum.2015.00418 article EN cc-by Frontiers in Human Neuroscience 2015-07-16

This study provides a new application of convolutional neural networks for drowsiness detection based on electrooculography (EOG) signals. Drowsiness is charged to be one the major causes traffic accidents. Such helpful reduce losses casualty and property. Most attempts at EOG involve feature extraction step, which accounted as time-consuming task, it difficult extract effective features. In this paper, an unsupervised learning proposed estimate driver fatigue EOG. A network with linear...

10.1109/ijcnn.2014.6889642 article EN 2022 International Joint Conference on Neural Networks (IJCNN) 2014-07-01

Abstract The human visual perceptual system is highly sensitive to biological motion (BM) but less its inverted counterpart. This inversion effect may stem from our selective sensitivity gravity-constrained life signals and confer an adaptive advantage creatures living on Earth. However, what extent how such shaped by the Earth’s gravitational field heretofore unexplored. Taking of a spaceflight experiment ground-based analog via 6° head-down tilt bed rest (HDTBR), we show that prolonged...

10.1038/s41467-022-30347-y article EN cc-by Nature Communications 2022-05-19

Sustained cardiac pressure overload-induced hypertrophy and pathological remodeling frequently leads to heart failure. Casein kinase-2 interacting protein-1 (CKIP-1) has been identified be an important regulator of cell proliferation, differentiation, apoptosis. However, the physiological role CKIP-1 in is unknown.The results echocardiography histology demonstrate that CKIP-1-deficient mice exhibit spontaneous with aging hypersensitivity hypertrophy, as well. Transgenic cardiac-specific...

10.1161/circulationaha.112.102780 article EN Circulation 2012-11-15

Long-term spaceflight induces both physiological and psychological changes in astronauts. To understand the neural mechanisms underlying these changes, it is critical to investigate effects of microgravity on functional architecture brain. In this study, we used resting-state MRI (rs-fMRI) study whether brain altered after 45 days -6° head-down tilt (HDT) bed rest, which a reliable model for simulation microgravity. Sixteen healthy male volunteers underwent rs-fMRI scans before HDT rest....

10.3389/fnbeh.2014.00200 article EN cc-by Frontiers in Behavioral Neuroscience 2014-06-05

Sliding tactile perception is a basic function for human beings to determine the mechanical properties of object surfaces and recognize materials. Imitating this process, paper proposes novel finger-shaped sensor based on thin piezoelectric polyvinylidene fluoride (PVDF) film surface texture measurement. A parallelogram mechanism designed ensure that applies constant contact force perpendicular surface, 2-dimensional movable structure utilized generate relative motion at certain speed...

10.3390/s140304899 article EN cc-by Sensors 2014-03-11

This present study was designed to investigate the different effects of ginsenosides Rb1 and Rg1 on improving cognitive deficits in 4-month-old SAMP8 mice. Mice were divided into six groups, including group, + Donepezil (1.6 mg/kg) (30 60 µmol/kg), µmol/kg) groups. SAMR1 mice same age used as control group. Ginsenosides donepezil administrated orally animals for 8 weeks, then learning memory ability measured by using Morris water maze (MWM) test, object recognition test passive avoidance...

10.3389/fphar.2020.00834 article EN cc-by Frontiers in Pharmacology 2020-06-10

Prolonged bed rest may cause changes in the autonomic nervous system that are related to cognition and emotion. This study adopted an emotional flanker task evaluate effect of 45 days -6° head-down (HDBR) on executive functioning 16 healthy young men at each six time points: second-to-last day before period, eleventh, twentieth, thirty-second fortieth during eighth after period. In addition, self-report inventories (Beck Anxiety Inventory, BAI; Beck Depression BDI; Positive Affect Negative...

10.1371/journal.pone.0052160 article EN cc-by PLoS ONE 2012-12-17

For future interplanetary manned spaceflight, mental issues, as well physiological problems, must inevitably be considered and solved. Mars500 is a high-fidelity ground simulation experiment that involved 520 days of confined isolation for six multinational crewmembers. This provided good opportunity to perform psycho-physiological psycho-social researches on such missions. To investigate emotional responses psychological adaptation over long-term confinement, the International Affective...

10.1371/journal.pone.0087087 article EN cc-by PLoS ONE 2014-04-02

Attention is important in error processing. Few studies have examined the link between sustained attention and In this study, we how error-related negativity (ERN) of a four-choice reaction time task was reduced mental fatigue condition investigated role Forty-one recruited participants were divided into two groups. experiment group, 20 subjects performed an additional continuous psychomotor vigilance test (PVT) for 1 h. normal 21 only experimental procedures without PVT test. Fatigue states...

10.1371/journal.pone.0117837 article EN cc-by PLoS ONE 2015-03-10

20(S)-protopanaxatriol (PPT), one of the ginsenosides from Panax ginseng, has been reported to have neuroprotective effects and improve memory. The present study was designed investigate protective effect PPT on scopolamine-induced cognitive deficits in mice. Male Institute Cancer Research mice were pretreated with 2 different doses (20 40 μmol/kg) for 27 days by intraperitoneal injection, scopolamine (0.75 mg/kg) injected intraperitoneally 9 induce memory impairment. Thirty minutes after...

10.1002/ptr.6044 article EN Phytotherapy Research 2018-02-22

Objective Attention forms the foundation for formation of situation awareness. Low awareness can lead to driving performance decline, which be dangerous in driving. The goal this study is investigate how different types pre-takeover tasks, involving cognitive, visual and physical resources engagement, as well individual attentional function, affect driver's attention restoration conditionally automated

10.1080/15389588.2024.2427865 article EN Traffic Injury Prevention 2025-01-10

Sleep deprivation significantly impairs cognitive function, which disrupts daily life. However, sex differences in these impairments are not well understood, as most preclinical studies primarily use male animals, neglecting potential between sexes. This study aims to investigate sex-specific function under sleep using reward-based operant conditioning tasks. Sprague-Dawley rats were pre-trained on a lever-press task and subsequently divided into control chronic restriction (CSR) groups. The...

10.1186/s12993-025-00268-z article EN cc-by-nc-nd Behavioral and Brain Functions 2025-02-28
Coming Soon ...