A5088553436- Neuroscience and Neural Engineering
- Muscle activation and electromyography studies
- EEG and Brain-Computer Interfaces
- Conducting polymers and applications
- Advanced Memory and Neural Computing
- Transcranial Magnetic Stimulation Studies
- Pain Management and Treatment
- 3D Printing in Biomedical Research
- Bone Tissue Engineering Materials
- Tactile and Sensory Interactions
University of Cambridge
2021-2024
The spinal cord is crucial for transmitting motor and sensory information between the brain peripheral systems. Spinal injuries can lead to severe consequences, including paralysis autonomic dysfunction. We introduce thin-film, flexible electronics circumferential interfacing with cord. This method enables simultaneous recording stimulation of dorsal, lateral, ventral tracts a single device. Our findings include successful signal capture elicitation in anesthetized rats, proof-of-concept...
Spinal cord stimulation is one of the oldest and most established neuromodulation therapies. However, today, clinicians need to choose between bulky paddle-type devices, requiring invasive surgery under general anesthetic, percutaneous lead-type which can be implanted via simple needle puncture local anesthetic but offer clinical drawbacks when compared with paddle devices. By applying photo- soft lithography fabrication, we have developed a device that features thin, flexible electronics...
Abstract Neural recording systems have significantly progressed to provide an advanced understanding and treatment for neurological diseases. Flexible transistor‐based active neural probes exhibit great potential in electrophysiology applications due their intrinsic amplification capability tissue‐compliant nature. However, most current bulky back‐end connectivity since the output is current, development of integrated circuit voltage crucial near‐sensor signal processing at abiotic/biotic...
Abstract Electrocorticography is an established neural interfacing technique wherein array of electrodes enables large-area recording from the cortical surface. commonly used for seizure mapping however implantation electrocorticography arrays a highly invasive procedure, requiring craniotomy larger than implant area to place device. In this work, flexible thin-film electrode are combined with concepts soft robotics, realize device that can change shape via integrated fluidic actuators. We...
Implantable electronic medical devices are used in functional mapping of the brain before surgery and to deliver neuromodulation for treatment neurological neuropsychiatric disorders. Their electrode arrays assembled by hand, this leads bulky form factors with limited flexibility low counts. Thin film implants, made using microfabrication techniques, emerging as an attractive alternative, they offer dramatically improved conformability enable high density recording stimulation. A major...
Abstract The spinal cord, as an extension of the central nervous system, is one most important entities in body, notably carrying motor information from brain to peripheral systems and sensory periphery into brain. Injuries cord can lead catastrophic effects, including paralysis, pain autonomic dysfunction. In this work, we explored use thin-film, flexible electronics circumferentially interface with leading a new paradigm recording stimulating dorsal, lateral, ventral tracts simultaneously...