- Spaceflight effects on biology
- Human-Automation Interaction and Safety
- Space Exploration and Technology
- EEG and Brain-Computer Interfaces
- Circadian rhythm and melatonin
- Non-Invasive Vital Sign Monitoring
- Neural and Behavioral Psychology Studies
- Sleep and Work-Related Fatigue
- High Altitude and Hypoxia
- Heart Rate Variability and Autonomic Control
- Risk and Safety Analysis
- Color perception and design
- Ergonomics and Musculoskeletal Disorders
- Spatial Cognition and Navigation
- Traffic and Road Safety
- Neuroscience and Neural Engineering
- Occupational Health and Safety Research
- Photoacoustic and Ultrasonic Imaging
- Cancer-related molecular mechanisms research
- Paranormal Experiences and Beliefs
- Safety Warnings and Signage
- Bioinformatics and Genomic Networks
- Optical Imaging and Spectroscopy Techniques
- Alzheimer's disease research and treatments
- Robotics and Automated Systems
China Astronaut Research and Training Center
2016-2025
Tianjin University
2014-2024
Southeast University
2019-2024
Tsinghua University
2024
State Key Laboratory of Space Medicine Fundamentals and Application
2011-2022
Tianjin Medical University
2019-2022
Tianjin International Joint Academy of Biomedicine
2022
BioMimetic Systems (United States)
2022
Biosensores (Spain)
2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2020
Neuroimaging-based functional connectivity (FC) analyses have revealed significant developmental trends in specific intrinsic networks linked to cognitive and behavioral maturation. However, knowledge of how brain maturation is associated with FC dynamics at rest limited. Here, we examined age-related differences the temporal variability data publicly released by Nathan Kline Institute (NKI) (n=183, ages 7-30) showed that dynamic inter-region interactions can be used accurately predict...
This study provides a new application of convolutional neural networks for drowsiness detection based on electrooculography (EOG) signals. Drowsiness is charged to be one the major causes traffic accidents. Such helpful reduce losses casualty and property. Most attempts at EOG involve feature extraction step, which accounted as time-consuming task, it difficult extract effective features. In this paper, an unsupervised learning proposed estimate driver fatigue EOG. A network with linear...
Abstract The human visual perceptual system is highly sensitive to biological motion (BM) but less its inverted counterpart. This inversion effect may stem from our selective sensitivity gravity-constrained life signals and confer an adaptive advantage creatures living on Earth. However, what extent how such shaped by the Earth’s gravitational field heretofore unexplored. Taking of a spaceflight experiment ground-based analog via 6° head-down tilt bed rest (HDTBR), we show that prolonged...
Sustained cardiac pressure overload-induced hypertrophy and pathological remodeling frequently leads to heart failure. Casein kinase-2 interacting protein-1 (CKIP-1) has been identified be an important regulator of cell proliferation, differentiation, apoptosis. However, the physiological role CKIP-1 in is unknown.The results echocardiography histology demonstrate that CKIP-1-deficient mice exhibit spontaneous with aging hypersensitivity hypertrophy, as well. Transgenic cardiac-specific...
Long-term spaceflight induces both physiological and psychological changes in astronauts. To understand the neural mechanisms underlying these changes, it is critical to investigate effects of microgravity on functional architecture brain. In this study, we used resting-state MRI (rs-fMRI) study whether brain altered after 45 days -6° head-down tilt (HDT) bed rest, which a reliable model for simulation microgravity. Sixteen healthy male volunteers underwent rs-fMRI scans before HDT rest....
Sliding tactile perception is a basic function for human beings to determine the mechanical properties of object surfaces and recognize materials. Imitating this process, paper proposes novel finger-shaped sensor based on thin piezoelectric polyvinylidene fluoride (PVDF) film surface texture measurement. A parallelogram mechanism designed ensure that applies constant contact force perpendicular surface, 2-dimensional movable structure utilized generate relative motion at certain speed...
This present study was designed to investigate the different effects of ginsenosides Rb1 and Rg1 on improving cognitive deficits in 4-month-old SAMP8 mice. Mice were divided into six groups, including group, + Donepezil (1.6 mg/kg) (30 60 µmol/kg), µmol/kg) groups. SAMR1 mice same age used as control group. Ginsenosides donepezil administrated orally animals for 8 weeks, then learning memory ability measured by using Morris water maze (MWM) test, object recognition test passive avoidance...
Prolonged bed rest may cause changes in the autonomic nervous system that are related to cognition and emotion. This study adopted an emotional flanker task evaluate effect of 45 days -6° head-down (HDBR) on executive functioning 16 healthy young men at each six time points: second-to-last day before period, eleventh, twentieth, thirty-second fortieth during eighth after period. In addition, self-report inventories (Beck Anxiety Inventory, BAI; Beck Depression BDI; Positive Affect Negative...
For future interplanetary manned spaceflight, mental issues, as well physiological problems, must inevitably be considered and solved. Mars500 is a high-fidelity ground simulation experiment that involved 520 days of confined isolation for six multinational crewmembers. This provided good opportunity to perform psycho-physiological psycho-social researches on such missions. To investigate emotional responses psychological adaptation over long-term confinement, the International Affective...
Attention is important in error processing. Few studies have examined the link between sustained attention and In this study, we how error-related negativity (ERN) of a four-choice reaction time task was reduced mental fatigue condition investigated role Forty-one recruited participants were divided into two groups. experiment group, 20 subjects performed an additional continuous psychomotor vigilance test (PVT) for 1 h. normal 21 only experimental procedures without PVT test. Fatigue states...
20(S)-protopanaxatriol (PPT), one of the ginsenosides from Panax ginseng, has been reported to have neuroprotective effects and improve memory. The present study was designed investigate protective effect PPT on scopolamine-induced cognitive deficits in mice. Male Institute Cancer Research mice were pretreated with 2 different doses (20 40 μmol/kg) for 27 days by intraperitoneal injection, scopolamine (0.75 mg/kg) injected intraperitoneally 9 induce memory impairment. Thirty minutes after...
Objective Attention forms the foundation for formation of situation awareness. Low awareness can lead to driving performance decline, which be dangerous in driving. The goal this study is investigate how different types pre-takeover tasks, involving cognitive, visual and physical resources engagement, as well individual attentional function, affect driver's attention restoration conditionally automated
Sleep deprivation significantly impairs cognitive function, which disrupts daily life. However, sex differences in these impairments are not well understood, as most preclinical studies primarily use male animals, neglecting potential between sexes. This study aims to investigate sex-specific function under sleep using reward-based operant conditioning tasks. Sprague-Dawley rats were pre-trained on a lever-press task and subsequently divided into control chronic restriction (CSR) groups. The...